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M. D. Stegall, T. Diwan, S. Raghavaiah, L. D. Cornell, J. Burns, P. G. Dean, F. G. Cosio, M. J. Gandhi, W. Kremers and J. M. Gloor Terminal Complement Inhibition Decreases Antibody-Mediated Rejection in Sensitized Renal Transplant Recipients American Journal of Transplantation 11

Version of Record online: 22 SEP 2011 | DOI: 10.1111/j.1600-6143.2011.03757.x

This study demonstrates that the blockade of terminal complement activation with the C5-specific antibody eculizumab decreases the incidence of early antibody-mediated rejection in living donor renal transplant recipients who have high levels of donor specific alloantibody. See editorial by Woodle and Baldwin on page 2277.

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