Journal of Comparative Neurology
© Wiley Periodicals, Inc.
Edited By: PATRICK R. HOF
Impact Factor: 3.225
ISI Journal Citation Reports © Ranking: 2014: 5/154 (Zoology); 106/252 (Neurosciences)
Online ISSN: 1096-9861
JCN Antibody Database
Welcome to the JCN Antibody Database!
Clicking on the link below will allow you to download an Excel spreadsheet in which we have collected information on the antibodies used for immunohistochemistry by papers published in JCN from 2006 to present. It is organized alphabetically by the common name used for the antibody by the authors of the paper. Occasionally, different antibodies against the same target molecule may be listed under slightly different names. We recommend that the reader scan the list for alternate names for the target molecule that is to be identified. The list indicates which papers in JCN have used a particular antibody; more information on the antibodies can be found in those papers. The list will be updated every 3-4 months.
As of May, 2011, we have added a new feature to the Database. The Neuroscience Information Framework (http://www.neuinfo.org/) is systematically cataloguing antibodies, and we are cooperating with them, as our database on papers that characterize antibodies is the most extensive documentation available. They have provided their registry number (Antibody ID from NIF), and a link to the text for that antibody in their registry. They have also added the PubMed ID numbers for all of our papers for each antibody, which will make it easier for users of both their database and ours to look up the original JCN papers in PubMed.
The reason for presenting this list is that JCN has had a policy since 2006 on requiring rigorous characterization for all antibodies that are used in our papers (see our editorial on this subject). The antibodies on the list have in (nearly*) all cases been described and characterized adequately according to these guidelines, at least for the purpose for which the antibody was used in that paper. Note that using an antibody for a different purpose may require a more rigorous characterization; this can be determined only on a case by case basis, however. Nevertheless, if you are looking for an antibody to identify a particular target immunohistochemically, this list is a good place to begin your search. We suggest you then look up the paper in which the antibody was used, to make sure that it will meet your needs and to verify its characterization. (The characterization of antibodies in JCN papers often goes well beyond the material published by the manufacturer, so that examining this information before you order an antibody can be very useful.) While we do not guarantee that these antibodies will identify only the intended target (that is a function of the actual experiment and controls), this is the most carefully verified list of antibodies that we are aware of, and we wanted to share this resource with our readers and authors.
*This policy is enforced by our editors, who are humans and occasionally do make errors, and let through an occasional antibody with insufficient information. We apologize to users who encounter these rare events. However, our goal is to avoid such errors, and hence if you do use one of these antibodies in your own work, we will insist on appropriate characterization in any future papers.