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D. P. Al-Adra, R. Pawlick, A. M. J. Shapiro and C. C. Anderson Targeting Cells Causing Split Tolerance Allows Fully Allogeneic Islet Survival With Minimal Conditioning in NOD Mixed Chimeras American Journal of Transplantation 12

Version of Record online: 13 SEP 2012 | DOI: 10.1111/j.1600-6143.2012.04260.x

The authors show, in the NOD model of type-1 diabetes that is highly resistant to mixed chimerism approaches to prevent islet rejection, that a nonmyeloablative protocol based on depleting cells allows longterm mixed chimerism and fully allogeneic donor islet survival.

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