International Journal of Cancer

Cover image for Vol. 139 Issue 11

Editor-in-Chief: Professor Peter Lichter, DKFZ, Germany

Impact Factor: 5.531

ISI Journal Citation Reports © Ranking: 2015: 29/213 (Oncology)

Online ISSN: 1097-0215

Editors' Choice

2016 (Volume 139)

December (Issue 11)

Cell autonomous or systemic EGFR blockade alters the immune-environment in squamous cell carcinomas
Francesca Mascia, Derek T. Schloemann, Christophe Cataisson, Katherine M. McKinnon, Ludmila Krymskaya, Karen M. Wolcott and Stuart H. Yuspa

November (Issue 10)

A prospective study of dietary patterns and cancer mortality among Blacks and Whites in the REGARDS cohort
Tomi Akinyemiju, Justin Xavier Moore, Maria Pisu, Susan G. Lakoski, James Shikany, Michael Goodman and Suzanne E. Judd

November (Issue 9)

OTX015 (MK-8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models
Caroline Berenguer-Daiz, Lucile Astorgues-Xerri, Elodie Odore, Mylène Cayol, Esteban Cvitkovic, Kay Noel, Mohamed Bekradda, Sarah MacKenzie, Keyvan Rezai, François Lokiec, Maria E. Riveiro and L’Houcine Ouafik

October (Issue 8)

Fibroblast recruitment as a tool for ovarian cancer detection and targeted therapy
Roni Oren, Yoseph Addadi, Lian Narunsky Haziza, Hagit Dafni, Ron Rotkopf, Gila Meir, Ami Fishman and Michal Neeman

October (Issue 7)

Combination of carmustine and selenite effectively inhibits tumor growth by targeting androgen receptor, androgen receptor-variants, and Akt in preclinical models: New hope for patients with castration resistant prostate cancer
Vijayalakshmi Thamilselvan, Mani Menon and Sivagnanam Thamilselvan

September (Issue 6)

Tyrosine kinase inhibitor sunitinib therapy is effective in the treatment of bone metastasis from cancer of unknown primary: Identification of clinical and immunohistochemical biomarkers predicting survival
Yifei Ma, Wang Zhou, Shaohui He, Wei Xu and Jianru Xiao

September (Issue 5)

Stillbirth and neonatal death among female cancer survivors: A national cohort study
Jianguang Ji, Jan Sundquist and Kristina Sundquist

August (Issue 4)

A novel approach for targeted elimination of CSPG4-positive triple-negative breast cancer cells using a MAP tau-based fusion protein
Manal Amoury, Radoslav Mladenov, Thomas Nachreiner, Anh-Tuan Pham, Dmitrij Hristodorov, Stefano Di Fiore, Wijnand Helfrich, Alessa Pardo, Georg Fey, Michael Schwenkert, Theophilus Thepen, Fabian Kiessling, Ahmad F. Hussain, Rainer Fischer, Katharina Kolberg and Stefan Barth

August (Issue 3)

Predictive imaging of chemotherapeutic response in a transgenic mouse model of pancreatic cancer
Ping Wang, Byunghee Yoo, Sarah Sherman, Pinku Mukherjee, Alana Ross, Pamela Pantazopoulos, Victoria Petkova, Christian Farrar, Zdravka Medarova and Anna Moore

July (Issue 2)

Functional imaging of the angiogenic switch in a transgenic mouse model of human breast cancer by dynamic contrast enhanced magnetic resonance imaging
Lorena Consolino, Dario Livio Longo, Walter Dastrù, Juan Carlos Cutrin, Daniela Dettori, Stefania Lanzardo, Salvatore Oliviero, Federica Cavallo and Silvio Aime

July (Issue 1)

Long term, continuous exposure to panobinostat induces terminal differentiation and long term survival in the TH-MYCN neuroblastoma mouse model
Kelly Waldeck, Carleen Cullinane, Kerry Ardley, Jake Shortt, Ben Martin, Richard W. Tothill, Jason Li, Ricky W. Johnstone, Grant A. McArthur, Rodney J. Hicks and Paul J. Wood

2016 (Volume 138)

June (Issue 12)

Sunitinib activates Axl signaling in renal cell cancer
Johannes C. van der Mijn, Henk J. Broxterman, Jaco C. Knol, Sander R. Piersma, Richard R. De Haas, Henk Dekker, Thang V. Pham, Victor W. Van Beusechem, Balazs Halmos, James W. Mier, Connie R. Jiménez and Henk M.W. Verheul

June (Issue 11)

Cathepsin L inactivation leads to multimodal inhibition of prostate cancer cell dissemination in a preclinical bone metastasis model
Dhivya R. Sudhan, Christine Pampo, Lori Rice and Dietmar W. Siemann

May (Issue 10)

