Takayuki Suzuki, Honami Sakata, Chiaki Kato, John A. Connor and Mitsuhiro Morita Astrocyte activation and wound healing in intact-skull mouse after focal brain injury European Journal of Neuroscience 36
A novel rodent closed-head injury model using intense light exposure through thinned-skull cranial window manifested reproducible cortical tissue recovery. The recovery process was characterised by two distinct reactive astrocyte populations. Nestin-expressing and proliferating astrocytes extended processes radially over perilesional recoverying region, whereas distal region was populated by non-proliferating hypertrophic astrocytes.
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