Biotechnology and Bioengineering
Copyright © 2013 Wiley Periodicals, Inc., A Wiley Company

Edited By: Douglas S. Clark
Impact Factor: 3.946
ISI Journal Citation Reports © Ranking: 2011: 28/158 (Biotechnology & Applied Microbiology)
Online ISSN: 1097-0290
Most Accessed 2011
Top 25 Most Downloaded Articles
From September-December 2011
Ling Jiang, Jufang Wang, Shizhong Liang, Jin Cai, Zhinan Xu, Peilin Cen, Shangtian Yang, Shuang Li
Volume 108, Issue 1, 2011
L. A. Tribe, C. L. Briens, A. Margaritis
Volume 46, Issue 4, 1995
Mark D. Ungrin, Geoff Clarke, Ting Yin, Sylvia Niebrugge, M. Cristina Nostro, Farida Sarangi,Geoffrey Wood, Gordon Keller, PeterW. Zandstra
In Early View
Aggregates in monoclonal antibody manufacturing processes
María Vázquez-Rey, Dietmar A. Lang
Volume 108, Issue 7, 2011
A review of the mammalian unfolded protein response
Anirikh Chakrabarti, Aaron W. Chen, Jeffrey D. Varner
Comparison of α-amylase activities from different assay methods
Young J. Yoo, Juan Hong, Randolph T. Hatch
Volume 30, Issue 1, 1987
Liliana Rodolfi, Graziella Chini Zittelli, Niccolò Bassi, Giulia Padovani, Natascia Biondi, Gimena Bonini, Mario R. Tredici
Volume 102, Issue 1, 2009
Culture temperature modulates aggregation of recombinant antibody in cho cells
Natalia Gomez, Jayashree Subramanian, Jun Ouyang, Mary D.H. Nguyen, Matthew Hutchinson, Vikas K. Sharma, Andy A. Lin, Inn H. Yuk
Volume 109, Issue 1, 2012
Metabolic engineering of Escherichia coli for the production of polylactic acid and its copolymers
Yu Kyung Jung, Tae Yong Kim, Si Jae Park, Sang Yup Lee
Volume 105, Issue 1, 2010
Haimanti Dorai, Yun Seung Kyung, Dawn Ellis, CherylAnn Kinney, Chengbin Lin, David Jan, Gordon Moore, Michael J. Betenbaugh
Volume 103, Issue 3, 2009
Improving the efficiency of CHO cell line generation using glutamine synthetase gene knockout cells
Lianchun Fan, Ibrahim Kadura, Lara E. Krebs, Christopher C. Hatfield, Margaret M. Shaw, Christopher C. Frye
In Early View
Metabolic flux analysis of CHO cell metabolism in the late non-growth phase
Neelanjan Sengupta, Steven T. Rose, John A. Morgan
Volume 108, Issue 1, 2011
Joseph A. Rollin, Zhiguang Zhu, Noppadon Sathitsuksanoh, Y.-H. Percival Zhang
Volume 108, Issue 1, 2011
James F. Zawada, Gang Yin, Alexander R. Steiner, Junhao Yang, Alpana Naresh, Sushmita M. Roy, Daniel S. Gold, Henry G. Heinsohn, Christopher J. Murray
Volume 108, Issue 7, 2011
Synthesis and application of virus-based hybrid nanomaterials
Sang-Yup Lee, Jung-Sun Lim, Michael T. Harris
Volume 109, Issue 1, 2012
Hydrogels as extracellular matrix mimic for 3D cell culture
Mark W. Tibbitt, Kristi S. Anseth
Volume 103, Issue 4, 2009
Fermentative butanol production by clostridia
Sang Yup Lee, Jin Hwan Park, Seh Hee Jang, Lars K. Nielsen, Jaehyun Kim, Kwang S. Jung
Volume 101, Issue 2, 2008
Quantitative analysis of the fermentative metabolism of glycerol in Escherichia coli
Angela Cintolesi, James M. Clomburg, Venetia Rigou, Kyriacos Zygourakis, Ramon Gonzalez
Volume 109, Issue 1, 2012
Adriano Pinto Mariano, Nasib Qureshi, Rubens Maciel Filho, Thaddeus Chukwuemeka Ezeji
Volume 108, Issue 8, 2011
Mobile phase modifier effects in multimodal cation exchange chromatography
Melissa A. Holstein, Siddharth Parimal, Scott A. McCallum, Steven M. Cramer
Volume 109, Issue 1, 2012
Christopher A. Sellick, Alexandra S. Croxford, Arfa R. Maqsood, Gill Stephens, Hans V. Westerhoff, Royston Goodacre, Alan J. Dickson
Volume 108, Issue 12, 2011
