Biotechnology and Bioengineering

Cover image for Vol. 113 Issue 10

Edited By: Douglas S. Clark

Impact Factor: 4.243

ISI Journal Citation Reports © Ranking: 2015: 24/161 (Biotechnology & Applied Microbiology)

Online ISSN: 1097-0290

Most Accessed 2009


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Top 25 Most Downloaded Articles

From September-December 2009


Microalgae for oil: Strain selection, induction of lipid synthesis and outdoor mass cultivation in a low-cost photobioreactor
Liliana Rodolfi, Graziella Chini Zittelli, Niccolò Bassi , Giulia Padovani , Natascia Biondi , Gimena Bonini , Mario R. Tredici
Volume 102, Issue 1, 2009

Opportunities for renewable bioenergy using microorganisms
Bruce E. Rittmann
Volume 100, Issue 2, 2008

A review of the current state of biodiesel production using enzymatic transesterification
Lene Fjerbaek, Knud V. Christensen, Birgir Norddahl
Volume 102, Issue 5, 2009

Fermentative butanol production by clostridia
Sang Yup Lee, Jin Hwan Park, Seh Hee Jang , Lars K. Nielsen, Jaehyun Kim, Kwang S. Jung
Volume 101, Issue 2, 2008

Cell-free production of transducible transcription factors for nuclear reprogramming
William C. Yang, Kedar G. Patel, Jieun Lee, Yohannes T. Ghebremariam, H. Edward Wong, John P. Cooke, James R. Swartz
Volume 104, Issue 6, 2009

A predictive high-throughput scale-down model of monoclonal antibody production in CHO cells
Rachel Legmann , H. Brett Schreyer, Rodney G. Combs, Ellen L. McCormick, A. Peter Russo, Seth T. Rodgers
Volume 104, Issue 6, 2009

Hydrogels as extracellular matrix mimics for 3D cell culture
Mark W. Tibbitt, Kristi S. Anseth
Volume 103, Issue 4, 2009

Energy from algae using microbial fuel cells
Sharon B. Velasquez-Orta, Tom P. Curtis, Bruce E. Logan
Volume 103, Issue 6, 2009

Metabolic engineering of Escherichia coli for the production of polylactic acid and its copolymers
Yu Kyung Jung, Tae Yong Kim, Si Jae Park, Sang Yup Lee
Volume 105, Issue 1, 2010

A study of monoclonal antibody-producing CHO cell lines: What makes a stable high producer?
Janet Chusainow, Yuan Sheng Yang, Jessna H.M. Yeo, Poh Choo Toh, Parisa Asvadi, Niki S.C. Wong, Miranda G.S. Yap
Volume 102, Issue 4, 2009

Biosynthesis of polylactic acid and its copolymers using evolved propionate CoA transferase and PHA synthase
Taek Ho Yang, Tae Wan Kim, Hye Ok Kang, Sang-Hyun Lee, Eun Jeong Lee, Sung-Chul Lim, Sun Ok Oh, Ae-Jin Song, Si Jae Park , Sang Yup Lee
Volume 105, Issue 1, 2010

Large-scale biodiesel production from microalga Chlorella protothecoides through heterotrophic cultivation in bioreactors
Xiufeng Li, Han Xu, Qingyu Wu
Volume 98, Issue 4, 2007

Toward an aggregated understanding of enzymatic hydrolysis of cellulose: Noncomplexed cellulase systems
Yi-Heng Percival Zhang, Lee R. Lynd
Volume 88, Issue 7, 2004

Medical biofilms
James D. Bryers
Volume 100, Issue 1, 2008

Visualization of biomass solubilization and cellulose regeneration during ionic liquid pretreatment of switchgrass
Seema Singh, Blake A. Simmons, Kenneth P. Vogel
Volume 104, Issue 1, 2009

Metabolic engineering of Escherichia coli for the production of putrescine: A four carbon diamine
Zhi-Gang Qian, Xiao-Xia Xia, Sang Yup Lee
Volume 104, Issue 4, 2009

Fungal pretreatment of lignocellulose by Phanerochaete chrysosporium to produce ethanol from rice straw
Jin Seop Bak, Ja Kyong Ko, In-Geol Choi, Yong-Cheol Park, Jin-Ho Seo, Kyoung Heon Kim
Volume 104, Issue 3, 2009

Stem cell-based composite tissue constructs for regenerative medicine
Mohamed N. Rahaman, Jeremy J. Mao
Volume 91, Issue 3, 2005

Scale-up analysis for a CHO cell culture process in large-scale bioreactors
Zizhuo Xing, Brian M. Kenty, Zheng Jian Li, Steven S. Lee
Volume 103, Issue 4, 2009

Industrial systems biology
José Manuel Otero, Jens Nielsen
Volume 105, Issue 3, 2010



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Top 25 Most Downloaded Articles

From May - August 2009


Impact of tumor-specific targeting and dosing schedule on tumor growth inhibition after intravenous administration of siRNA-containing nanoparticles
Derek W. Bartlett, Mark E. Davis
Volume 99, Issue 4, 2008

