E-mail

E-mail a Wiley Online Library Link

Kun Li, Mei Wang, Ting Wang, Dongmei Sun, Rongrong Zhu, Xiaoyu Sun, Xianzheng Wu and Shi-Long Wang Interaction of Retinoic Acid Radical Cation with Lysozyme and Antioxidants: Laser Flash Photolysis Study in Microemulsion Photochemistry and Photobiology 89

Article first published online: 17 AUG 2013 | DOI: 10.1111/php.12128

Thumbnail image of graphical abstract

355 nm laser flash photolysis of all-trans retinoic acid (ATRA) in microemulsion leads to the formation of retinoic acid cation radicals (ATRA•+) via biphotonic processes. Deprotonated form of ATRA is more favorable for the formation of ATRA•+. ATRA•+ is proved to be reactive to lysozyme, tyrosine and tryptophan which is suggestive of its destructive effect on proteins. Meanwhile, some antioxidants, such as curcumin, gallic acid and vitamin C, can efficiently interact with ATRA•+, which indicates that it may competitively protect proteins from the attack of ATRA•+ by inactivating free radical.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

SEARCH