HDAC5 controls the functions of Foxp3+ T-regulatory and CD8+ T cells
Haiyan Xiao, Jing Jiao, Liqing Wang, Shaun O'Brien, Kheng Newick, Liang-Chuan S. Wang, Eva Falkensammer, Yujie Liu, Rongxiang Han, Veena Kapoor, Finn K. Hansen, Thomas Kurz, Wayne W. Hancock and Ulf H. Beier

May (Issue 9)

Endogenous conversion of ω-6 to ω-3 polyunsaturated fatty acids in fat-1 mice attenuated intestinal polyposis by either inhibiting COX-2/β-catenin signaling or activating 15-PGDH/IL-18
Young-Min Han, Jong-Min Park, Ji-Young Cha, Migyeong Jeong, Eun-Jin Go and Ki Baik Hahm

April (Issue 8)

Contribution of rare germline copy number variations and common susceptibility loci in Lynch syndrome patients negative for mutations in the mismatch repair genes
Rolando A.R. Villacis, Priscila M. Miranda, Israel Gomy, Erika M.M. Santos, Dirce M. Carraro, Maria I. Achatz, Benedito M. Rossi and Silvia R. Rogatto

April (Issue 7)

Perioperative treatment with the new synthetic TLR-4 agonist GLA-SE reduces cancer metastasis without adverse effects
Pini Matzner, Liat Sorski, Lee Shaashua, Ely Elbaz, Hagar Lavon, Rivka Melamed, Ella Rosenne, Neta Gotlieb, Amit Benbenishty, Steve G. Reed and Shamgar Ben-Eliyahu

March (Issue 6)

Combination therapy with zoledronic acid and cetuximab effectively suppresses growth of colorectal cancer cells regardless of KRAS status
Junko Kato, Manabu Futamura, Masako Kanematsu, Siqin Gaowa, Ryutaro Mori, Toshiyuki Tanahashi, Nobuhisa Matsuhashi and Kazuhiro Yoshida

March (Issue 5)

Patient-individualized CD8+ cytolytic T-cell therapy effectively combats minimal residual leukemia in immunodeficient mice
Eva Distler, Jana Albrecht, Ariane Brunk, Shamsul Khan, Elke Schnürer, Michaela Frey, Anja Mottok, Ana-Laura Jordán-Garrote, Christian Brede, Andreas Beilhack, Andreas Mades, Dirk Tomsitz, Matthias Theobald, Wolfgang Herr and Udo F. Hartwig

February (Issue 4)

A potent immunotoxin targeting fibroblast activation protein for treatment of breast cancer in mice
Jinxu Fang, Liang Xiao, Kye-Il Joo, Yarong Liu, Chupei Zhang, Shuanglong Liu, Peter S. Conti, Zibo Li and Pin Wang

February (Issue 3)

Brief-exposure to preoperative bevacizumab reveals a TGF-β signature predictive of response in HER2-negative breast cancers
Vinay Varadan, Sitharthan Kamalakaran, Hannah Gilmore, Nilanjana Banerjee, Angel Janevski, Kristy L.S. Miskimen, Nicole Williams, Ajay Basavanhalli, Anant Madabhushi, Kimberly Lezon-Geyda, Veerle Bossuyt, Donald R. Lannin, Maysa Abu-Khalaf, William Sikov, Nevenka Dimitrova and Lyndsay N. Harris

January (Issue 2)

Mesenchymal stem cells regulate melanoma cancer cells extravasation to bone and liver at their perivascular niche
Diego Correa, Rodrigo A. Somoza, Paul Lin, William P. Schiemann and Arnold I. Caplan

January (Issue 1)

Inhibition of class I histone deacetylases by romidepsin potently induces Epstein-Barr virus lytic cycle and mediates enhanced cell death with ganciclovir
Kwai Fung Hui et al (pages 125–136)

2015 (Volume 137)

December (Issue 12)

Immuno-based detection of extracellular vesicles in urine as diagnostic marker for prostate cancer
Diederick Duijvesz et al (pages 2869–2878)

December (Issue 11)

The Fc-alpha receptor is a new target antigen for immunotherapy of myeloid leukemia
Radoslav Mladenov et al (pages 2729-2738)

November (Issue 10)

Selective depletion of tumor neovasculature by microbubble destruction with appropriate ultrasound pressure
Junfen Wang et al. (pages 2478-2491)

November (Issue 9)

Potent and long-term antiangiogenic efficacy mediated by FP3-expressing oncolytic adenovirus
Il-Kyu Cho et al. (Pages 2253–2269)

October (Issue 8)

ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors
Ping Zhang et al. (Pages 2007–2018)

October (Issue 7)

Treatment of melanoma with a serotype 5/3 chimeric oncolytic adenovirus coding for GM-CSF: Results in vitro, in rodents and in humans
S. Bramante et al. (Pages 1775–1783)

October (Issue 6)

A natural HIV p17 protein variant up-regulates the LMP-1 EBV oncoprotein and promotes the growth of EBV-infected B-lymphocytes: Implications for EBV-driven lymphomagenesis in the HIV setting
D. Martorelli et al. (Pages 1374–1385)

