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J. Matricon, E. Muller, A. Accarie, M. Meleine, M. Etienne, N. Voilley, J. Busserolles, A. Eschalier, M. Lazdunski, S. Bourdu, A. Gelot and D. Ardid Peripheral contribution of NGF and ASIC1a to colonic hypersensitivity in a rat model of irritable bowel syndrome Neurogastroenterology & Motility 25

Version of Record online: 31 JUL 2013 | DOI: 10.1111/nmo.12199

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Using a rat model of irritable bowel syndrome, the work presented herein shows that NGF-dependent ASIC1a channels peripheral overexpression in colonic DRG neurons is associated with colonic hypersensitivity.

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