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M. J. Lelos, D. J. Harrison and S. B. Dunnett Intrastriatal excitotoxic lesion or dopamine depletion of the neostriatum differentially impairs response execution in extrapersonal space European Journal of Neuroscience 36

Version of Record online: 26 AUG 2012 | DOI: 10.1111/j.1460-9568.2012.08256.x

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In order to elucidate more fully the function of the neostriatum, the experiment examined the differential impact of unilateral dopamine depletion or excitoxic lesion on response execution in ipsilateral and contralateral space at up to four levels of eccentricity. Distinct differences in the profiles of impairment were evident after each type of neural dysfunction, which has important implications for understanding the role of the striatum in egocentrically defined response localisation.

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