E-mail a Wiley Online Library Link

Timo Eichner and Sheena E. Radford Understanding the complex mechanisms of β2-microglobulin amyloid assembly The FEBS Journal 278

Version of Record online: 13 JUN 2011 | DOI: 10.1111/j.1742-4658.2011.08186.x

Thumbnail image of graphical abstract

This review focuses on recent advances in developing a molecular description of the folding and aggregation mechanisms of the human amyloidogenic protein β2-microglobulin (β2m) under physiologically-relevant conditions. In particular, the structural and dynamic properties of the non-native folding intermediate IT and its role in the initiation of fibrillation and the development of dialysis-related amyloidosis are discussed

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field