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W. Gao, Y. Lu, B. El Essawy, M. Oukka, V. K. Kuchroo and T. B. Strom Contrasting Effects of Cyclosporine and Rapamycin in De Novo Generation of Alloantigen-Specific Regulatory T Cells American Journal of Transplantation 7

Article first published online: 19 MAY 2007 | DOI: 10.1111/j.1600-6143.2007.01842.x

In this mouse model, using reporter mice for Foxp3, sirolimus promotes de novo conversion of alloantigen specific Treg cells, whereas cyclosporine inhibits this process.

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