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T. Isakova, H. Xie, S. Messinger, F. Cortazar, J. J. Scialla, G. Guerra, G. Contreras, D. Roth, G. W. Burke III, M. Z. Molnar, I. Mucsi and M. Wolf Inhibitors of mTOR and Risks of Allograft Failure and Mortality in Kidney Transplantation American Journal of Transplantation 13

Article first published online: 1 OCT 2012 | DOI: 10.1111/j.1600-6143.2012.04281.x

The authors conduct an observational study of 139,370 recipients who underwent kidney transplantation between 1999 and 2010 in the United States and find that compared with calcineurin-inhibitor-based regimens, use of mammalian target of rapamycin–based regimens for primary immunosuppression is associated with inferior recipient survivals.

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