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M. Geiger, Y. Guitton, M. Vansteelandt, I. Kerzaon, E. Blanchet, T. Robiou du Pont, J.C. Frisvad, P. Hess, Y.F. Pouchus and O. Grovel Cytotoxicity and mycotoxin production of shellfish-derived Penicillium spp., a risk for shellfish consumers Letters in Applied Microbiology 57

Version of Record online: 6 SEP 2013 | DOI: 10.1111/lam.12143

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Significance and Impact of the Study: Penicillium strains isolated from bivalve molluscs produce extracts exhibiting a higher cytotoxicity than extracts from Penicillium strains isolated from the surrounding marine environment. The use of a mussel-based medium for cultures of some shellfish-derived strains enhances the cytotoxicity of extracts when compared with classical media. The production of cytotoxic compounds and of the mycotoxin patulin on such a host-derived medium highlights a potential health risk for shellfish consumers.

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