September (Issue 5)

NKT cells act through third party bone marrow-derived cells to suppress NK cell activity in the liver and exacerbate hepatic melanoma metastases
L. Sadegh et al. (Pages 1085 – 1094)

August (Issue 4)

Engineered adenoviruses combine enhanced oncolysis with improved virus production by mesenchymal stromal carrier cells
K. Hammer et al. (Pages 978 – 990)

August (Issue 3)

The rarity of ALDH+ cells is the key to separation of normal versus leukemia stem cells by ALDH activity in AML patients
V. T. Hoang et al. (Pages 525 – 536)

July (Issue 2)

Permissive expansion and homing of adoptively transferred T cells in tumor-bearing hosts
C. Perez et al.(Pages 359 – 371)

July (Issue 1)

CD20 alternative splicing isoform generates immunogenic CD4 helper T epitopes
C. Vauchy et al.(Pages 116 – 126)

2015 (Volume 136)

June (Issue 12)

A comprehensively characterized large panel of head and neck cancer patient-derived xenografts identifies the mTOR inhibitor everolimus as potential new treatment option
K. Klinghammer et al. (Pages 2940 – 2948)

June (Issue 11)

Identification of NY-BR-1-specific CD4+ T cell epitopes using HLA-transgenic mice
A. Gardyan et al. (Pages 2588 – 2597)

May (Issue 10)

Chromosome instability in diffuse large B cell lymphomas is suppressed by activation of the noncanonical NF-κB pathway
S. Ramachandiran et al. (Pages 2341 – 2351)

May (Issue 9)

Circulating tumor DNA and circulating tumor cells in metastatic triple negative breast cancer patients
J. Madic et al. (Pages 2158 – 2165)

April (Issue 8)

Potent antitumor activity of cabozantinib, a c-MET and VEGFR2 inhibitor, in a colorectal cancer patient-derived tumor explant model
E-K. Song et al. (Pages 1967 – 1975)

April (Issue 7)

Metastasis blood test by flow cytometry: In vivo cancer spheroids and the role of hypoxia
V. Denes et al. (Pages 1528 – 1536)

March (Issue 6)

Assessment of ovarian cancer conditions from exhaled breath
H. Amal et al. (Pages E614 – E622)

March (Issue 5)

Identification of predictive factors of response to the BH3-mimetic molecule ABT-737: An ex vivo experiment in human serous ovarian carcinoma
S. Lheureux et al. (Pages E340 – E350)

February (Issue 4)

Oncolytic adenovirus and doxorubicin-based chemotherapy results in synergistic antitumor activity against soft-tissue sarcoma
M. Siurala et al. (Pages 945 – 954)

February (Issue 3)

Interruption of KLF5 acetylation converts its function from tumor suppressor to tumor promoter in prostate cancer cells
X. Li et al. (Pages 536 – 546)

January (Issue 2)

Histone lysine methyltransferase SUV39H1 is a potent target for epigenetic therapy of hepatocellular carcinoma
T. Chiba et al. (Pages 289 – 298)

January (Issue 1)

Development of thyroglobulin antibodies after GVAX immunotherapy is associated with prolonged survival
A. De Remigis et al.(Pages 127 – 137)

2014 (Volume 135)

December (Issue 12)

Development of a dendritic cell-targeting lipopeptide as an immunoadjuvant that inhibits tumor growth without inducing local inflammation
T. Akazawa et al.(Pages 2847 – 2856)

December (Issue 11)

Immunotherapy of B-cell non-Hodgkin lymphoma by targeting the chemokine receptor CXCR5 in a preclinical mouse model
H. Panjideh et al.(Pages 2623 – 2632)

November (Issue 10)

Risk factors for cancers of unknown primary site: Results from the prospective EPIC cohort
R. Kaaks et al.(Pages 2475 – 2481)

November (Issue 9)

Calcium-sensing receptor silencing in colorectal cancer is associated with promoter hypermethylation and loss of acetylation on histone 3
I. S. Fetahu et al.(Pages 2014 – 2023)

October (Issue 8)

Anti-VEGF antibody enhances the antitumor effect of CD40
S. Selvaraj et al.(Pages 1983 – 1988)

October (Issue 7)

Ha-ras and β-catenin oncoproteins orchestrate metabolic programs in mouse liver tumors
E. B. Unterberger et al.(Pages 1574 – 1585)

September (Issue 6)

Multilayer-omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome
E. Arai et al.(Pages 1330 – 1342)

September (Issue 5)

CD24 knockout prevents colorectal cancer in chemically induced colon carcinogenesis and in APCMin/CD24 double knockout transgenic mice
I. Naumov et al.(Pages 1048 – 1059)

August (Issue 4)

A newly synthesized compound, 4′-geranyloxyferulic acid–N(omega)-nitro-l-arginine methyl ester suppresses inflammation-associated colorectal carcinogenesis in male mice
M. Masahito et al.(Pages 774 – 784)

