E-mail

E-mail a Wiley Online Library Link

Anantha Vijay R. Santhanam, Livius V. d'Uscio and Zvonimir S. Katusic Erythropoietin increases bioavailability of tetrahydrobiopterin and protects cerebral microvasculature against oxidative stress induced by eNOS uncoupling Journal of Neurochemistry 131

Article first published online: 6 AUG 2014 | DOI: 10.1111/jnc.12824

Thumbnail image of graphical abstract

We demonstrate that treatment with erythropoietin (EPO) could protect cerebral microvasculature against the pathological consequences of endothelial nitric oxide (NO) synthase uncoupling. Our results suggest that EPO might protect the neurovascular unit against oxidative stress by restoring bioavailability of tetrahydrobiopterin (BH4) and endothelial nitric oxide.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

Choose captcha format: Image or Audio. Click here if you need help.

SEARCH