Efren Pacis, Marcella Yu, Jennifer Autse, Robert Bayer, Feng Li
Volume 108, Issue 10, 2011
Laetitia Malphettes, Yevgeniy Freyvert, Jennifer Chang, Pei-Qi Liu, Edmond Chan, Jeffrey C. Miller, Zhe Zhou, Thu Nguyen, Christina Tsai, Andrew W. Snowden, Trevor N. Collingswood, Philip D. Gregory, Gregory J. Cost
Volume 106, Issue 5, 2010
Culture of microalgae Chlorella minutissima for biodiesel feedstock production
Haiying Tang, Meng Chen, M.E.D. Garcia, Nadia Abunasser, K.Y. Simon Ng, Steven O. Salley
Volume 108, Issue 10, 2011
Improved galactose fermentation of Saccharomyoces cerevisiae through inverse metabolic engineering
Ki-Sung Lee, Min-Eui Hong, Suk-Chae Jung, Suk-Jin Ha, Byung Jo Yu,Hyun Min Koo, Sung Min Park, Jin-Ho Seo, Dae-Hyuk Kweon, Jae Chan Park, Yong-Su Jin
Volume 108, Issue 3, 2011
Top 25 Most Downloaded Articles
From May-August 2011
A review of the mammalian unfolded protein response
Anirikh Chakrabarti, Aaron W. Chen, Jeffrey D. Varner
In Early View
James F. Zawada, Gang Yin, Alexander R. Steiner, Junhao Yang, Alpana Naresh, Sushmita M. Roy, Daniel S. Gold, Henry G. Heinsohn, Christopher J. Murray
Volume 108, Issue 7, 2011
Aggregates in monoclonal antibody manufacturing processes
María Vázquez-Rey, Dietmar A. Lang
Volume 108, Issue 7, 2011
Room temperature ionic liquids as emerging solvents for the pretreatment of lignocellulosic biomass
Mauricio Mora-Pale, Luciana Meli, Thomas V. Doherty, Robert J. Linhardt, Jonathan S. Dordick
Volume 108, Issue 6, 2011
Liliana Rodolfi, Graziella Chini Zittelli, Niccolò Bassi, Giulia Padovani, Natascia Biondi, Gimena Bonini, Mario R. Tredici
Volume 102, Issue 1, 2009
Fermentative butanol production by clostridia
Sang Yup Lee, Jin Hwan Park, Seh Hee Jang, Lars K. Nielsen, Jaehyun Kim, Kwang S. Jung
Volume 102, Issue 1, 2009
Minsoo Kim, Peter M. O'Callaghan, Kurt A. Droms, David C. James
Volume 108, Issue 10, 2011
Improved galactose fermentation of Saccharomyces cerevisiae through inverse metabolic engineering
Ki-Sung Lee, Min-Eui Hong, Suk-Chae Jung, Suk-Jin Ha, Byung Jo Yu, Hyun Min Koo, Sung Min Park, Jin-Ho Seo, Dae-Hyuk Kweon, Jae Chan Park, Yong-Su Jin
Volume 108, Issue 3, 2011
Efren Pacis, Marcella Yu, Jennifer Autsen, Robert Bayer, Feng Li
Volume 108, Issue 10, 2011
L. A. Tribe, C. L. Briens, A. Margaritis
Volume 46, Issue 4, 1995
Ionic liquid pretreatment of cellulosic biomass: Enzymatic hydrolysis and ionic liquid recycle
Kierston Shill, Sasisanker Padmanabhan, Qin Xin, John M. Prausnitz, Douglas S. Clark, Harvey W. Blanch
Volume 108, Issue 3, 2011
Synchronous fluorescence spectroscopy as a novel tool to enable PAT applications in bioprocesses
Ana P. Teixeira, Tiago M. Duarte, M.J.T. Carrondo, Paula M. Alves
Volume 108, Issue 8, 2011
Joseph A. Rollin, Zhiguang Zhu, Noppadon Sathitsuksanoh, Y.-H. Percival Zhang
Volume 108, Issue 1, 2011
Modeling the competition between aggregation and self-assembly during virus-like particle processing
Yong Ding, Yap Pang Chuan, Lizhong He, Anton P.J. Middelberg
Volume 107, Issue 3, 2010
Matthew Gagnon, Gregory Hiller, Yen-Tung Luan, Amy Kittredge, Jordy DeFelice, Denis Drapeau
Volume 108, Issue 6, 2011
Engineering butanol-tolerance in escherichia coli with artificial transcription factor libraries
Ju Young Lee, Kyung Seok Yang, Su A Jang, Bong Hyun Sung, Sun Chang Kim
Volume 108, Issue 4, 2011
Metabolic flux analysis of CHO cell metabolism in the late non-growth phase
Neelanjan Sengupta, Steven T. Rose, John A. Morgan
