International Journal of Cancer

Cover image for Vol. 133 Issue 3

Accepted Articles (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)

Editor-in-Chief: Professor Peter Lichter, DKFZ, Germany

Impact Factor: 5.444

ISI Journal Citation Reports © Ranking: 2011: 27/196 (Oncology)

Online ISSN: 1097-0215

  1. Early Detection and Diagnosis

    1. Using microRNA profiling in urine samples to develop a non-invasive test for bladder cancer

      Lourdes Mengual, Juan José Lozano, Mercedes Ingelmo-Torres, Cristina Gazquez, María José Ribal and Antonio Alcaraz

      Accepted manuscript online: 17 MAY 2013 10:26PM EST | DOI: 10.1002/ijc.28274

  2. Cancer Cell Biology

    1. p14ARF induces apoptosis via an entirely caspase-3 dependent mitochondrial amplification loop

      Ana Milojkovic, Philipp G. Hemmati, Annika Müer, Tim Overkamp, Cindrilla Chumduri, Reiner U. Jänicke, Bernd Gillissen and Peter T. Daniel

      Accepted manuscript online: 17 MAY 2013 10:24PM EST | DOI: 10.1002/ijc.28279

  3. Early Detection and Diagnosis

    1. Unbalanced estrogen metabolism in thyroid cancer

      Muhammad Zahid, Whitney Goldner, Cheryl L. Beseler, Eleanor G. Rogan and Ercole L. Cavalieri

      Accepted manuscript online: 17 MAY 2013 10:22PM EST | DOI: 10.1002/ijc.28275

  4. Cancer Cell Biology

    1. Silencing the mannose 6-phosphate/IGF-II receptor differentially affects tumorigenic properties of normal breast epithelial cells

      Nicole J Caixeiro, Janet L Martin and Carolyn D Scott

      Accepted manuscript online: 17 MAY 2013 10:21PM EST | DOI: 10.1002/ijc.28276

  5. Cancer Therapy

    1. CD34+/CD38- acute myelogenous leukemia cells aberrantly express aurora kinase A

      Jing Yang, Takayuki Ikezoe, Chie Nishioka, Atsuya Nobumoto, Keiko Udaka and Akihito Yokoyama

      Accepted manuscript online: 17 MAY 2013 10:21PM EST | DOI: 10.1002/ijc.28277

  6. Tumor Immunology

    1. Macrophages in T cell/histiocyte rich large B cell lymphoma strongly express metal-binding proteins and show a bi-activated phenotype

      Sylvia Hartmann, Thomas Tousseyn, Claudia Döring, Patricia Flüchter, Holger Hackstein, An Herreman, Maurilio Ponzoni, Chris de Wolf-Peeters, Fabio Facchetti, Randy D. Gascoyne, Ralf Küppers, Christian Steidl and Martin-Leo Hansmann

      Accepted manuscript online: 17 MAY 2013 10:21PM EST | DOI: 10.1002/ijc.28273

  7. Carcinogenesis

    1. Heterogeneous expression and functional relevance of the ubiquitin carboxyl-terminal hydrolase L1 in melanoma

      Jens Wulfänger, Katharina Biehl, Anja Tetzner, Peter Wild, Kristian Ikenberg, Stefanie Meyer and Barbara Seliger

      Accepted manuscript online: 17 MAY 2013 10:19PM EST | DOI: 10.1002/ijc.28278

  8. Cancer Cell Biology

    1. Contribution of ADAMTS1 as a tumor suppressor gene in human breast carcinoma. Linking its tumor inhibitory properties to its proteolytic activity on Nidogen-1 and Nidogen-2

      Estefanía Martino-Echarri, Rubén Fernández-Rodríguez, Francisco Javier Rodríguez-Baena, Antonio Barrientos-Durán, Antoni X. Torres-Collado, María del Carmen Plaza-Calonge, Suyapa Amador-Cubero, Javier Cortés, Louise E. Reynolds, Kairbaan M. Hodivala-Dilke and Juan Carlos Rodríguez-Manzaneque

      Accepted manuscript online: 16 MAY 2013 02:32AM EST | DOI: 10.1002/ijc.28271

    2. Induction of CaSR expression circumvents the molecular features of malignant CaSR null colon cancer cells

      Navneet Singh and Subhas Chakrabarty

      Accepted manuscript online: 15 MAY 2013 03:51AM EST | DOI: 10.1002/ijc.28270

  9. Epidemiology

    1. A prospective analysis of telomere length and pancreatic cancer in the Alpha-Tocopherol Beta-Carotene cancer prevention (ATBC) study

      Shannon M. Lynch, Jacqueline M. Major, Richard Cawthon, Stephanie J. Weinstein, Jarmo Virtamo, Qing Lan, Nathaniel Rothman, Demetrius Albanes and Rachael Z. Stolzenberg-Solomon