August (Issue 3)

Beneficial bacteria stimulate host immune cells to counteract dietary and genetic predisposition to mammary cancer in mice
J. R. Lakritz et al.(Pages 529 – 540)

July (Issue 2)

Predictability, efficacy and safety of radiosensitization of glioblastoma-initiating cells by the ATM inhibitor KU-60019
D. Vecchio et al.(Pages 479 – 491)

July (Issue 1)

Multilayered molecular profiling supported the monoclonal origin of metastatic renal cell carcinoma
Y. Huang et al.(Pages 78 – 87)

2014 (Volume 134)

The bispecific immunoligand ULBP2-aCEA redirects natural killer cells to tumor cells and reveals potent anti-tumor activity against colon carcinoma

Achim Rotheet al.
Vol. 134, No. 12 (June 2014): 2829–2840

Origin and pharmacological modulation of tumor-associated regulatory dendritic cells

Hua Zhong et al.
Vol. 134, No. 11 (June 2014): 2633–2645

Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants

Vanya D. Peltekova et al.
Vol. 134, No. 10 (May 2014): 2330–2341

Progression of carcinogen-induced fibrosarcomas is associated with the accumulation of naïve CD4 T cells via blood vessels and lymphatics
Beatrice Ondondo et al.
Vol. 134, No. 9 (May 2014): 2156–2167

Cancer-associated fibroblasts might sustain the stemness of scirrhous gastric cancer cells via transforming growth factor-β signaling
Tsuyoshi Hasegawa et al.
Vol. 134, No. 8 (April 2014): 1785–1795

Molecular characterization of cancer reveals interactions between ionizing radiation and chemicals on rat mammary carcinogenesi
Tatsuhiko Imaoka et al.
Vol. 134, No. 7 (April 2014): 1529–1538

Complete regression of glioblastoma by mesenchymal stem cells mediated prodrug gene therapy simulating clinical therapeutic scenario
Cestmir Altaner et al.
Vol. 134, No. 6 (March 2014): 1458–1465

The proinflammatory peptide substance P promotes blood–brain barrier breaching by breast cancer cells through changes in microvascular endothelial cell tight junction
Pedro L.Rodriguez et al.
Vol. 134, No. 5 (March 2014): 1034-1044

Presence of disseminated tumor cells in bone marrow correlates with tumor stage and nodal involvement in cervical cancer patients
Tanja Fehm et al.
Vol. 134, No. 4 (February 2014): 925-931

Tumor stroma and differentiated cancer cells can be originated directly from polyploid giant cancer cells induced by paclitaxel
Shiwu Zhang et al.
Vol. 134, No. 3 (February 2014): 508-518

The antibody-based targeted delivery of interleukin-4 and 12 to the tumor neovasculature eradicates tumors in three mouse models of cancer
Hemmerle Teresa and Neri Dario
Vol. 134, No. 2 (January 2014): 467-477

Expression differences between African American and Caucasian prostate cancer tissue reveals that stroma is the site of aggressive changes
Yu et al.
Vol. 134, No. 1 (January 2014): 81–91

2013 (Volume 133)

Deficiency of Kruppel-like factor KLF4 in mammary tumor cells inhibits tumor growth and pulmonary metastasis and is accompanied by compromised recruitment of myeloid-derived suppressor cells
Yu et al.
Vol. 133, No. 12 (December 2013): 2872–2883

Targeting breast cancer-initiating/stem cells with melanoma differentiation-associated gene-7/interleukin-24
Bhutia et al.
Vol. 133, No. 11 (December 2013): 2726–2736

The metastatic microenvironment: Lung-derived factors control the viability of neuroblastoma lung metastasis
Maman et al.
Vol. 133, No. 10 (November 2013): 2296–2306

Antitumor T cell responses in bladder cancer
Horn et al.
Vol. 133, No. 9 (November 2013): 2145–2156

IL-1b and leukemia stem cells
Yang et al.
Vol. 133, No. 8(October 2013): 1967–1981

Pediatric leukemia xenotransplantation model
Woiterski et al.
Vol. 133, No. 7 (October 2013): 1334-1344

Clinical tests for the impact of HPV vaccine
Meites et al.
Vol. 133, No. 5 (September 2013): 1101-1106

Dysfunctional endothelium stimulates metastasis
Franses et al.
Vol. 133, No. 6 (September 2013): 1334-1344

Microchimerism and breast cancer
Dhimolea et al.
Vol. 133, No. 4 (August 2013): 835-842

MiR-326 targeting of Smo in CML CD341 cells
Babashah et al.
Vol. 133, No. 3 (August 2013): 1547-1556

Establishment of tumor-specific copy number alterations from plasma DNA of patients with cancer
Heitzer et al.
Vol. 133, No. 2 (July 2013): 346-357