Microalgae for oil: Strain selection, induction of lipid synthesis and outdoor mass cultivation in a low-cost photobioreactor
Liliana Rodolfi, Graziella Chini Zittelli, Niccolò Bassi , Giulia Padovani , Natascia Biondi , Gimena Bonini , Mario R. Tredici
Volume 102, Issue 1, 2009

Scale-up analysis for a CHO cell culture process in large-scale bioreactors
Zizhuo Xing, Brian M. Kenty, Zheng Jian Li, Steven S. Lee
Volume 103, Issue 4, 2009

Hydrogels as extracellular matrix mimics for 3D cell culture
Mark W. Tibbitt, Kristi S. Anseth
Volume 103, Issue 4, 2009

High-level protein expression in scalable CHO transient transfection
Jianxin Ye, Vanessa Kober, Melanie Tellers, Zubia Naji, Peter Salmon, Julia F. Markusen
Volume 103, Issue 3, 2009

A review of the current state of biodiesel production using enzymatic transesterification
Lene Fjerbaek, Knud V. Christensen, Birgir Norddahl
Volume 102, Issue 5, 2009

Opportunities for renewable bioenergy using microorganisms
Bruce E. Rittmann
Volume 100, Issue 2, 2008

Energy from algae using microbial fuel cells
Sharon B. Velasquez-Orta, Tom P. Curtis, Bruce E. Logan
Volume 103, Issue 6, 2009

Identification of cell culture conditions to control N-glycosylation site-occupancy of recombinant glycoproteins expressed in CHO cells
Martin Gawlitzek, Michael Estacio, Tobias Fürch, Robert Kiss
Volume 103, Issue 6, 2009

Host cell proteins in biologics development: Identification, quantitation and risk assessment
Xing Wang, Alan K. Hunter, Ned M. Mozier
Volume 103, Issue 3, 2009

Fermentative butanol production by clostridia
Sang Yup Lee, Jin Hwan Park, Seh Hee Jang , Lars K. Nielsen, Jaehyun Kim, Kwang S. Jung
Volume 101, Issue 2, 2008

Ionic liquid-mediated selective extraction of lignin from wood leading to enhanced enzymatic cellulose hydrolysis
Sang Hyun Lee, Thomas V. Doherty, Robert J. Linhardt, Jonathan S. Dordick
Volume 102, Issue 5, 2009

Directed evolution of a secretory leader for the improved expression of heterologous proteins and full-length antibodies in Saccharomyces cerevisiae
J. Andy Rakestraw, Stephen L. Sazinsky, Andrea Piatesi, Eugene Antipov, K. Dane Wittrup
Volume 103, Issue 6, 2009

Visualization of biomass solubilization and cellulose regeneration during ionic liquid pretreatment of switchgrass
Seema Singh, Blake A. Simmons, Kenneth P. Vogel
Volume 104, Issue 1, 2009

Large-scale biodiesel production from microalga Chlorella protothecoides through heterotrophic cultivation in bioreactors
Xiufeng Li, Han Xu, Qingyu Wu
Volume 98, Issue 4, 2007

A study of monoclonal antibody-producing CHO cell lines: What makes a stable high producer?
Janet Chusainow, Yuan Sheng Yang, Jessna H.M. Yeo, Poh Choo Toh, Parisa Asvadi, Niki S.C. Wong, Miranda G.S. Yap
Volume 102, Issue 4, 2009

Application of plant tissue cultures in phytoremediation research: Incentives and limitations
Pauline Doran
Volume 103, Issue 1, 2009

Comparative study of corn stover pretreated by dilute acid and cellulose solvent-based lignocellulose fractionation: Enzymatic hydrolysis, supramolecular structure, and substrate accessibility
Zhiguang Zhu, Noppadon Sathitsuksanoh, Todd Vinzant, Daniel J. Schell, James D. McMillan, Y.-H. Percival Zhang
Volume 103, Issue 4, 2009

Revival of the biological sunlight-to-biogas energy conversion system
Liesje De Schamphelaire, Willy Verstraete
Volume 103, Issue 2, 2009

Expression of anti-apoptosis genes alters lactate metabolism of Chinese Hamster Ovary cells in culture
Haimanti Dorai, Yun Seung Kyung, Dawn Ellis, CherylAnn Kinney, Chengbin Lin, David Jan, Gordon Moore, Michael J. Betenbaugh
Volume 103, Issue 3, 2009



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Top 25 Most Downloaded Articles

From January – April 2009


Microalgae for oil: Strain selection, induction of lipid synthesis and outdoor mass cultivation in a low-cost photobioreactor
Liliana Rodolfi, Graziella Chini Zittelli, Niccolò Bassi , Giulia Padovani , Natascia Biondi , Gimena Bonini , Mario R. Tredici
Volume 102, Issue 1, 2008

Opportunities for renewable bioenergy using microorganisms
Bruce E. Rittmann
Volume 100, Issue 2, 2008

A review of the current state of biodiesel production using enzymatic transesterification
Lene Fjerbaek, Knud V. Christensen, Birgir Norddahl
Volume 102, Issue 5, 2009