      Accepted manuscript online: 15 MAY 2013 03:51AM EST | DOI: 10.1002/ijc.28272

  10. Tumor Immunology

    1. Endothelial plasticity governs the site-specific leukocyte recruitment in hepatocellular cancer

      Olga Salnikova, Kai Breuhahn, Natalie Hartmann, Jan Schmidt and Eduard Ryschich

      Accepted manuscript online: 10 MAY 2013 03:59AM EST | DOI: 10.1002/ijc.28268

  11. Early Detection and Diagnosis

    1. CD133 expression in circulating tumor cells from breast cancer patients: Potential role in resistance to chemotherapy

      Rosa Nadal, F.Gabriel Ortega, Marta Salido, Jose A. Lorente, Maria Rodríguez-Rivera, Miguel Delgado-Rodríguez, Marta Macià, Ana Fernández, Josep M. Corominas, J.Luis García-Puche, Pedro Sánchez-Rovira, Francesc Solé and M. Jose Serrano

      Accepted manuscript online: 10 MAY 2013 03:58AM EST | DOI: 10.1002/ijc.28263

  12. Short Reports

    1. Tumor necrosis factor alpha induced warburg-like metabolism and is reversed by anti-inflammatory curcumin in breast epithelial cells

      Roger A. Vaughan, Randi Garcia-Smith, Jonathan Dorsey, Jeffrey K. Griffith, Marco Bisoffi and Kristina A. Trujillo

      Accepted manuscript online: 10 MAY 2013 01:59AM EST | DOI: 10.1002/ijc.28264

  13. Tumor Immunology

    1. αv-Integrin isoform expression in primary human tumors and brain metastases

      Alexander Vogetseder, Svenja Thies, Barbara Ingold, Patrick Roth, Michael Weller, Peter Schraml, Simon L. Goodman and Holger Moch

      Accepted manuscript online: 10 MAY 2013 01:55AM EST | DOI: 10.1002/ijc.28267

  14. Infectious Causes of Cancer

    1. Frequent detection of human cytomegalovirus in neuroblastoma: A novel therapeutic target?

      Nina Wolmer-Solberg, Ninib Baryawno, Afsar Rahbar, Dieter Fuchs, Jenny Odeberg, Chato Taher, Vanessa Wilhelmi, Jelena Milosevic, Abdul-Aleem Mohammad, Tommy Martinsson, Baldur Sveinbjörnsson, John Inge Johnsen, Per Kogner and Cecilia Söderberg-Nauclér

      Accepted manuscript online: 10 MAY 2013 01:43AM EST | DOI: 10.1002/ijc.28265

  15. Cancer Therapy

  16. Epidemiology

    1. Familial risk of childhood cancer and tumors in the Li-Fraumeni spectrum in the Utah population database: Implications for genetic evaluation in pediatric practice

      Karen Curtin, Ken R. Smith, Alison Fraser, Richard Pimentel, Wendy Kohlmann and Joshua D. Schiffman

      Accepted manuscript online: 10 MAY 2013 01:31AM EST | DOI: 10.1002/ijc.28266

  17. Short Reports

    1. Long term treatment with Sitagliptin, a dipeptidyl peptidase-4 inhibitor, reduces colon carcinogenesis and reactive oxygen species in 1,2-dimethylhydrazine-induced rats

      Angelo Pietro Femia, Laura Raimondi, Giulia Maglieri, Maura Lodovici, Edoardo Mannucci and Giovanna Caderni

      Accepted manuscript online: 7 MAY 2013 04:16AM EST | DOI: 10.1002/ijc.28260

  18. Mini Reviews

    1. Molecular targeted agents (MTA) combination therapy for cancer: Developments and potentials

      Feifei Li, Changqi Zhao and Lili Wang

      Accepted manuscript online: 7 MAY 2013 04:16AM EST | DOI: 10.1002/ijc.28261

  19. Cancer Therapy

    1. Estrogen and insulin-like growth factor synergistically promote the development of lung adenocarcinoma in mice

      Hexiao Tang, Yongde Liao, Liqiang Xu, Chao Zhang, Zhaoguo Liu, Yu Deng, Zhixiao Jiang, Shengling Fu, Zhenguang Chen and Sheng Zhou

      Accepted manuscript online: 7 MAY 2013 04:11AM EST | DOI: 10.1002/ijc.28262

    2. Metronomic chemotherapy following the maximum tolerated dose is an effective anti-tumour therapy affecting angiogenesis, tumour dissemination and cancer stem cells