KRAS and BRAF mutation status in circulating colorectal tumor cells and their correlation with primary and metastatic tumor tissue
Mostert et al.
Vol. 133, No. 1 (July 2013): 130-141

2013 (Volume 132)

Roles of CCR4/CCL22 in Head and Neck Cancer Metastasis
Tsujikawa et al.
Vol. 132, No. 12 (15 June 2013): 2755–2766

Chemopreventive effect of AKBA on intestinal polyposis in APCMin/þ mice
Liu et al.
Vol. 132, No. 11 (1 June 2013): 2667–2681

Systemic reovirus therapy for liver metastases
Adair et al.
Vol. 132, No. 10 (15 May 2013): 2327–2338

GSI I induces apoptosis in CLL cells
Rosati et al.
Vol. 132, No. 8 (15 April 2013): 1940-1953

HDAC11 is a novel drug target in carcinomas
Deubzer et al.
Vol. 132, No. 8 (15 April 2013): 2200-2208

Gene profiling using next generation sequencing
Tran et al.
Vol. 132, No. 9 (1 May 2013): 1547–1555

Adenoviral HCC therapy in immunocompetent mice
Lin et al.
Vol. 132, No. 6 (15 March 2013): 1451–1462

Dynamics of T-Cell Infiltration
Fialova et al.
Vol. 132, No. 5 (1 March 2013): 1070-1079

MSC-directed imatinib therapy for colorectal cancer
Shinagawa et al.
Vol. 132, No. 4 (15 February 2013): 813–823

Novel driver mutations in colorectal cancer
Zhang et al.
Vol. 132, No. 3 (1 February 2013): 732-737

Plasma membrane proteomics in endometrial cancer
Yokoyama et al.
Vol. 132, No. 2 (15 January 2013): 472-484

VEGF-A and HIF-1a inhibition in sarcomas
Yeo-Jung et al.
Vol. 132, No. 1 (1 January 2013): 29-41

2012 (Volume 131)

Antibodies to the CEA N domain block metastasis
Aws Abdul-Wahid et al.
Vol. 131, No. 12 (15 December 2012): 2839-2851

Synthetic lethal targeting using APE1 inhibitors
Sultana et al.
Vol. 131, No. 11 (1 December 2012): 2433–2444

Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing’s sarcoma
Boro et al.
Vol. 131, No. 9 (1 November 2012): 2153-2164

Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48Cre/1 LSL-KrasG12D/1 mice
Altaf Mohammed, Li Qian, Naveena B. Janakiram et al.
Vol. 131, No. 8 (15 October 2012): 1951–1962

DNA methylation of the CYP1A1 enhancer is associated with smoking-induced genetic alterations in human lung
Xavier Tekpli, Shanbeh Zienolddiny, Vidar Skaug et al.
Vol. 131, No. 7 (1 October 2012): 1509–1516

Chemoprevention of familial adenomatous polyposis by bromo-noscapine (EM011) in the ApcMin/1 mouse model
Shiwang Li, Amr M. Ghaleb, Jing He et al.
Vol. 131, No. 6 (15 September 2012): 1435–1444

Pregnancy-induced chromatin remodeling in the breast of postmenopausal women
Jose Russo, Julia Santucci-Pereira, Ricardo Lopez de Cicco et al.
Vol. 131, No. 5 (1 September 2012): 1059–1070

Adoptive T cell therapy promotes the emergence of genomically altered tumor escape variants
Karen M. Kaluza, Jill M. Thompson, Timothy J. Kottke et al.
Vol. 131, No. 4 (15 August 2012): 844–854

Eradication of large tumors expressing human papillomavirus E7 protein by therapeutic vaccination with E7 fused to the extra domain a from fibronectin
Cristina Mansilla, Pedro Berraondo, Maika Durantez et al.
Vol. 131, No. 3 (1 August 2012): 641–651

The antitumor effect of a novel angiogenesis inhibitor (an octahydronaphthalene derivative) targeting both VEGF receptor and NF-κB pathway
Kosuke Watari, Mamiyo Nakamura, Yuichi Fukunaga et al.
Vol. 131, No. 2 (15 July 2012): 310-321

In vivo horizontal transmission of cancer and human genes
David M. Goldenberg, David Zagzag, Kerstin M. Heselmeyer-Haddad et al.
Vol. 131, No. 1 (1 July 2012): 49–58

2012 (Volume 130)

Carbidopa inhibits AR activity and tumor progression
Latif A. Wafa, Helen Cheng, Nathan Plaa et al.
Vol. 130, No. 12 (15 June 2012): 2835–2844

L1-CAM-targeted antibody therapy and 177Lu-radioimmunotherapy of disseminated ovarian cancer
Eliane Fischer, Jurgen Grunberg, Susan Cohrs et al.
Vol. 130, No. 11 (1 June 2012): 2715–2721

