Chapter 4.2 Crystallization of membrane proteins
Crystallography of biological macromolecules
Second Online Edition (2012)
Part 4. Crystallization
Published Online: 14 APR 2012
© International Union of Crystallography 2006
International Tables for Crystallography
How to Cite
Michel, H. 2012. Crystallization of membrane proteins. International Tables for Crystallography. F:4:4.2:122–128.
- Published Online: 14 APR 2012
The crystallization of membrane proteins is described. The topics covered include the principles of membrane‐protein crystallization, general properties of detergents relevant to membrane‐protein crystallization, the ‘small amphiphile concept’, membrane‐protein crystallization with the help of antibody Fv fragments and membrane‐protein crystallization using cubic bicontinuous lipidic phases. General recommendations on crystallizing membrane proteins are provided, and membrane proteins with known structures and potentially useful detergents are tabulated.
- antibody Fv fragments in crystallization of membrane proteins;
- cubic bicontinuous lipidic phases;
- membrane proteins;
- small amphiphile concept