      M. Vives, M. M. Ginestà, K. Gracova, M. Graupera, O. Casanovas, G. Capellà, T. Serrano, B. Laquente and F. Viñals

      Accepted manuscript online: 7 MAY 2013 04:04AM EST | DOI: 10.1002/ijc.28259

  20. Epidemiology

    1. Dietary flavonoid, lignan and antioxidant capacity and risk of hepatocellular carcinoma in the european prospective investigation into cancer and nutrition (EPIC) study

      Raul Zamora-Ros, Veronika Fedirko, Antonia Trichopoulou, Carlos A. González, Christina Bamia, Elisabeth Trepo, Ute Nöthlings, Talita Duarte-Salles, Mauro Serafini, Lea Bredsdorff, Kim Overvad, Anne Tjønneland, Jytte Halkjær, Guy Fagherazzi, Florence Perquier, Marie-Christine Boutron-Ruault, Verena Katzke, Annekatrin Lukanova, Anna Floegel, Heiner Boeing, Pagona Lagiou, Dimitrios Trichopoulos, Calogero Saieva, Claudia Agnoli, Amalia Mattiello, Rosario Tumino, Carlotta Sacerdote, H. Bas Bueno-de-Mesquita, Petra M. Peeters, Elisabete Weiderpass, Dagrun Engeset, Guri Skeie, Marcial Vicente Argüelles, Esther Molina-Montes, Miren Dorronsoro, María José Tormo, Eva Ardanaz, Ulrika Ericson, Emily Sonestedt, Malin Sund, Rikard Landberg, Kay-Tee Khaw, Nicholas J. Wareham, Francesca L. Crowe, Elio Riboli and Mazda Jenab

      Accepted manuscript online: 6 MAY 2013 05:14AM EST | DOI: 10.1002/ijc.28257

  21. Cancer Cell Biology

    1. The metastatic microenvironment: Lung-derived factors control the viability of neuroblastoma lung metastasis

      Shelly Maman, Liat Edry-Botzer, Orit Sagi-Assif, Tsipi Meshel, Weirong Yuan, Wuyuan Lu and Isaac P. Witz

      Accepted manuscript online: 6 MAY 2013 12:08AM EST | DOI: 10.1002/ijc.28255

  22. Early Detection and Diagnosis

    1. Modelling the benefits of early diagnosis of pancreatic cancer using a biomarker signature

      Ola Ghatnekar, Roland Andersson, Marianne Svensson, Ulf Persson, Ulrika Ringdahl, Paula Zeilon and Carl A.K. Borrebaeck

      Accepted manuscript online: 6 MAY 2013 12:01AM EST | DOI: 10.1002/ijc.28256

  23. Cancer Therapy

    1. MicroRNA profiling in locally advanced esophageal cancer indicates a high potential of miR-192 in prediction of multimodality therapy response

      M. Odenthal, E. Bollschweiler, P.P. Grimminger, W. Schröder, J. Brabender, U. Drebber, A.H. Hölscher, R. Metzger and D. Vallböhmer

      Accepted manuscript online: 3 MAY 2013 01:50PM EST | DOI: 10.1002/ijc.28253

  24. Letters to the Editor

    1. Failure to account for selection-bias

      Mette Kalager, Magnus Løberg, Vinjar M. Fønnebø and Michael Bretthauer

      Accepted manuscript online: 3 MAY 2013 01:49PM EST | DOI: 10.1002/ijc.28244

  25. Mini Reviews

    1. The receptor tyrosine kinase Axl in cancer: Biological functions and therapeutic implications

      Juliano D. Paccez, Matjaz Vogelsang, M. Iqbal Parker and Luiz F. Zerbini

      Accepted manuscript online: 3 MAY 2013 11:50AM EST | DOI: 10.1002/ijc.28246

  26. Letters to the Editor

    1. Response to comments

      Ragnhild Sørum Falk, Solveig Hofvind, Per Skaane and Tor Haldorsen

      Accepted manuscript online: 3 MAY 2013 11:50AM EST | DOI: 10.1002/ijc.28247

  27. Short Reports

    1. Mortality risk in former smokers with breast cancer: Pack-years vs. smoking status

      Nazmus Saquib, Marcia L. Stefanick, Loki Natarajan and John P. Pierce

      Accepted manuscript online: 3 MAY 2013 11:41AM EST | DOI: 10.1002/ijc.28241

  28. Epidemiology

    1. Tubal ligation, hysterectomy, and epithelial ovarian cancer in the New England case-control study

      Megan S. Rice, Megan A. Murphy, Allison F. Vitonis, Daniel W. Cramer, Linda J. Titus, Shelley S. Tworoger and Kathryn L. Terry