Diagnostic performance of one-step nucleic acid amplification for intraoperative sentinel node metastasis detection in breast cancer patients
Marie-Aude Le Frere-Belda, Anne-Sophie Bats, Florence Gillaizeau et al.
Vol. 130, No. 10 (15 May 2012): 2377–2386

Role of exosomes released by chronic myelogenous leukemia cells in angiogenesis
Simona Taverna, Anna Flugy, Laura Saieva et al.
Vol. 130, No. 9 (1 May 2012): 2033–2043

T cells raised against allogeneic HLA-A2/CD20 kill primary follicular lymphoma and acute lymphoblastic leukemia cells
Ingerid Weum Abrahamsen, Synneva Kjellevoll, Margrethe Greve-Isdahl et al.
Vol. 130, No. 8 (15 April 2012): 1821–1832

The WWP1 ubiquitin E3 ligase increases TRAIL resistance in breast cancer
Zhongmei Zhou, Rong Liu and Ceshi Chen
Vol. 130, No. 7 (1 April 2012): 1504–1510

Increased incidence of aflatoxin B1-induced liver tumors in hepatitis virus C transgenic mice
Emmanuelle Jeannot, Gary A. Boorman, Oksana Kosyk et al.
Vol. 130, No. 6 (15 March 2012): 1347–1356

Isolation of disseminated neuroblastoma cells from bone marrow aspirates for pretreatment risk assessment by array comparative genomic hybridization
Mado Vandewoestyne, Candy Kumps, Katrien Swerts et al.
Vol. 130, No. 5 (1 March 2012): 1098–1108

An intact retinoblastoma protein-binding site in Merkel cell polyomavirus large T antigen is required for promoting growth of Merkel cell carcinoma cells
Roland Houben, Christian Adam, Anne Baeurle et al.
Vol. 130, No. 4 (15 February 2012): 847–856

The novel lupus antigen related protein acheron enhances the development of human breast cancer
Rong Shao, Steve J. Scully, Jr., Wei Yan et al.
Vol. 130, No. 3 (1 February 2012): 544–554

A reduction of recipient regulatory T cells by cyclophosphamide contributes to an anti-tumor effect of nonmyeloablative allogeneic stem cell transplantation in mice
Ario Takeuchi, Masatoshi Eto, Hisakata Yamada et al.
Vol. 130, No. 2 (15 January 2012): 365–376

Serum antiglycan antibody detection of nonmucinous ovarian cancers by using a printed glycan array
Francis Jacob, Darlene R. Goldstein, Nicolai V. Bovin et al.
Vol. 130, No. 1 (1 January 2012): 138–146

2011 (Volume 129)

Effects of small molecule inhibitors of PI3K/Akt/mTOR signaling on neuroblastoma growth in vitro and in vivo
Lova Segerström, Ninib Baryawno, Baldur Sveinbjörnsson et al.
Vol. 129, No. 12 (15 December 2011): 2958–2965

Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity
Wenzhuo Zhuang, Bingzong Li, Linmei Long et al.
Vol. 129, No. 11 (1 December 2011): 2720–2731

Indirubin inhibits tumor growth by antitumor angiogenesis via blocking VEGFR2-mediated JAK/STAT3 signaling in endothelial cell
Xiaoli Zhang, Yajuan Song, Yuanyuan Wuet al.
Vol. 129, No. 10 (15 November 2011): 2502–2511

Humanized tumor mice—A new model to study and manipulate the immune response in advanced cancer therapy
Anja K. Wege, Wolfgang Ernst, Judith Eckl et al.
Vol. 129, No. 9 (1 November 2011): 2194–2206

A biparatopic anti-EGFR nanobody efficiently inhibits solid tumour growth
Rob C. Roovers, Maria J.W.D. Vosjan, Toon Laeremans et al.
Vol. 129, No. 8 (15 October 2011): 2013–2024

Identification of candidate predisposing copy number variants in familial and early-onset colorectal cancer patients
Ramprasath Venkatachalam, Eugene T.P. Verwiel, Eveline J. Kamping et al.
Vol. 129, No. 7 (1 October 2011): 1635–1642

Markers of fibrosis and epithelial to mesenchymal transition demonstrate field cancerization in histologically normal tissue adjacent to breast tumors
Kristina A. Trujillo, Christopher M. Heaphy, Minh Mai et al.
Vol. 129, No. 6 (15 September 2011): 1310–1321

Expression profiling of GIST: CD133 is associated with KIT exon 11 mutations, gastric location and poor prognosis
Gabriella Arne, Erik Kristiansson, Olle Nerman et al.
Vol. 129, No. 5 (1 September 2011): 1149–1161

Inhibition of neutrophil infiltration into A549 lung tumors in vitro and in vivo using a CXCR2-specific antagonist is associated with reduced tumor growth
Simon Tazzyman, Simon T. Barry, Susan Ashton et al.
Vol. 129, No. 4 (15 August 2011): 847–858

