Clinical and pathologic features of familial pancreatic cancer
Jeremy L. Humphris, Amber L. Johns, Skye H. Simpson, Mark J. Cowley, Marina Pajic, David K. Chang, Adnan M. Nagrial, Venessa T. Chin, Lorraine A. Chantrill, Mark Pinese, R. Scott Mead, Anthony J. Gill, Jaswinder S. Samra, James G. Kench, Elizabeth A. Musgrove, Katherine M. Tucker, Allan D. Spigelman, Nic Waddell, Sean M. Grimmond, Andrew V. Biankin and the Australian Pancreatic Cancer Genome Initiative
Article first published online: 14 OCT 2014 | DOI: 10.1002/cncr.28863
The risk of malignancy in familial pancreatic cancer (PC) kindreds does not appear to be confined to the pancreas. Patients with familial PC have more precursor lesions, smoker less, and have lower tobacco exposure but are similar in age at diagnosis and outcome compared with patients who have sporadic PC.