Subramanyam Swaminathan Molecular structures and functional relationships in clostridial neurotoxins FEBS Journal 278
Article first published online: 13 JUN 2011 | DOI: 10.1111/j.1742-4658.2011.08183.x
Clostridium botulinum neurotoxins are the most potent toxins known. They cause botulism, a deadly disease in humans and animals, and are both public health hazard and potential biowarfare agent. Botulinum neurotoxin consists of multiple domains, each domain being responsible for a specific function in its toxicity. This review describes their molecular structures and discusses the structure-function relation of each domain
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