Katsuyuki Kaneda, Yuchio Yanagawa and Tadashi Isa Transient enhancement of inhibition following visual cortical lesions in the mouse superior colliculus European Journal of Neuroscience 36
We investigated the changes in local circuit dynamics of the sSC after receiving visual cortical lesions in mice. In vivo unit recordings revealed that about 1 week after the lesions, surround suppression was transiently enhanced. Whole-cell recordings in slice preparations showed that the lesion induced cell type-dependent changes in the excitation-inhibition balance. The results suggest that enhanced synaptic inhibition may be responsible for the enhanced surround suppression in the sSC.
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