Koro Gotoh, Takayuki Masaki, Seiichi Chiba, Hisae Ando, Takanobu Shimasaki, Kimihiko Mitsutomi, Kansuke Fujiwara, Isao Katsuragi, Tetsuya Kakuma, Toshiie Sakata and Hironobu Yoshimatsu Nesfatin-1, corticotropin-releasing hormone, thyrotropin-releasing hormone, and neuronal histamine interact in the hypothalamus to regulate feeding behavior Journal of Neurochemistry 124
Nesfatin-1, corticotropin-releasing hormone (CRH), thyrotropin-releasing hormone (TRH) and hypothalamic neuronal histamine act as anorexigenics in the hypothalamus. Nesfatin-1 increased CRH and TRH levels and histamine turnover, whereas histamine also increased nesfatin-1 level in the hypothalamus. These results indicate that CRH, TRH and hypothalamic neuronal histamine mediate the suppressive effects of nesfatin-1 on feeding behavior.
Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf