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Takayuki Suzuki, Honami Sakata, Chiaki Kato, John A. Connor and Mitsuhiro Morita Astrocyte activation and wound healing in intact-skull mouse after focal brain injury European Journal of Neuroscience 36

Version of Record online: 27 SEP 2012 | DOI: 10.1111/j.1460-9568.2012.08280.x

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A novel rodent closed-head injury model using intense light exposure through thinned-skull cranial window manifested reproducible cortical tissue recovery. The recovery process was characterised by two distinct reactive astrocyte populations. Nestin-expressing and proliferating astrocytes extended processes radially over perilesional recoverying region, whereas distal region was populated by non-proliferating hypertrophic astrocytes.

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