      Accepted manuscript online: 3 MAY 2013 11:40AM EST | DOI: 10.1002/ijc.28249

  29. Letters to the Editor

    1. Overdiagnosis of breast cancer in Norway: What have the authors adjusted for?

      Per-Henrik Zahl, Pål Suhrke and Karsten Juhl Jørgensen

      Accepted manuscript online: 3 MAY 2013 11:37AM EST | DOI: 10.1002/ijc.28248

    2. Explaining sex difference in cancer risk: Might it be related to excess iron?

      Luca Mascitelli and Mark R. Goldstein

      Accepted manuscript online: 3 MAY 2013 11:36AM EST | DOI: 10.1002/ijc.28240

  30. Epidemiology

    1. Risk factors for false positive and for false negative test results in screening with fecal occult blood testing

      Inge Stegeman, Thomas R. de Wijkerslooth, Esther M. Stoop, Monique van Leerdam, M. van Ballegooijen, Roderik A. Kraaijenhagen, Paul Fockens, Ernst J. Kuipers, Evelien Dekker and Patrick M. Bossuyt

      Accepted manuscript online: 3 MAY 2013 11:36AM EST | DOI: 10.1002/ijc.28242

  31. Early Detection and Diagnosis

    1. Molecular diagnosis of endometrial cancer from uterine aspirates

      Cristina Perez-Sanchez, Eva Colas, Silvia Cabrera, Orlando Falcon, Angel Sanchez-del-Río, Enrique García, Luis Fernández-de-Castillo, Juan Carlos Muruzabal, Elena Alvarez, Gabriel Fiol, Carmen González, Rafael Torrejón, Eloy Moral, Miriam Campos, Manuel Repollés, Ramon Carreras, Jesus Jiménez-López, Jordi Xercavins, Elena Aibar, Alvaro Perdones-Montero, Eric Lalanne, Marta Palicio, Tamara Maes, Elisabet Rosell-Vives, Carlos Nieto, Alicia Ortega, Nuria Pedrola, Marta Llauradó, Marina Rigau, Andreas Doll, Miguel Abal, Jordi Ponce, Antonio Gil-Moreno and Jaume Reventós

      Accepted manuscript online: 3 MAY 2013 11:31AM EST | DOI: 10.1002/ijc.28243

  32. Epidemiology

    1. A population-based prospective study of energy-providing nutrients in relation to cancer mortality and cancers of digestive organs mortality

      Maria Argos, Stephanie Melkonian, Faruque Parvez, Muhammad Rakibuz-Zaman, Alauddin Ahmed, Yu Chen and Habibul Ahsan

      Accepted manuscript online: 3 MAY 2013 11:30AM EST | DOI: 10.1002/ijc.28250

  33. Cancer Genetics

    1. Matriptase-2 gene (TMPRSS6) variants associate with breast cancer survival, and reduced expression is related to triple-negative breast cancer

      Hanna Tuhkanen, Jaana M. Hartikainen, Ylermi Soini, Gloria Velasco, Reijo Sironen, Timo K. Nykopp, Vesa Kataja, Veli-Matti Kosma and Arto Mannermaa

      Accepted manuscript online: 3 MAY 2013 11:30AM EST | DOI: 10.1002/ijc.28254

    2. Genetic variants in C-type lectin genes are associated with colorectal cancer susceptibility and clinical outcome

      Shun Lu, Melanie Bevier, Stefanie Huhn, Juan Sainz, Jesus Lascorz, Barbara Pardini, Alessio Naccarati, Ludmila Vodickova, Jan Novotny, Kari Hemminki, Pavel Vodicka and Asta Försti

      Accepted manuscript online: 3 MAY 2013 11:30AM EST | DOI: 10.1002/ijc.28251

  34. Cancer Cell Biology

    1. Characterization of CACNA2D3 as a putative tumor suppressor gene in the development and progression of nasopharyngeal carcinoma

      Alissa Michelle Go Wong, Kar Lok Kong, Leilei Chen, Ming Liu, Aikha Melissa Go Wong, Cailei Zhu, Janice Wing-hang Tsang and Xin-Yuan Guan

      Accepted manuscript online: 3 MAY 2013 11:25AM EST | DOI: 10.1002/ijc.28252

  35. Cancer Genetics

    1. Ataxia-telangiectasia mutated (ATM) protein expression with microsatellite instability in gastric cancer as prognostic marker

      Jin Won Kim, Seock-Ah Im, Min A Kim, Hyun Jin Cho, Dae Won Lee, Kyung-Hun Lee, Tae-Yong Kim, Sae-Won Han, Do-Youn Oh, Hyuk-Joon Lee, Tae-You Kim, Han-Kwang Yang, Woo Ho Kim and Yung-Jue Bang

      Accepted manuscript online: 3 MAY 2013 11:25AM EST | DOI: 10.1002/ijc.28245

  36. Infectious Causes of Cancer

    1. Early gene expression changes by Epstein-Barr virus infection of B-cells indicate CDKs and survivin as therapeutic targets for post-transplant lymphoproliferative diseases

