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Sreejata Chatterjee and Sujit K. Sikdar Corticosterone targets distinct steps of synaptic transmission via concentration specific activation of mineralocorticoid and glucocorticoid receptors Journal of Neurochemistry 128

Article first published online: 28 OCT 2013 | DOI: 10.1111/jnc.12478

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The stress hormone corticosterone has multiple effects on neuronal physiology and function. In this study we show corticosterone differentially targets the steps of synaptic transmission depending on the genomic effects of its cognate receptors namely mineralocorticoid and glucocorticoid receptors (MR and GR), within its physiological range. Increasing concentrations of corticosterone enhanced synaptic transmission at distinct levels.

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