E-mail

E-mail a Wiley Online Library Link

Michael E. Cahill, Christine Remmers, Kelly A. Jones, Zhong Xie, Robert A. Sweet and Peter Penzes Neuregulin1 signaling promotes dendritic spine growth through kalirin Journal of Neurochemistry 126

Version of Record online: 27 JUN 2013 | DOI: 10.1111/jnc.12330

Thumbnail image of graphical abstract

NRG1 and erbB4 increase spine size, while NRG1 activity, but not erbB4 activity, increases spine density. NRG1 also increases spine GluA1 content, and the GEF kalirin is necessary for the ability of NRG1 and erbB4 to regulate spine morphogenesis. We find that environmental enrichment, which is known to stimulate spine morphogenesis in the forebrain, increases cortical and hippocampal erbB4 expression.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

SEARCH