      Michele Bernasconi, Seigo Ueda, Patricia Krukowski, Beat C. Bornhauser, Kristin Ladell, Marcus Dorner, Juerg A. Sigrist, Cristina Campidelli, Roberta Aslandogmus, Davide Alessi, Christoph Berger, Stefano A. Pileri, Roberto F. Speck and David Nadal

      Accepted manuscript online: 2 MAY 2013 07:34AM EST | DOI: 10.1002/ijc.28239

  37. Cancer Genetics

    1. Identification of hepatic microvascular adhesion-related genes of human colon cancer cells using random homozygous gene perturbation

      Joana Márquez, Manu Kohli, Beatriz Arteta, Shaojing Chang, Wu-Bo Li, Michael Goldblatt and Fernando Vidal-Vanaclocha

      Accepted manuscript online: 30 APR 2013 02:31AM EST | DOI: 10.1002/ijc.28232

  38. Cancer Cell Biology

    1. Antitumor activity of pimasertib, a selective MEK 1/2 inhibitor, in combination with PI3K/mTOR inhibitors or with multi-targeted kinase inhibitors in pimasertib-resistant human lung and colorectal cancer cells

      Erika Martinelli, Teresa Troiani, Elena D'Aiuto, Floriana Morgillo, Donata Vitagliano, Anna Capasso, Sara Costantino, Loreta Pia Ciuffreda, Francesco Merolla, Loredana Vecchione, Veerle De Vriendt, Sabine Tejpar, Anna Nappi, Vincenzo Sforza, Giulia Martini, Liberato Berrino, Raffaele De Palma and Fortunato Ciardiello

      Accepted manuscript online: 30 APR 2013 01:37AM EST | DOI: 10.1002/ijc.28236

    2. Cathepsin S from both tumour and tumour-associated cells promote cancer growth and neovascularisation

      Donna M Small, Roberta E Burden, Jakub Jaworski, Shauna M Hegarty, Shaun Spence, James F Burrows, Cheryl McFarlane, Adrien Kissenpfennig, Helen O McCarthy, James A Johnston, Brian Walker and Christopher J Scott

      Accepted manuscript online: 30 APR 2013 12:21AM EST | DOI: 10.1002/ijc.28238

  39. Epidemiology

    1. Evaluation of genetic variants in microRNA biosynthesis genes and risk of breast cancer in Chinese women

      Yue Jiang, Jiaping Chen, Jiangping Wu, Zhibin Hu, Zhenzhen Qin, Xiao'an Liu, Xiaoxiang Guan, Yanru Wang, Jing Han, Tao Jiang, Guangfu Jin, Mingfeng Zhang, Hongxia Ma, Shui Wang and Hongbing Shen

      Accepted manuscript online: 30 APR 2013 12:08AM EST | DOI: 10.1002/ijc.28237

  40. Cancer Therapy

    1. Cardiac toxicity in breast cancer patients treated with dual HER2 blockade

      Antonis Valachis, Andreas Nearchou, Nikolaos P Polyzos and Pehr Lind

      Accepted manuscript online: 30 APR 2013 12:07AM EST | DOI: 10.1002/ijc.28234

  41. Cancer Genetics

    1. Synthetic sickness or lethality points at candidate combination therapy targets in glioblastoma

      Ewa Szczurek, Navodit Misra and Martin Vingron

      Accepted manuscript online: 30 APR 2013 12:00AM EST | DOI: 10.1002/ijc.28235

  42. Tumor Immunology

    1. Antitumor T cell responses in bladder cancer are directed against a limited set of antigens and are modulated by regulatory T cells and routine treatment approaches

      Thomas Horn, Jessica Grab, Julia Schusdziarra, Sebastian Schmid, Tobias Maurer, Roman Nawroth, Petra Wolf, Maria Pritsch, Jürgen E. Gschwend, Hubert R. Kübler and Philipp Beckhove

      Accepted manuscript online: 27 APR 2013 10:46AM EST | DOI: 10.1002/ijc.28233

  43. Short Reports

    1. Anal and perianal squamous carcinomas and high-grade intraepithelial lesions exclusively associated with “low-risk” HPV genotypes 6 and 11

      Alyssa M. Cornall, Jennifer Roberts, Suzanne M. Garland, Richard J. Hillman, Andrew E. Grulich and Sepehr N. Tabrizi

      Accepted manuscript online: 24 APR 2013 06:11PM EST | DOI: 10.1002/ijc.28228

  44. Early Detection and Diagnosis

    1. Screening for occult malignancy with FDG-PET/CT in patients with unprovoked venous thromboembolism

      Ana Alfonso, Margarita Redondo, Tomás Rubio, Beatriz Del Olmo, Pablo Rodríguez-Wilhelmi, María J. García Velloso, José A. Richter, José A. Páramo and Ramón Lecumberri