Volume 108, Issue 1, 2011
Three-dimensional cell culture microarray for high-throughput studies of stem cell fate
Tiago G. Fernandes, Seok-Joon Kwon, Shyam Sundhar Bale, Moo-Yeal Lee, Maria Margarida Diogo, Douglas S. Clark, Joaquim M.S. Cabral, Jonathan S. Dordick
Volume 106, Issue 1, 2010
Metabolic engineering of Escherichia coli for the production of polylactic acid and its copolymers
Yu Kyung Jung, Tae Yong Kim, Si Jae Park, Sang Yup Lee
Volume 105, Issue 1, 2010
Jeanette Bierwolf, Marc Lutgehetmann, Kai Feng, Johannes Erbes, Steffen Deichmann, Eva Toronyi, Christina Stieglitz, Bjoern Nashan, Peter X. Ma, Joerg M. Pollok
Volume 108, Issue 1, 2011
Christopher A. Sellick, Alexandra S. Croxford, Arfa R. Maqsood, Gill Stephens, Hans V. Westerhoff, Royston Goodacre, Alan J. Dickson
In Early View
Elizabeth J. Clarke, Christopher A. Voigt
Volume 108, Issue 3, 2011
Inhibition of starch synthesis results in overproduction of lipids in Chlamydomonas reinhardtii
Yantao Li, Danxiang Han, Guangrong Hu, Milton Sommerfeld, Qiang Hu
Volume 108, Issue 2, 2011
Christopher A. Sellick, Alexandra S. Croxford, Arfa R. Maqsood, Gill Stephens, Hans V. Westerhoff, Royston Goodacre, Alan J. Dickson
In Early View
Ionic liquid pretreatment of cellulosic biomass: Enzymatic hydrolysis and ionic liquid recycle
Kierston Shill, Sasisanker Padmanabhan, Qin Xin, John M. Prausnitz, Douglas S. Clark, Harvey W. Blanch
Volume 108, Issue 3, 2011
Top 25 Most Downloaded Articles
From January-April 2011
Microalgae for oil: Strain selection, induction of lipid synthesis and outdoor mass cultivation in a low-cost photobioreactor
Liliana Rodolfi, Graziella Chini Zittelli, Niccolò Bassi , Giulia Padovani , Natascia Biondi , Gimena Bonini , Mario R. Tredici
Volume 102, Issue 1, 2009
Industrial systems biology
José Manuel Otero, Jens Nielsen
Volume 105, Issue 3, 2010
Metabolic engineering of Escherichia coli for the production of polylactic acid and its copolymers
Yu Kyung Jung, Tae Yong Kim, Si Jae Park, Sang Yup Lee
Volume 105, Issue 1, 2010
Generation of a triple-gene knockout mammalian cell line using engineered zinc-finger nucleases
Pei-Qi Liu, Edmond M. Chan, Gregory J. Cost, Lin Zhang, Jianbin Wang, Jeffrey C. Miller, Dmitry Y. Guschin, Andreas Reik, Michael C. Holmes, John E. Mott, Trevor N. Collingwood, Philip D. Gregory
Volume 106, Issue 1, 2010
A review of the current state of biodiesel production using enzymatic transesterification
Lene Fjerbaek, Knud V. Christensen, Birgir Norddahl
Volume 102, Issue 5, 2009
A process for microbial hydrocarbon synthesis: Overproduction of fatty acids in Escherichia coli and catalytic conversion to alkanes
Rebecca M. Lennen, Drew J. Braden, Ryan M. West, James A. Dumesic, Brian F. Pfleger
Volume 106, Issue 2, 2010
Hydrogels as extracellular matrix mimics for 3D cell culture
Mark W. Tibbitt, Kristi S. Anseth
Volume 103, Issue 4, 2009
Large-scale biodiesel production from microalga Chlorella protothecoides through heterotrophic cultivation in bioreactors
Xiufeng Li, Han Xu, Qingyu Wu
Volume 98, Issue 4, 2007
Toward an aggregated understanding of enzymatic hydrolysis of cellulose: Noncomplexed cellulase systems
Yi-Heng Percival Zhang, Lee R. Lynd
Volume 88, Issue 7, 2004
Fermentative butanol production by clostridia
Sang Yup Lee, Jin Hwan Park, Seh Hee Jang , Lars K. Nielsen, Jaehyun Kim, Kwang S. Jung
Volume 101, Issue 2, 2008
A study of monoclonal antibody-producing CHO cell lines: What makes a stable high producer?
