Pathologic and gene expression features of metastatic melanomas to the brainRonald Hamilton, Michal Krauze, Marjorie Romkes, Bernard Omolo, Panagiotis Konstantinopoulos, Todd Reinhart, Malgorzata Harasymczuk, YangYang Wang, Yan Lin, Soldano Ferrone, Theresa Whiteside, Stephanie Bortoluzzi, Jonette Werley, Tomoko Nukui, Beth Fallert-Junecko, Douglas Kondziolka, Joseph Ibrahim, Dorothea Becker, John Kirkwood and Stergios Moschos
Article first published online: 21 MAY 2013 | DOI: 10.1002/cncr.28029
Metastatic melanomas to the brain are more similar to extracranial metastases compared with primary melanomas. Metastatic melanoma to the brain has a variable prognosis: low or absent intratumoral hemorrhage and high mononuclear infiltrate define a subgroup with favorable prognosis.