      Accepted manuscript online: 24 APR 2013 05:41PM EST | DOI: 10.1002/ijc.28229

    2. Presence of EpCAM-positive circulating tumor cells as biomarker for systemic disease strongly correlates to survival in patients with hepatocellular carcinoma

      Kornelius Schulze, Christin Gasch, Katharina Staufer, Björn Nashan, Ansgar W. Lohse, Klaus Pantel, Sabine Riethdorf and Henning Wege

      Accepted manuscript online: 24 APR 2013 05:17PM EST | DOI: 10.1002/ijc.28230

  45. Epidemiology

    1. Survival among adolescents and young adults with cancer in Germany and the United States: An international comparison

      Adam Gondos, Eva Hiripi, Bernd Holleczek, Sabine Luttmann, Andrea Eberle and Hermann Brenner, Members of the German GEKID Cancer Survival Working Group

      Accepted manuscript online: 24 APR 2013 04:40PM EST | DOI: 10.1002/ijc.28231

    2. Divergent estrogen receptor positive and negative breast cancer trends and etiologic heterogeneity in Denmark

      William F. Anderson, Philip S. Rosenberg, Lucia Petito, Hormuzd A. Katki, Bent Ejlertsen, Marianne Ewertz D, Birgitte B. Rasmussen, Maj-Britt Jensen and Niels Kroman

      Accepted manuscript online: 24 APR 2013 09:45AM EST | DOI: 10.1002/ijc.28222

  46. Carcinogenesis

    1. Methylation-mediated repression of GADD45A and GADD45G expression in gastric cardia adenocarcinoma

      Wei Guo, Zhiming Dong, Yanli Guo, Zhifeng Chen, Gang Kuang and Zhibin Yang

      Accepted manuscript online: 24 APR 2013 09:42AM EST | DOI: 10.1002/ijc.28223

  47. Letters to the Editor

    1. Development of diffuse carcinomas in the gastric corpus in patients with rugal hyperplastic gastritis

      Reidar Fossmark and Helge Waldum

      Accepted manuscript online: 23 APR 2013 04:35PM EST | DOI: 10.1002/ijc.28227

  48. Mini Reviews

    1. Roles of Chk1 in cell biology and cancer therapy

      Youwei Zhangand and Tony Hunter

      Accepted manuscript online: 23 APR 2013 04:35PM EST | DOI: 10.1002/ijc.28226

  49. Letters to the Editor

    1. Re: Development of diffuse carcinoma in the gastric corpus in patients with rugal hyperplastic gastritis

      Masao Ichinose, Mika Watanabe and Jun Kato

      Accepted manuscript online: 23 APR 2013 04:35PM EST | DOI: 10.1002/ijc.28225

  50. Carcinogenesis

    1. Dietary selenium supplementation modifies breast tumor growth and metastasis

      Yu-Chi Chen, K. Sandeep Prabhu, Arunangshu Das and Andrea M. Mastro

      Accepted manuscript online: 23 APR 2013 04:33PM EST | DOI: 10.1002/ijc.28224

  51. Cancer Therapy

    1. Utilization of genomic signatures to identify high efficacy candidate drugs for chemo-refractory endometrial cancers

      Budiman Kharma, Tsukasa Baba, Masaki Mandai, Noriomi Matsumura, Susan K. Murphy, Hyun Sook Kang, Koji Yamanoi, Junzo Hamanishi, Ken Yamaguchi, Yumiko Yoshioka and Ikuo Konishi

      Accepted manuscript online: 18 APR 2013 03:30AM EST | DOI: 10.1002/ijc.28220

  52. Epidemiology

    1. How much of the deprivation gap in cancer survival can be explained by variation in stage at diagnosis: An example from breast cancer in the East of England

      MJ Rutherford, SR Hinchliffe, GA Abel, G Lyratzopoulos, PC Lambert and DC Greenberg

      Accepted manuscript online: 18 APR 2013 03:30AM EST | DOI: 10.1002/ijc.28221

  53. Cancer Cell Biology

  54. Carcinogenesis

    1. Changes in aberrant DNA methylation after helicobacter pylori eradication: A long-term follow-up study

      Cheol Min Shin, Nayoung Kim, Hye Seung Lee, Ji Hyun Park, Soyeon Ahn, Gyeong Hoon Kang, Jung Mogg Kim, Joo Sung Kim, Dong Ho Lee and Hyun Chae Jung

