E-mail

E-mail a Wiley Online Library Link

Tomoyuki Ohba, Yujiro Ariga, Takashi Maruyama, Nha K. Truong, Jun-ichiro Inoue and Tatsushi Muta Identification of interleukin-1 receptor-associated kinase 1 as a critical component that induces post-transcriptional activation of IκB-ζ FEBS Journal 279

Article first published online: 30 NOV 2011 | DOI: 10.1111/j.1742-4658.2011.08416.x

Thumbnail image of graphical abstract

IκB-ζ, an essential inflammatory regulator, is specifically induced by Toll-like receptor ligands or interleukin-1β by post-transcriptional activation via a 165-nucleotide element in IκB-ζ mRNA. Here, we found that while either IRAK1/4 or TRAF6 induces NF-κB activation, activation of IRAK1/4, but not that of TRAF6, are sufficient to elicit the post-transcriptional activation of IκB-ζ, suggesting a new pathway activated by IRAK1.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

Choose captcha format: Image or Audio. Click here if you need help.

SEARCH