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P. A. Jacobson, D. Schladt, W. S. Oetting, R. Leduc, W. Guan, A. J. Matas and A. Israni Lower Calcineurin Inhibitor Doses in Older Compared to Younger Kidney Transplant Recipients Yield Similar Troughs American Journal of Transplantation 12

Article first published online: 4 SEP 2012 | DOI: 10.1111/j.1600-6143.2012.04232.x

This study demonstrates that elderly kidney transplant recipients receive significantly lower doses of calcineurin inhibitors than younger recipients but yet maintain higher trough concentrations, suggesting age-related changes in metabolism.

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