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Daniel S Shin, Ayana Jordan, Samik Basu, Rajan M Thomas, Sanmay Bandyopadhyay, Edwin F de Zoeten, Andrew D Wells and Fernando Macian Regulatory T cells suppress CD4+ T cells through NFAT-dependent transcriptional mechanisms EMBO reports 15

Version of Record online: 29 JUL 2014 | DOI: 10.15252/embr.201338233

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Regulatory T cells are shown to induce the activation of NFAT1-dependent gene expression in stimulated T-helper cells, including the transcription of Ikaros, which is required for optimal T-helper cell suppression in vitro and in vivo.

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