Human glioblastoma-initiating cells invade specifically the subventricular zones and olfactory bulbs of mice after striatal injection
Jerome Kroonen, Jessica Nassen, Yves-Gautier Boulanger et al.
Vol. 129, No. 3 (1 August 2011): 574–585

Tumor eradication by immunotherapy with biodegradable PLGA microspheres—an alternative to incomplete Freund’s adjuvant
Marc Mueller, Eva Schlosser, Bruno Gander et al.
Vol. 129, No. 2 (15 July 2011): 407–416

CXCR4 peptide antagonist inhibits primary breast tumor growth, metastasis and enhances the efficacy of anti-VEGF treatment or docetaxel in a transgenic mouse model
Saima Hassan, Marguerite Buchanan, Kaushar Jahan, et al.
Vol. 129, No. 1 (1 July 2011): 225–232

2011 (Volume 128)

A high omega-6 fat diet promotes pancreatic neoplasia
Eric C. Cheon, Matthew J. Strouch, Morgan R. Barron, et al.
Vol. 128, No. 12 (15 June 2011): 2783–2792

Axitinib in neuroblastoma xenografts
Jochen Rossler, Yann Monnet, Francoise Farace, et al.
Vol. 128, No. 11 (1 June 2011): 2748–2758

Medical radiation exposure and risk of retinoblastoma resulting from new germline RB1 mutation
Greta R. Bunin, Marc A. Felice, William Davidson, et al.
Vol. 128, No. 10 (15 May 2011): 2393–2404

E-cadherin expression on human carcinoma cell affects trastuzumab-mediated antibody-dependent cellular cytotoxicity through killer cell lectin-like receptor G1 on natural killer cells
Chisako Yamauchi, Satoshi Fujii, Taichi Kimura, et al.
Vol. 128, No. 9 (1 May 2011): 2125–2137

Micro-RNA-21 regulates TGF-b-induced myofibroblast differentiation by targeting PDCD4 in tumor-stroma interaction
Qin Yao, Siyu Cao, Chun Li, et al.
Vol. 128, No. 8 (15 Apr 2011): 1783–1792

Early life exposure to infections and risk of childhood acute lymphoblastic leukemia
Kevin Y. Urayama, Xiaomei Ma, Steve Selvin, et al.
Vol. 128, No. 7 (1 Apr 2011): 1632–1643

Dietary polyunsaturated fatty acids and breast cancer risk in Chinese women: a prospective cohort study
Harvey J. Murff, Xiao-Ou Shu, Honglan Li, et al.
Vol. 128, No. 6 (15 Mar 2011): 1434–1441

A tritherapy combination of a fusion protein vaccine with immune-modulating doses of sequential chemotherapies in an optimized regimen completely eradicates large tumors in mice
Xinxin Song, Wenzhong Guo, Jianfeng Cui, et al.
Vol. 128, No. 5 (1 Mar 2011): 1129–1138

Metastasis-focused cell-based SELEX generates aptamers inhibiting cell migration and invasion
Elina Zueva, Laila Illan Rubio, Frederic Duconge, et al.
Vol. 128, No. 4 (15 Feb 2011): 797–804

Tumor associated mesenchymal stem cells protects ovarian cancer cells from hyperthermia through CXCL12
Raphael Lis, Cyril Touboul, Pejman Mirshahi, et al.
Vol. 128, No. 3 (1 Feb 2011): 715–725

Increased expression and serum levels of the stromal cell-secreted protein periostin in breast cancer bone metastases
Sylvain Contie, Nathalie Voorzanger-Rousselot, Judith Litvin, et al.
Vol. 128, No. 2 (15 Jan 2011): 352–360

Synthetic siRNA targeting the breakpoint of EWS/Fli-1 inhibits growth of Ewing sarcoma xenografts in a mouse model
Iori Takigami, Takatoshi Ohno, Yukio Kitade, et al.
Vol. 128, No. 1 (1 Jan 2011): 216–226

2010 (Volume 127)

Vitamin K enhancement of sorafenib-mediated HCC cell growth inhibition in vitro and in vivo
Gang Wei, Meifang Wang, Terry Hyslop, et al.
Vol. 127, No. 12 (15 Dec 2010): 2949–2958

HB-EGF orchestrates the complex signals involved in triplenegative and trastuzumab-resistant breast cancer
Fusanori Yotsumoto, Eiji Oki, Eriko Tokunaga, et al.
Vol. 127, No. 11 (1 Dec 2010): 2707–2717

Glutamine targeting inhibits systemic metastasis in the VM-M3 murine tumor model
Laura M. Shelton, Leanne C. Huysentruyt & Thomas N. Seyfried
Vol. 127, No. 10 (15 Nov 2010): 2478–2485

The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: results of a prospective randomized phase II/III trial
Markus M. Heiss, Pawel Murawa, Piotr Koralewski, et al.
Vol. 127, No. 9 (1 Nov 2010): 2209-2221

