David Rotllant, Jordi Pastor-Ciurana and Antonio Armario Stress-induced brain histone H3 phosphorylation: contribution of the intensity of stressors and length of exposure Journal of Neurochemistry 125
Detailed knowledge about how the brain distinctly processes different types of emotional stressors is scarce. We demonstrate that phosphorylation of histone H3 (pH3) appears to be a good marker of stress-induced neuronal activation and show a more restricted pattern than classical marker such as c-fos. Detection of pH3 may help to more specifically identify brain areas and neurons important for the processing of emotional stressors.
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