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Zoltán Somogyvári, Dorottya Cserpán, István Ulbert and Péter Érdi Localization of single-cell current sources based on extracellular potential patterns: the spike CSD method European Journal of Neuroscience 36

Version of Record online: 31 AUG 2012 | DOI: 10.1111/j.1460-9568.2012.08249.x

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A new, spike CSD (sCSD) method has been developed to reveal CSD distribution of single cells during action potential generation, based on the inverse solution of the Poisson-equation. Simulations showed, that the sCSD method reconstructed the original CSD more precisely than the traditional CSD. Applying our method to spikes, measured in cat A1 cortex with a 16 channel linear probe in vivo, the cell-electrode distances were estimated and the spatio-temporal CSD distributions were reconstructed.

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