      Accepted manuscript online: 18 APR 2013 03:30AM EST | DOI: 10.1002/ijc.28219

  55. Epidemiology

    1. Occupational exposure to arsenic and risk of non-melanoma skin cancer in a multinational European study

      Simona Surdu, Edward F. Fitzgerald, Michael S. Bloom, Francis P. Boscoe, David O. Carpenter, Richard F. Haase, Eugen Gurzau, Peter Rudnai, Kvetoslava Koppova, Joëlle Févotte, Marie Vahter, Giovanni Leonardi, Walter Goessler, Rajiv Kumar and Tony Fletcher

      Accepted manuscript online: 18 APR 2013 03:30AM EST | DOI: 10.1002/ijc.28216

  56. Tumor Immunology

    1. Human Vγ2Vδ2 T cells limit breast cancer growth by modulating cell survival-, apoptosis-related molecules, and microenvironment in tumors

      Reeva Aggarwal, Jingwei Lu, Suman Kanji, Manjusri Das, Matthew Joseph, Maryam B. Lustberg, Alo Ray, Vincent J. Pompili, Charles L. Shapiro and Hiranmoy Das

      Accepted manuscript online: 18 APR 2013 03:30AM EST | DOI: 10.1002/ijc.28217

  57. Carcinogenesis

    1. Comparison of in vitro and in vivo biological effects of trabectedin, lurbinectedin (PM01183) and Zalypsis® (PM00104)

      Michela Romano, Roberta Frapolli, Monique Zangarini, Ezia Bello, Luca Porcu, Carlos M. Galmarini, Luis F. García-Fernández, Carmen Cuevas, Paola Allavena, Eugenio Erba and Maurizio D'Incalci

      Accepted manuscript online: 16 APR 2013 04:15AM EST | DOI: 10.1002/ijc.28213

  58. Cancer Cell Biology

    1. Combined targeting of AKT and mTOR using MK-2206 and RAD001 is synergistic in the treatment of cholangiocarcinoma

      Florian Ewald, Nicole Grabinski, Astrid Grottke, Sabine Windhorst, Dominik Nörz, Lisa Carstensen, Katharina Staufer, Bianca T. Hofmann, Frank Diehl, Kerstin David, Udo Schumacher, Björn Nashan and Manfred Jücker

      Accepted manuscript online: 16 APR 2013 04:15AM EST | DOI: 10.1002/ijc.28214

  59. Epidemiology

    1. Natural immune responses against eight oncogenic human papillomaviruses in the ASCUS-LSIL triage study

      Lauren E. Wilson, Michael Pawlita, Phillip E. Castle, Tim Waterboer, Vikrant Sahasrabuddhe, Patti E. Gravitt, Mark Schiffman and Nicolas Wentzensen

      Accepted manuscript online: 15 APR 2013 11:08AM EST | DOI: 10.1002/ijc.28215

    2. Association between physical activity and mortality in colorectal cancer: A Meta-analysis of prospective cohort studies

      Youjin Je, Justin Y. Jeon, Edward L. Giovannucci and Jeffrey A. Meyerhardt

      Accepted manuscript online: 12 APR 2013 04:07AM EST | DOI: 10.1002/ijc.28208

  60. Cancer Cell Biology

    1. Concurrent inhibition of PI3K and mTORC1/mTORC2 overcomes resistance to rapamycin induced apoptosis by down-regulation of Mcl-1 in mantle cell lymphoma

      Anja Müller, Chuanbing Zang, Cindrilla Chumduri, Bernd Dörken, Peter T. Daniel and Christian W. Scholz

      Accepted manuscript online: 12 APR 2013 04:07AM EST | DOI: 10.1002/ijc.28206

  61. Epidemiology

    1. Childhood infectious diseases and risk of leukaemia in an adult population

      Stefano Parodi, Paolo Crosignani, Lucia Miligi, Oriana Nanni, Valerio Ramazzotti, Stefania Rodella, Adele Seniori Costantini, Rosario Tumino, Carla Vindigni, Paolo Vineis and Emanuele Stagnaro

      Accepted manuscript online: 11 APR 2013 02:31AM EST | DOI: 10.1002/ijc.28205

  62. Mini Reviews

    1. Comparative epidemiology of HPV infection and associated cancers of the head and neck and cervix

      Maura L Gillison, Xavier Castellsagué, Anil Chaturvedi, Marc T. Goodman, Peter Snijders, Massimo Tommasino, Marc Arbyn and Silvia Franceschi

      Accepted manuscript online: 9 APR 2013 04:07AM EST | DOI: 10.1002/ijc.28201

  63. Cancer Therapy

    1. Pyrimethamine sensitizes pituitary adenomas cells to temozolomide through cathepsin B–dependent and caspase-dependent apoptotic pathways

      Congxin Dai, Bo Zhang, Xiaohai Liu, Kai Guo, Sihai Ma, Feng Cai, Yakun Yang, Yong Yao, Ming Feng, Xinjie Bao, Kan Deng, Yonghui Jiao, Zhenqing Wei, Wei Junji, Bing Xing, Wei Lian and Renzhi Wang

