Biotechnology and Bioengineering

Cover image for Vol. 111 Issue 10

Edited By: Douglas S. Clark

Impact Factor: 4.164

ISI Journal Citation Reports © Ranking: 2013: 26/165 (Biotechnology & Applied Microbiology)

Online ISSN: 1097-0290

Featured

  • Modeling mechanical signals on the surface of µCT and CAD based rapid prototype scaffold models to predict (early stage) tissue development

    Modeling mechanical signals on the surface of µCT and CAD based rapid prototype scaffold models to predict (early stage) tissue development

    Derivation of models for FEA and CFD from (A) plotted scaffolds through rapid prototyping and (B) CAD scaffolds.

  • A versatile approach to the generation of fluid supported lipid bilayers and its applications

    A versatile approach to the generation of fluid supported lipid bilayers and its applications

    Engineering a PEG-supported cholesterol-rich (20%) DOPC bilayer. (a) Schematic depiction of the structure of the PEG-supported lipid bilayer with protein incorporated. (b) Fluorescence images of fluorescently labeled SLBs. (c) An example of a FRAP experiment that was performed on 5% PE-PEG to study mobility and fluidity of SLBs. (d) Immobile fractions of the bilayers formed at various PE-PEG/mPEG ratios are compared. While a 100% PE-PEG bilayer is largely fluid, its immobile fraction is considerably larger than with 5% PE-PEG.

  • A new method for generating high purity motoneurons from mouse embryonic stem cells

    A new method for generating high purity motoneurons from mouse embryonic stem cells

    Immunofluorescence staining of motoneurons sub-type markers. Following the 2−/4+ induction protocol and subsequent 24-h puromycin selection, cells were labeled with FoxP1 (red) and Lhx3 (green) to label distinct motor column identities in control (top) cultures and selected (bottom) cultures.

  • Improved lipid accumulation by morphology engineering of oleaginous fungus Mortierella isabellina

    Improved lipid accumulation by morphology engineering of oleaginous fungus Mortierella isabellina

    Effect of microparticle concentrations on spatial distribution of lipids within fungal pellets/mycelial aggregates.

  • Kinome profiling of osteoblasts on hydroxyapatite opens new avenues on biomaterial cell signaling

    Kinome profiling of osteoblasts on hydroxyapatite opens new avenues on biomaterial cell signaling

    Protein network depicting interactions among more phosphorylated substrates in HA and their interaction partners in associated pathways.

  • First pass intestinal and liver metabolism of paracetamol in a microfluidic platform coupled with a mathematical modeling as a means of evaluating ADME processes in humans

    First pass intestinal and liver metabolism of paracetamol in a microfluidic platform coupled with a mathematical modeling as a means of evaluating ADME processes in humans

    (A) Images of the IIDMP bioreactors; (B) principle of the bioreactors; (C) experimental procedures.

  • Modeling mechanical signals on the surface of µCT and CAD based rapid prototype scaffold models to predict (early stage) tissue development
  • A versatile approach to the generation of fluid supported lipid bilayers and its applications
  • A new method for generating high purity motoneurons from mouse embryonic stem cells
  • Improved lipid accumulation by morphology engineering of oleaginous fungus Mortierella isabellina
  • Kinome profiling of osteoblasts on hydroxyapatite opens new avenues on biomaterial cell signaling
  • First pass intestinal and liver metabolism of paracetamol in a microfluidic platform coupled with a mathematical modeling as a means of evaluating ADME processes in humans

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James E. Bailey Award

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Congratulations to B&B Editor-in-Chief Dr. Douglas S. Clark, 2014 recipient of the prestigious James E. Bailey Award from the Society for Biological Engineering.

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