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Kuldip Upadhyay, Atul Manvar, Kena Rawal, Sudhir Joshi, Jalpa Trivedi, Ravi Chaniyara and Anamik Shah Evaluation of Structurally Diverse Benzoazepines Clubbed with Coumarins as Mycobacterium tuberculosis Agents Chemical Biology & Drug Design 80

Version of Record online: 12 OCT 2012 | DOI: 10.1111/j.1747-0285.2012.01436.x

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In the present work, various coumarins clubbed with benzo(thi)diazepines were evaluated for their M. tuberculosis activity against H37Rv strains using MABA assay. The IC50 values of two analogs (compounds 5k and 5o) in level-2 screening were observed as >10 μg/mL and 3.63 μg/mL respectively.

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