Pulmonary rehabilitation for chronic obstructive pulmonary disease

  1. Figure 1

    Figure 1
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    Figure 1

    Study flow diagram.

  2. Figure 2

    Figure 2
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    Figure 2

    Risk of bias summary: review authors' judgements about each risk of bias item for each included study.

  3. Figure 3

    Figure 3
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    Figure 3

    Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.

  4. Figure 4

    Figure 4
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    Figure 4

    Funnel plot of comparison: 1 Rehabilitation versus usual care, outcome: 1.4 QoL - Change in CRQ (Dyspnoea) (see Table 1 for Egger and Begg-Mazumdar: Kendall's test results).

  5. Figure 5

    Figure 5
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    Figure 5

    Funnel plot of comparison: 1 Rehabilitation versus usual care, outcome: 1.5 QoL - Change in SGRQ (Total) (see Table 1 for Egger and Begg-Mazumdar: Kendall's test results).

  6. Analysis 1.1

    Analysis 1.1
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    Analysis 1.1

    Comparison 1 Rehabilitation versus usual care, Outcome 1 QoL - Change in CRQ (Fatigue).

  7. Analysis 1.2

    Analysis 1.2
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    Analysis 1.2

    Comparison 1 Rehabilitation versus usual care, Outcome 2 QoL - Change in CRQ (Emotional Function).

  8. Analysis 1.3

    Analysis 1.3
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    Analysis 1.3

    Comparison 1 Rehabilitation versus usual care, Outcome 3 QoL - Change in CRQ (Mastery).

  9. Analysis 1.4

    Analysis 1.4
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    Analysis 1.4

    Comparison 1 Rehabilitation versus usual care, Outcome 4 QoL - Change in CRQ (Dyspnoea).

  10. Analysis 1.5

    Analysis 1.5
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    Analysis 1.5

    Comparison 1 Rehabilitation versus usual care, Outcome 5 QoL - Change in SGRQ (Total).

  11. Analysis 1.6

    Analysis 1.6
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    Analysis 1.6

    Comparison 1 Rehabilitation versus usual care, Outcome 6 QoL - Change in SGRQ (Symptoms).

  12. Analysis 1.7

    Analysis 1.7
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    Analysis 1.7

    Comparison 1 Rehabilitation versus usual care, Outcome 7 QoL - Change in SGRQ (Impacts).

  13. Analysis 1.8

    Analysis 1.8
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    Analysis 1.8

    Comparison 1 Rehabilitation versus usual care, Outcome 8 QoL - Change in SGRQ (Activity).

  14. Analysis 1.9

    Analysis 1.9
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    Analysis 1.9

    Comparison 1 Rehabilitation versus usual care, Outcome 9 Maximal Exercise (Incremental shuttle walk test).

  15. Analysis 1.10

    Analysis 1.10
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    Analysis 1.10

    Comparison 1 Rehabilitation versus usual care, Outcome 10 Maximal Exercise Capacity (cycle ergometer).

  16. Analysis 1.11

    Analysis 1.11
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    Analysis 1.11

    Comparison 1 Rehabilitation versus usual care, Outcome 11 Functional Exercise Capacity (6MWT)).

  17. Analysis 2.1

    Analysis 2.1
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    Analysis 2.1

    Comparison 2 Rehabilitation versus usual care (subgroup analysis hospital vs community), Outcome 1 QoL - Change in CRQ (Fatigue).

  18. Analysis 2.2

    Analysis 2.2
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    Analysis 2.2

    Comparison 2 Rehabilitation versus usual care (subgroup analysis hospital vs community), Outcome 2 QoL - Change in CRQ (Emotional Function).

  19. Analysis 2.3

    Analysis 2.3
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    Analysis 2.3

    Comparison 2 Rehabilitation versus usual care (subgroup analysis hospital vs community), Outcome 3 QoL - Change in CRQ (Mastery).

  20. Analysis 2.4

    Analysis 2.4
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    Analysis 2.4

    Comparison 2 Rehabilitation versus usual care (subgroup analysis hospital vs community), Outcome 4 QoL - Change in CRQ (Dyspnoea).

  21. Analysis 2.5

    Analysis 2.5
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    Analysis 2.5

    Comparison 2 Rehabilitation versus usual care (subgroup analysis hospital vs community), Outcome 5 QoL - Change in SGRQ (Total).

  22. Analysis 2.6

    Analysis 2.6
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    Analysis 2.6

    Comparison 2 Rehabilitation versus usual care (subgroup analysis hospital vs community), Outcome 6 QoL - Change in SGRQ (Symptoms).