      Accepted manuscript online: 6 APR 2013 02:13AM EST | DOI: 10.1002/ijc.28199

  64. Epidemiology

    1. Changes in treatment patterns and their influence on long-term survival in patients with stage I-III gastric cancer in the Netherlands

      A.E. Dassen, J.L. Dikken, C.J.H. van de Velde, M.W.J.M. Wouters, K. Bosscha and V.E.P.P. Lemmens

      Accepted manuscript online: 6 APR 2013 02:11AM EST | DOI: 10.1002/ijc.28192

  65. Mini Reviews

    1. Epigenetic regulation of hypoxia-responsive gene expression: Focusing on chromatin and DNA modifications

      Ya-Ping Tsai and Kou-Juey Wu

      Accepted manuscript online: 6 APR 2013 02:11AM EST | DOI: 10.1002/ijc.28190

  66. Cancer Cell Biology

    1. Platelet-type 12- lipoxygenase induces MMP9 expression and cellular invasion via activation of PI3K/AKT/NF-κB

      Ashok-kumar Dilly, Prasanna Ekambaram, Yande Guo, Yinlong Cai, Stephanie C. Tucker, Rafael Fridman, Mustapha Kandouz and Kenneth V. Honn

      Accepted manuscript online: 23 MAR 2013 03:40AM EST | DOI: 10.1002/ijc.28165

  67. Cancer Therapy

    1. Promising biomarkers for predicting the outcomes of patients with KRAS wild-type metastatic colorectal cancer treated with anti-epidermal growth factor receptor monoclonal antibodies: A systematic review with meta-analysis

      Zu-Yao Yang, Xin-Yin Wu, Ya-Fang Huang, Meng-Yang Di, Da-Yong Zheng, Jin-Zhang Chen, Hong Ding, Chen Mao and Jin-Ling Tang

      Accepted manuscript online: 11 MAR 2013 01:08PM EST | DOI: 10.1002/ijc.28153

  68. Cancer Cell Biology

    1. MicroRNA-146a targets PRKCE to modulate papillary thyroid tumor development

      Xiaoping Zhang, Dan Li, Maoquan Li, Meng Ye, Lanbao Ding, Haidong Cai, Da Fu and Zhongwei Lv

      Accepted manuscript online: 2 MAR 2013 04:49AM EST | DOI: 10.1002/ijc.28141

    2. AMXT-1501, a novel polyamine transport inhibitor, synergizes with DFMO in inhibiting neuroblastoma cell proliferation by targeting both ornithine decarboxylase and polyamine transport

      Katherine Samal, Ping Zhao, Ann Kendzicky, Lisette P. Yco, Heather McClung, Eugene Gerner, Mark Burns, André S. Bachmann and Giselle Sholler

      Accepted manuscript online: 2 MAR 2013 04:49AM EST | DOI: 10.1002/ijc.28139

  69. Early Detection and Diagnosis

    1. A plasma microRNA panel for early detection of colorectal cancer

      Shuyang Wang, Jianbin Xiang, Zhaoyong Li, Shaohua Lu, Jie Hu, Xue Gao, Lei Yu, Lei Wang, Jiping Wang, Ying Wu, Zongyou Chen and Hongguang Zhu

      Accepted manuscript online: 2 MAR 2013 04:49AM EST | DOI: 10.1002/ijc.28136

  70. Epidemiology

    1. Analgesic use and the risk of kidney cancer: A meta-analysis of epidemiologic studies

      Toni K. Choueiri, Youjin Je and Eunyoung Cho

      Accepted manuscript online: 7 FEB 2013 07:05AM EST | DOI: 10.1002/ijc.28093

  71. Cancer Cell Biology

    1. Cell type specific interleukin-6 induced responses in tumor keratinocytes and stromal fibroblasts are essential for invasive growth

      Sofia Depner, Wiltrud Lederle, Claudia Gutschalk, Nina Linde, Alexandra Zajonz and Margareta M. Mueller

      Accepted manuscript online: 20 NOV 2012 07:24AM EST | DOI: 10.1002/ijc.27951

  72. Tumor Immunology

    1. Human monoclonal antibody GNX-8 directed to extended type 1 chain: Specific binding to human colorectal cancer

      Mei-Chun Yang, Feng-Lin Hsu, Kazuko Handa, Senitiroh Hakomori, Mei-Hsien Lee, Liahng-Yirn Liu, Shu-Yen Chang, Jerry Ting, Jaw-Yuan Wen, Isao Ishida and Tong-Hsuan Chang

      Article first published online: 21 DEC 2009 | DOI: 10.1002/ijc.25131

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