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Frauke Steindel, Raissa Lerner, Martin Häring, Sabine Ruehle, Giovanni Marsicano, Beat Lutz and Krisztina Monory Neuron-type specific cannabinoid-mediated G protein signalling in mouse hippocampus Journal of Neurochemistry 124

Article first published online: 13 FEB 2013 | DOI: 10.1111/jnc.12137

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Neuron-type specific cannabinoid-mediated G protein signalling in mouse hippocampus

In this article we describe cell-type specific cannabinoid G protein signalling in the mouse hippocampus. Though most of hippocampal CB1 receptors can be found in the GABAergic neurons, they host only one third of the cannabinoid-activated G proteins. Glutamatergic neurons that express only the minority of CB1 accommodate two thirds of cannabinoid-activated G proteins.

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