  23. Analysis 2.7

    Analysis 2.7
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    Analysis 2.7

    Comparison 2 Rehabilitation versus usual care (subgroup analysis hospital vs community), Outcome 7 QoL - Change in SGRQ (Impacts).

  24. Analysis 2.8

    Analysis 2.8
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    Analysis 2.8

    Comparison 2 Rehabilitation versus usual care (subgroup analysis hospital vs community), Outcome 8 QoL - Change in SGRQ (Activity).

  25. Analysis 3.1

    Analysis 3.1
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    Analysis 3.1

    Comparison 3 Rehabilitation versus usual care (subgroup analysis exercise only vs exercise and other), Outcome 1 QoL - Change in CRQ (Fatigue).

  26. Analysis 3.2

    Analysis 3.2
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    Analysis 3.2

    Comparison 3 Rehabilitation versus usual care (subgroup analysis exercise only vs exercise and other), Outcome 2 QoL - Change in CRQ (Emotional Function).

  27. Analysis 3.3

    Analysis 3.3
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    Analysis 3.3

    Comparison 3 Rehabilitation versus usual care (subgroup analysis exercise only vs exercise and other), Outcome 3 QoL - Change in CRQ (Mastery).

  28. Analysis 3.4

    Analysis 3.4
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    Analysis 3.4

    Comparison 3 Rehabilitation versus usual care (subgroup analysis exercise only vs exercise and other), Outcome 4 QoL - Change in CRQ (Dyspnoea).

  29. Analysis 3.5

    Analysis 3.5
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    Analysis 3.5

    Comparison 3 Rehabilitation versus usual care (subgroup analysis exercise only vs exercise and other), Outcome 5 QoL - Change in SGRQ (Total).

  30. Analysis 3.6

    Analysis 3.6
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    Analysis 3.6

    Comparison 3 Rehabilitation versus usual care (subgroup analysis exercise only vs exercise and other), Outcome 6 QoL - Change in SGRQ (Symptoms).

  31. Analysis 3.7

    Analysis 3.7
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    Analysis 3.7

    Comparison 3 Rehabilitation versus usual care (subgroup analysis exercise only vs exercise and other), Outcome 7 QoL - Change in SGRQ (Impacts).

  32. Analysis 3.8

    Analysis 3.8
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    Analysis 3.8

    Comparison 3 Rehabilitation versus usual care (subgroup analysis exercise only vs exercise and other), Outcome 8 QoL - Change in SGRQ (Activity).

  33. Analysis 4.1

    Analysis 4.1
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    Analysis 4.1

    Comparison 4 Rehabilitation versus usual care (sensitivity analysis by allocation concealment and incomplete outcome), Outcome 1 QoL - Change in CRQ (Dyspnoea).

  34. Analysis 4.2

    Analysis 4.2
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    Analysis 4.2

    Comparison 4 Rehabilitation versus usual care (sensitivity analysis by allocation concealment and incomplete outcome), Outcome 2 QoL - Change in CRQ (Emotional Function).

  35. Analysis 4.3

    Analysis 4.3
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    Analysis 4.3

    Comparison 4 Rehabilitation versus usual care (sensitivity analysis by allocation concealment and incomplete outcome), Outcome 3 QoL - Low Risk CRQ (Fatigue).

  36. Analysis 4.4

    Analysis 4.4
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    Analysis 4.4

    Comparison 4 Rehabilitation versus usual care (sensitivity analysis by allocation concealment and incomplete outcome), Outcome 4 QoL - Low Risk CRQ (Mastery).

  37. Analysis 4.5

    Analysis 4.5
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    Analysis 4.5

    Comparison 4 Rehabilitation versus usual care (sensitivity analysis by allocation concealment and incomplete outcome), Outcome 5 QoL - Low Risk SGRQ (Total).

  38. Analysis 4.6

    Analysis 4.6
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    Analysis 4.6

    Comparison 4 Rehabilitation versus usual care (sensitivity analysis by allocation concealment and incomplete outcome), Outcome 6 QoL - Low Risk SGRQ (Symptoms).

  39. Analysis 4.7

    Analysis 4.7
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    Analysis 4.7

    Comparison 4 Rehabilitation versus usual care (sensitivity analysis by allocation concealment and incomplete outcome), Outcome 7 QoL - Low Risk SGRQ (Impacts).

  40. Analysis 4.8

    Analysis 4.8
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    Analysis 4.8

    Comparison 4 Rehabilitation versus usual care (sensitivity analysis by allocation concealment and incomplete outcome), Outcome 8 QoL - Low Risk SGRQ (Activity).