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Julie A. Yager Erythema multiforme, Stevens–Johnson syndrome and toxic epidermal necrolysis: a comparative review Veterinary Dermatology 25

Article first published online: 3 JUL 2014 | DOI: 10.1111/vde.12142

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Background – Human erythema multiforme (EM) and Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) are separate conditions. There is no consensus on classification criteria for the eponymous diseases in animals. Conclusions and clinical importance – Histopathological lesions do not reliably differentiate EM, SJS and TEN. A multicentre study to develop a consensus set of clinical criteria for EM and SJS/TEN in animals is overdue. No adjunctive therapies, including intravenous immunoglobulin, have met evidence-based standards, but ciclosporin is promising.

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