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A. Ceschi, C. Rauber-Lüthy, H. Kupferschmidt, N. R. Banner, M. Ansari, S. Krähenbühl and A. B. Taegtmeyer Acute Calcineurin Inhibitor Overdose: Analysis of Cases Reported to a National Poison Center Between 1995 and 2011 American Journal of Transplantation 13

Version of Record online: 27 DEC 2012 | DOI: 10.1111/j.1600-6143.2012.04347.x

This study investigates 28 cases of overdose with the calcineurin inhibitors cyclosporine and tacrolimus, and shows that acute enteral overdoses are generally well tolerated and respond to enteral decontamination measures that reduce drug absorption, but that acute intravenous overdoses are less well tolerated.

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