Recommendations for a step-wise comparative approach to the evaluation of new screening tests for colorectal cancer
Graeme P. Young, Carlo Senore, Jack S. Mandel, James E. Allison, Wendy S. Atkin, Robert Benamouzig, Patrick M. M. Bossuyt, Mahinda De Silva, Lydia Guittet, Stephen P. Halloran, Ulrike Haug, Geir Hoff, Steven H. Itzkowitz, Marcis Leja, Bernard Levin, Gerrit A. Meijer, Colm A. O'Morain, Susan Parry, Linda Rabeneck, Paul Rozen, Hiroshi Saito, Robert E. Schoen, Helen E. Seaman, Robert J. C. Steele, Joseph J. Y. Sung and Sidney J. Winawer
Article first published online: 1 FEB 2016 | DOI: 10.1002/cncr.29865
To provide practical guidance on how to compare new screening tests with proven screening tests for colorectal cancer, a panel of experts reviews the literature and proposes a 4-phase evaluation process that includes comparison with existing, proven tests but does not necessarily require randomized controlled trials with mortality as the endpoint. New screening tests can be evaluated efficiently using this stepwise comparative approach.