E-mail a Wiley Online Library Link

Robert Karisch and Benjamin G. Neel Methods to monitor classical protein-tyrosine phosphatase oxidation The FEBS Journal 280

Version of Record online: 30 MAY 2012 | DOI: 10.1111/j.1742-4658.2012.08626.x

Thumbnail image of graphical abstract

Reversible oxidation, which inactivates PTPs, is emerging as an important cellular regulatory mechanism and contributes to human diseases, including cancer. Identifying ROS-inactivated PTPs could be tantamount to finding the PTP(s) that critically regulate a specific signaling pathway. This article provides an overview of the methods currently available to identify and quantify PTP oxidation and outlines future challenges in redox signaling.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field