Biotechnology and Bioengineering

Flagellin structure. The diagram of FliC tertiary structure was derived from its X-ray determined structure of flagellin (PDB ID 3A5X) and was drawn using the program PyMOL.

(A) Air-lift disposable bioreactor, (B) wave disposable bioreactor, and (C) schematic diagram of the dissolved oxygen control system for disposable bioreactor.

High frequency ultrasound microbeam mechanotransduction system: the system is comprised of a HFUMS system including a 200-MHz ultrasonic transducer for microbeam stimulation and an epi-fluorescence microscope for calcium imaging.

A: The cell support structure called MatriGrid® without cells. B: Cross-section of one microcavity with HepG2 cells. C: Schematic of the micro-bioreactor. D: micro-bioreactor used for the actively perfused three-dimensional cell cultivation.

Crystals from micro-batch experiments at 10°C using concentrated and dialyzed mAb01 harvest. Crystallization conditions were 5 mM histidine/acetate buffer, 10 mM NaCl, 6 mM TRIS base added, (A) 4.0 g L−1 mAb01, (B) 6.5 g L−1 mAb01. Microphotographs were taken after 24 h.

Schematic representation of (A) Cell-SELEX for aptamer selection against P. mirabilis and (B) in silico maturation for improvement of specificity of aptamers for P. mirabilis.