Biopolymers

Cover image for Vol. 103 Issue 8

Edited By: Gary D. Glick

Impact Factor: 2.288

ISI Journal Citation Reports © Ranking: 2013: 45/74 (Biophysics); 190/291 (Biochemistry & Molecular Biology)

Online ISSN: 1097-0282

Associated Title(s): Peptide Science

Featured

  • In vitro selection of DNAs with an increased propensity to form small circles

    In vitro selection of DNAs with an increased propensity to form small circles

    Progress of cyclizability during in vitro selection. Time courses of cyclization of 460 pM DNA from libraries L0 through L6 using 100 U/ml T4 DNA ligase as detailed in the Methods. Aliquots were taken at 2, 4, 8, and 16 minutes for each reaction.

  • Isolation of dextran-hydrolyzing intestinal bacteria and characterization of their dextranolytic activities

    Isolation of dextran‐hydrolyzing intestinal bacteria and characterization of their dextranolytic activities

    RAPD-PCR products profiles of dextranolytic gut microbiota isolated from M17 (A), BHI (B), WCA (C), and MRS (D) media generated by the primers OPX14 and OPL5. M, 1kb Marker; X, B. xylanisolvens; T, B. thetaiotaomicron; O, B. ovatus; V, B. vulgatus.

  • Stacking geometry for non-canonical G:U wobble base pair containing dinucleotide sequences in RNA: dispersion-corrected DFT-D study

    Stacking geometry for non‐canonical G:U wobble base pair containing dinucleotide sequences in RNA: dispersion‐corrected DFT‐D study

    Intrinsic stacking energy contours for the dinucleotide sequences at 30o twist. Color bar is given in kcal/mol. The contour lines are 1 kcal/mol apart. (Crystal data points are in pink color and NMR data points have been marked by “+” in blue, whenever available. Black point represents the minimum energy conformation).

  • The role of proline-containing peptide triads in β-sheet formation: A kinetic study

    The role of proline‐containing peptide triads in β‐sheet formation: A kinetic study

    DUVRR spectra recorded on Day 45. (a–e) DUVRR spectra excited at 197 nm. Increase in the amide I peaks at 1680 cm−1 of 4,8PD and YE8 spectra indicate folded polypeptides.

  • Assessing protein conformational sampling and structural stability via de novo design and molecular dynamics simulations

    Assessing protein conformational sampling and structural stability via de novo design and molecular dynamics simulations

    Root mean square deviation (RMSD) as a function of energy for the native Top7 and its six helical-substituted chimeric proteins by 100 ns molecular dynamics simulations (A, C and D: GROMOS 54A7, AMBER 99sb, and CHARMM27, respectively) and (B) by 20,000 cycles of de novo design (module AbInitioRelax in Rosetta). The molecular dynamics simulation of native Top7 showed two main conformations due to a twist motion of one α-helix with respect to the other. Representative structures of each cluster are shown in cartoon model, along with a corresponding arrow to their RMSD cluster. The twist between the α-helices is highlighted by the positions of each helical axis, showed by orange lines. (α-helices are shown in blue, β-sheet in red and unstructured regions in white).

  • In vitro selection of DNAs with an increased propensity to form small circles
  • Isolation of dextran‐hydrolyzing intestinal bacteria and characterization of their dextranolytic activities
  • Stacking geometry for non‐canonical G:U wobble base pair containing dinucleotide sequences in RNA: dispersion‐corrected DFT‐D study
  • The role of proline‐containing peptide triads in β‐sheet formation: A kinetic study
  • Assessing protein conformational sampling and structural stability via de novo design and molecular dynamics simulations

Recently Published Issues

See all

Anniversary Special Issues

October 2013
Volume 99, Issue 10
Special Issue: Glycosciences

November 2013
Volume 99, Issue 11
Special Issue: Proteins

December 2013
Volume 99, Issue 12
Special Issue: Nucleic Acids

Going Green

BIOPOLYMERS PeptideBiopolymers became an Online Only journal in January, 2013. As you no longer receive Biopolymers in your mailbox, it's now more important than ever to sign up for email table-of-contents alerts. Be the first to know when Biopolymers publishes new research.

News

MG Prize winner

Announcing the 2015 Winner of the Biopolymers Murray Goodman Memorial Prize

Joan A Steitz PhD
Sterling Professor of Molecular Biophysics and Biochemistry
Investigator, Howard Hughes Medical Institute
Yale University

The prize recognizes Dr. Steitz's seminal contributions in the area of RNA structure and function.

SEARCH

SEARCH BY CITATION