E-mail a Wiley Online Library Link

Maryam S. Vasefi, Jeff S. Kruk, John J. Heikkila and Michael A. Beazely 5-Hydroxytryptamine type 7 receptor neuroprotection against NMDA-induced excitotoxicity is PDGFβ receptor dependent Journal of Neurochemistry 125

Version of Record online: 13 FEB 2013 | DOI: 10.1111/jnc.12157

Thumbnail image of graphical abstract

Growth factor receptors in the CNS are protective against several neuronal insults. However, it is difficult to introduce growth factors into the brain because of their large size. We identify a pathway whereby serotonin (5-HT) 7 receptor agonists (small organic molecules) increase the expression of the platelet-derived growth factor (PDGF) receptor to protect neurons against toxicity.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field