Fermentative butanol production by clostridia
Sang Yup Lee, Jin Hwan Park, Seh Hee Jang , Lars K. Nielsen, Jaehyun Kim, Kwang S. Jung
Volume 101, Issue 2, 2008

A study of monoclonal antibody-producing CHO cell lines: What makes a stable high producer?
Janet Chusainow, Yuan Sheng Yang, Jessna H.M. Yeo, Poh Choo Toh, Parisa Asvadi, Niki S.C. Wong, Miranda G.S. Yap
Volume 102, Issue 4, 2009

Ionic liquid-mediated selective extraction of lignin from wood leading to enhanced enzymatic cellulose hydrolysis
Sang Hyun Lee, Thomas V. Doherty, Robert J. Linhardt, Jonathan S. Dordick
Volume 102, Issue 5, 2009

Large-scale biodiesel production from microalga Chlorella protothecoides through heterotrophic cultivation in bioreactors
Xiufeng Li, Han Xu, Qingyu Wu
Volume 98, Issue 4, 2007

Toward an aggregated understanding of enzymatic hydrolysis of cellulose: Noncomplexed cellulase systems
Yi-Heng Percival Zhang, Lee R. Lynd
Volume 88, Issue 7, 2004

Understanding and harnessing the microaerobic metabolism of glycerol in Escherichia coli
Guyton Durnin, James Clomburg, Zeno Yeates, Pedro J.J. Alvarez, Kyriacos Zygourakis, Paul Campbell, Ramon Gonzalez
Volume 103, Issue 1, 2009

High-level protein expression in scalable CHO transient transfection
Jianxin Ye, Vanessa Kober, Melanie Tellers, Zubia Naji, Peter Salmon, Julia F. Markusen
Volume 103, Issue 3, 2009

An optimized microplate assay system for quantitative evaluation of plant cell wall-degrading enzyme activity of fungal culture extracts
Brian C. King, Marie K. Donnelly, Gary C. Bergstrom, Larry P. Walker, Donna M. Gibson
Volume 102, Issue 4, 2009

Generation of human embryonic stem cell-derived mesoderm and cardiac cells using size-specified aggregates in an oxygen-controlled bioreactor
Sylvia Niebruegge, Céline L. Bauwens, Raheem Peerani, Nimalan Thavandiran, Stephane Masse, Elias Sevaptisidis, Kumar Nanthakumar, Kim Woodhouse , Mansoor Husain, Eugenia Kumacheva, Peter W. Zandstra
Volume 102, Issue 2, 2009

Design of well and groove microchannel bioreactors for cell culture
Natanel Korin, Avishay Bransky, Maria Khoury, Uri Dinnar, Shulamit Levenberg
Volume 102, Issue 4, 2009

Medical biofilms
James D. Bryers
Volume 100, Issue 1, 2008

Scale-up analysis for a CHO cell culture process in large-scale bioreactors
Zizhuo Xing, Brian M. Kenty, Zheng Jian Li, Steven S. Lee
Volume 103, Issue 4, 2009

A clone screening method using mRNA levels to determine specific productivity and product quality for monoclonal antibodies
Christina J. Lee, Gargi Seth, Joni Tsukuda, Robert W. Hamilton
Volume 102, Issue 4, 2009

Stem cell-based composite tissue constructs for regenerative medicine
Mohamed N. Rahaman, Jeremy J. Mao
Volume 91, Issue 3, 2005

Effect of enzyme supplementation at moderate cellulase loadings on initial glucose and xylose release from corn stover solids pretreated by leading technologies
Rajeev Kumar, C.E. Wyman
Volume 102, Issue 2, 2009

Impact of tumor-specific targeting and dosing schedule on tumor growth inhibition after intravenous administration of siRNA-containing nanoparticles
Derek W. Bartlett, Mark E. Davis
Volume 99, Issue 4, 2007

Analysis of metabolic pathways and fluxes in a newly discovered thermophilic and ethanol-tolerant Geobacillus strain
Yinjie J. Tang, Rajat Sapra, Dominique Joyner, Terry C. Hazen, Samuel Myers, David Reichmuth, Harvey Blanch, Jay D. Keasling
Volume 102, Issue 5, 2009

Mechanism of cellulase reaction on pure cellulosic substrates
Rajesh Gupta, Y.Y. Lee
Volume 102, Issue 6, 2009

Revival of the biological sunlight-to-biogas energy conversion system
Liesje De Schamphelaire, Willy Verstraete
Volume 103, Issue 2, 2009

3D collagen cultures under well-defined dynamic strain: A novel strain device with a porous elastomeric support
Alice A. Tomei, Federica Boschetti, Francesca Gervaso, Melody A. Swartz
Volume 103, Issue 1, 2009

Application of plant tissue cultures in phytoremediation research: Incentives and limitations
Pauline Doran
Volume 103, Issue 1, 2009

Functional characterization of a bacterial expansin from Bacillus subtilis for enhanced enzymatic hydrolysis of cellulose
Eun Sil Kim, Hee Jin Lee, Won-Gi Bang, In-Geol Choi, Kyoung Heon Kim
Volume 102, Issue 5, 2009



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