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David Rotllant, Jordi Pastor-Ciurana and Antonio Armario Stress-induced brain histone H3 phosphorylation: contribution of the intensity of stressors and length of exposure Journal of Neurochemistry 125

Article first published online: 11 MAR 2013 | DOI: 10.1111/jnc.12214

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Detailed knowledge about how the brain distinctly processes different types of emotional stressors is scarce. We demonstrate that phosphorylation of histone H3 (pH3) appears to be a good marker of stress-induced neuronal activation and show a more restricted pattern than classical marker such as c-fos. Detection of pH3 may help to more specifically identify brain areas and neurons important for the processing of emotional stressors.

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