Wolfgang Peti, Angus C. Nairn and Rebecca Page Structural basis for protein phosphatase 1 regulation and specificity FEBS Journal 280
Article first published online: 24 FEB 2012 | DOI: 10.1111/j.1742-4658.2012.08509.x
Protein Phosphatase 1 (PP1) regulates diverse, essential cellular processes such as cell cycle progression, protein synthesis, muscle contraction, carbohydrate metabolism, transcription and neuronal signaling. We review recent advances in structural studies of PP1 holoenzyme complexes and summarize the new insights these studies have provided into the molecular basis of PP1 regulation and specificity.
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