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Antonio J. López-Farré, José J. Zamorano-León, Antonio Segura, Petra J. Mateos-Cáceres, Javier Modrego, Pablo Rodríguez-Sierra, Laura Calatrava, Juan Tamargo and Carlos Macaya Plasma desmoplakin I biomarker of vascular recurrence after ischemic stroke Journal of Neurochemistry 121

Version of Record online: 13 MAR 2012 | DOI: 10.1111/j.1471-4159.2012.07683.x

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Plasma desmoplakin I and vascular post-stroke recurrence The present study used proteomics to identify novel plasma biomarkers associated with vascular recurrence in post-stroke ischemic patients. High plasma desmoplakin I levels in patients taking statins in the three first months after the first ischemic stroke were associated with protection against a new vascular event in one year of follow-up. This result suggests that plasma desmoplakin I may serve as a biomarker for good response to statins in post-stroke ischemic patients.

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