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Zeynep Ates-Alagoz, Natalia Coleman, Marlena Martin, Aaron Wan and Adeboye Adejare Syntheses and In Vitro Anticancer Properties of Novel Radiosensitizers Chemical Biology & Drug Design 80

Version of Record online: 25 OCT 2012 | DOI: 10.1111/j.1747-0285.2012.01442.x

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Our most active compound 3d is significantly more effective than doxorubicin or lead compound 5c at the dose level of 10 μm, without and with radiation; and in MCF-7 and DU-145 cell lines. These results are very encouraging. Future studies include testing the compounds in vivo without and with radiation.

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