The growth of brain tumors can be suppressed by multiple transplantation of mesenchymal stem cells expressing cytosine deaminase
Da-Young Chang, Seung-Wan Yoo, Youngtae Hong, et al.
Vol. 127, No. 8 (15 Oct 2010): 1975-1983

Tasmanian devil facial tumor disease: insights into reduced tumor surveillance from an unusual malignancy
Olga Kholmanskikh, Nicolas van Baren, Francis Brasseur, et al.
Vol. 127, No. 7 (1 Oct 2010): 1637-1642

Matrix metalloproteinase 11/stromelysin-3 exerts both activator and repressor functions during the hematogenous metastatic process in mice
David Brasse, Carole Mathelin, Khadija Leroux, et al.
Vol. 127, No. 6 (15 Sep 2010): 1347-1355

Parvovirus H1 selectively induces cytotoxic effects on human neuroblastoma cells
Jeannine Lacroix, Barbara Leuchs, Junwei Li, et al.
Vol. 127, No. 5 (1 Sep 2010): 1230-1239

The anticancer effect of probiotic Bacillus polyfermenticus on human colon cancer cells is mediated through ErbB2 and ErbB3 inhibition
Elise L. Ma, Yoon Jeong Choi, Jinyoung Choi, et al.
Vol. 127, No. 4 (15 Aug 2010): 780-790

Estrogen-induced angiogenic factors derived from stromal and cancer cells are differently regulated by enterolactone and genistein in human breast cancer in vivo
Niina M. Saarinen, Annelie Abrahamsson, Charlotta Dabrosin
Vol. 127, No. 3 (1 Aug 2010): 737-745

Autoantibody potential of cancer therapeutic monoclonal antibodies
John A. McIntyre, W. Page Faulk
Vol. 127, No. 2 (15 Jul 2010): 491-496

pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity
Angelo De Milito, Rossella Canese, Maria Lucia Marino, et al.
Vol. 127, No. 1 (1 Jul 2010): 207-219

2010 (Volume 126)

Fetal cell microchimerism in papillary thyroid cancer: studies in peripheral blood and tissues
Valentina Cirello, Michela Perrino, Carla Colombo, et al.
Vol. 126, No. 12 (15 Jun 2010): 2874-2878

The role of the intravascular microenvironment in spontaneous metastasis development
Qingbei Zhang, Meng Yang, Jikun Shen, et al.
Vol. 126, No. 11 (1 Jun 2010): 2534-2541

Ras inhibits endoplasmic reticulum stress in human cancer cells with amplified Myc
Shira Yaari-Stark, Maayan Shaked, Yael Nevo-Caspi, et al.
Vol. 126, No. 10 (15 May 2010): 2268-2281

Small molecule XIAP inhibitors sensitize childhood acute leukemia cells for CD95-induced apoptosis
Sandra Loeder, Annekathrin Drensek, Irmela Jeremias, et al.
Vol. 126, No. 9 (1 May 2010): 2216-2228

Loss of FBXW7, a cell cycle regulating gene, in colorectal cancer: Clinical significance
Masaaki Iwatsuki, Koshi Mimori, Hideshi Ishii, et al.
Vol. 126, No. 8 (15 Apr 2010): 1828-1837

Unifying roles for regulatory T cells and inflammation in cancer
Susan E. Erdman, Varada P. Rao, Werner Olipitz, et al.
Vol. 126, No. 7 (1 Apr 2010): 1651-1665

Loss of STARD10 expression identifies a group of poor prognosis breast cancers independent of HER2/Neu and triple negative status
Niamh C. Murphy, Andrew V. Biankin, Ewan K.A. Millar, et al.
Vol. 126, No. 6 (15 Mar 2010): 1445-1453

Primary gene-engineered neural stem/progenitor cells demonstrate tumor-selective migration and antitumor effects in glioma
Javier Mercapide, Germana Rappa, Fabio Anzanello, et al.
Vol. 126, No. 5 (1 Mar 2010): 1206-1215

Infiltrating CD11b CD11c cells have the potential to mediate inducible nitric oxide synthase-dependent cell death in mammary carcinomas of HER-2/neu transgenic mice
Nirmala Parajuli, Elisabeth Müller-Holzner, Günther Böck, et al.
Vol. 126, No. 4 (15 Feb 2010): 896-908

Adeno-associated virus-delivered short hairpin-structured RNA for androgen receptor gene silencing induces tumor eradication of prostate cancer xenografts in nude mice: A preclinical study
Aijing Sun, Jianxi Tang, Paul F. Terranova, et al.
Vol. 126, No. 3 (1 Feb 2010): 764-774

Sp1 coordinately regulates de novo lipogenesis and proliferation in cancer cells
Suying Lu, Michael C. Archer
Vol. 126, No. 2 (15 Jan 2010): 416-425

Triptolide functions as a potent angiogenesis inhibitor
Ming-Fang He, Yi-Hsien Huang, Li-Wha Wu, et al.
Vol. 126, No. 1 (1 Jan 2010): 266-278