Janet Chusainow, Yuan Sheng Yang, Jessna H.M. Yeo, Poh Choo Toh, Parisa Asvadi, Niki S.C. Wong, Miranda G.S. Yap
Volume 102, Issue 4, 2009
Opportunities for renewable bioenergy using microorganisms
Bruce E. Rittmann
Volume 100, Issue 2, 2008
Biosynthesis of polylactic acid and its copolymers using evolved propionate CoA transferase and PHA synthase
Taek Ho Yang, Tae Wan Kim, Hye Ok Kang, Sang-Hyun Lee, Eun Jeong Lee, Sung-Chul Lim, Sun Ok Oh, Ae-Jin Song, Si Jae Park , Sang Yup Lee
Volume 105, Issue 1, 2010
Metabolite stress and tolerance in the production of biofuels and chemicals: Gene-expression-based systems analysis of butanol, butyrate, and acetate stresses in the anaerobe Clostridium acetobutylicum
Keith V. Alsaker, Carlos Paredes, Eleftherios T. Papoutsakis
Volume 105, Issue 6, 2010
Novel micro-bioreactor high throughput technology for cell culture process development: Reproducibility and scalability assessment of fed-batch CHO cultures
Ashraf Amanullah, Jose Manuel Otero, Mark Mikola, Amy Hsu, Jinyou Zhang, John Aunins, H. Brett Schreyer, James A. Hope, A. Peter Russo
Volume 106, Issue 1, 2010
Ionic liquid-mediated selective extraction of lignin from wood leading to enhanced enzymatic cellulose hydrolysis
Sang Hyun Lee, Thomas V. Doherty, Robert J. Linhardt, Jonathan S. Dordick
Volume 102, Issue 5, 2009
Host cell proteins in biologics development: Identification, quantitation and risk assessment
Xing Wang, Alan K. Hunter, Ned M. Mozier
Volume 103, issue 3, 2009
A mechanistic model of the enzymatic hydrolysis of cellulose
Seth E. Levine, Jerome M. Fox, Harvey W. Blanch, Douglas S. Clark
Volume 107, Issue 1, 2010
Inhibition of starch synthesis results in overproduction of lipids in Chlamydomonas reinhardtii
Yantao Li, Danxiang Han, Guangrong Hu, Milton Sommerfeld, Qiang Hu
Volume 107, Issue 2, 2010
High-level recombinant protein production in CHO cells using lentiviral vectors and the cumate gene-switch
Bruno Gaillet, Rénald Gilbert, Sophie Broussau, Amélie Pilotte, Félix Malenfant, Alaka Mullick, Alain Garnier and Bernard Massie
Volume 106, Issue 2, 2010
Continuous perfusion microfluidic cell culture array for high-throughput cell-based assays
Paul J. Hung, Philip J. Lee, Poorya Sabounchi, Robert Lin, Luke P. Lee
Volume 89, Issue 1, 2005
Identification and prevention of antibody disulfide bond reduction during cell culture manufacturing
Melody Trexler-Schmidt, Sandy Sargis, Jason Chiu, Stefanie Sze-Khoo, Melissa Mun, Yung-Hsiang Kao, Michael W. Laird
Volume 106, Issue 3, 2010
Scale-up analysis for a CHO cell culture process in large-scale bioreactors
Zizhuo Xing, Brian M. Kenty, Zheng Jian Li, Steven S. Lee
TCR-β repertoire analysis of antigen-specific single T cells using a high-density microcavity array
Atsushi Arakaki, Kaori Ooya, Yasuto Akiyama, Masahito Hosokawa, Masaru Komiyama, Akira Iizuka, Ken Yamaguchi, Tadashi Matsunaga
Volume 106, Issue 2, 2010

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