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Petra Van Damme, Thomas Arnesen and Kris Gevaert Protein alpha-N-acetylation studied by N-terminomics FEBS Journal 278

Article first published online: 2 AUG 2011 | DOI: 10.1111/j.1742-4658.2011.08230.x

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N-terminomics is a powerful tool for studying protein N-terminal modifications including protein N-terminal acetylation, an ubiquitous modification catalyzed by multi-subunit N-terminal acetyltransferase complexes. In this review, we highlight the recent advances made in this expanding field and provide an overview of the observed functional implications of alpha-N-acetylation and present state-of-the-art technologies, all permitting for a better understanding of N-terminal biology

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