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Daisuke Takahara, Ken-ichi Inoue, Yoshihiro Hirata, Shigehiro Miyachi, Atsushi Nambu, Masahiko Takada and Eiji Hoshi Multisynaptic projections from the ventrolateral prefrontal cortex to the dorsal premotor cortex in macaques – anatomical substrate for conditional visuomotor behavior European Journal of Neuroscience 36

Article first published online: 13 AUG 2012 | DOI: 10.1111/j.1460-9568.2012.08251.x

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Both the ventrolateral prefrontal cortex (vlPFC) and the dorsal premotor cortex (PMd) are implicated in conditional visuomotor behavior, in which it is required to determine an action based on an associated visual object. However, virtually no direct projections appear to exist between vlPFC and PMd. Here we provide evidence that vlPFC outflow is directed toward PMd in a multisynaptic fashion through the dorsal prefrontal cortex (dPFC) and the dorsomedial motor cortex (dmMC).

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