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Lincoln R. Potter Natriuretic peptide metabolism, clearance and degradation The FEBS Journal 278

Version of Record online: 7 APR 2011 | DOI: 10.1111/j.1742-4658.2011.08082.x

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Natriuretic peptides are a family of three related pleiotropic signaling factors that bind and activate transmembrane guanylyl cyclases. This review initially discusses the general characteristics of natriuretic peptides and their receptors. The tissue specific metabolism of natriuretic peptides and their degradation by individual proteases and natriuretic peptide receptor C-mediated internalization are then more specifically discussed.

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