Journal of Neuroscience Research

Cover image for Vol. 92 Issue 11

Edited By: Jean de Vellis

Impact Factor: 2.729

ISI Journal Citation Reports © Ranking: 2013: 141/251 (Neurosciences)

Online ISSN: 1097-4547

Author Guidelines

NOTE TO NIH GRANTEES: Pursuant to the April 2008 NIH mandate, Wiley-Blackwell has been posting the accepted version of contributions authored by NIH grant-holders to PubMed Central upon acceptance with a 12-month embargo.

NIH Public Access Mandate. Journal of Neurological Research is fully compliant with the NIH Public Access Mandate. For more information please visit our policy statement at our NIH Author Services Page.

For additional tools visit Author Resources - an enhanced suite of online tools for Wiley Online Library journal authors, featuring Article Tracking, E-mail Publication Alerts and Customized Research Tools.

Author Guidelines

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The Journal of Neuroscience Research publishes novel research results that will advance our understanding of the development, functions and diseases of the nervous system,using molecular, cellular and systems approaches. JNR features full-length papers, mini-reviews, and commentaries. All new manuscripts should be submitted online and correspondence regarding editorial matters should be addressed to theEditor-in-Chief, Dr.Jean de Vellis.

Dr. Jean de Vellis
Intellectual and Developmental Disabilities Research Center
635 Charles E. Young Dr. South
Neuroscience Research Building, Ste. 3750
Los Angeles CA 90095-7332


Submission of Manuscripts

The journal to which you are submitting your manuscript employs a plagiarism detection system. By submitting your manuscript to this journal you accept that your manuscript may be screened for plagiarism against previously published works.

All manuscripts submitted to the Journal of Neuroscience Research must be submitted solely to this journal,may not have been published in any part or form in another publication of any type, professional or lay, and become the property of the publisher. No published material may be reproduced or published elsewhere without the written permission of the publisher and the author. The journal will not be responsible for the loss of manuscripts at any time. All statements in, or omissions from, published manuscripts are the responsibility of the authors who will assist the editors by reviewing proofs before publication. No page charges will be levied against an author or institution for publication in this journal.

If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.

For authors signing the copyright transfer agreement

If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:

CTA Terms and Conditions

For authors choosing OnlineOpen

If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):

Creative Commons Attribution License OAA

Creative Commons Attribution Non-Commercial License OAA

Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services and visit

If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit:

The goal of JNR is to provide a fair, rigorous and rapid review of all manuscripts. Color illustrations are encouraged for publication. The charge for color pages will be $500 each. In hardship cases, one free color page may be requested by contacting the Editor-in-Chief. Availability is limited. Authors for whom English is a second language may choose to have their manuscript professionally edited before submission to improve the English. A list of independent suppliers of editing services can be found at Japanese authors can also find a list of local English improvement services at All services are paid for and arranged by the author, and use of one of these services does not guarantee acceptance or preference for publication.

Focused, critical Mini-Reviews of a wide range of fore front areas of neuroscience will be considered for publication in JNR . The total length, including any figures and references, should not normally exceed 12 manuscript pages.

Associate Editors:

Dr. Rashmi Bansal
Department of Neuroscience
University of Connecticut Medical School, MC-3401
Farmington CT 06030-3401
Fax: 1 (860) 679-8140

Dr. Anne Baron Van Evercooren
Faculty de Med Salpetriere
105 Blvd de L Hopital
75634 Cedex, Paris, France
Fax: 31-01-4070-8117

Dr. Joyce Benjamins
Depatment of Neurology
3124 Elliman Building
Detroit, MI 48201-1908
Fax: 313-577-7552

Dr. Scott T. Brady
Department of Anatomy & Cell Biology
University of Illinois at Chicago
808 S. Wood St.
Rm CME 578(M/C 512)
Chicago, Illinois 60612
Fax: 1 (312)413-0354

Dr. Ellen Carpenter
Department of Psychiatry
UCLA School of Medicine
635 Charles E. Young Drive, South
NRB 303
Los Angeles, CA 90095
Fax: 310-206-5050

Dr. Monica Carson
Division of Biomedical Sciences
900 University Ave.
University of California, Riverside
Riverside, CA 92521-0121

Dr. Cristina Ghiani
Intellectual and Developmental Disability Research Center
Semel Institute for Neuroscience & Human Behavior, UCLA
Neuroscience Research Bldg, Room 260H
635 Charles E Young Dr South
Los Angeles, CA 90095

Dr. Kazuhiro Ikenaka
Okazaki National Research Institutes
National Institute of Physiological Science
38 Aza-nishigonaka
Okazaki, Aichi, Japan 444-8585
Fax: 81-564-59-5245

Dr. John A. Kessler
Ken and Ruth Davee Department of Neurology and Clinical Neurological Sciences
Abbott Hall, 11th Floor
Northwestern University Medical School
710 North Lake Shore Drive
Chicago, Illinois 60611-3078
Fax: 1 (312) 503-0872

Dr. Bertrand Lambolez
Neurobiologie des Processus Adaptatifs
Universite PM Curie
9 Quai St. Bernard
Paris, France 75005
Fax: 33-1-44-27-25-09

Dr. Michael S. Levine
Department of Psychiatry
760 Westwood Plaza
58-258E NPI
Los Angeles, California 90095
Fax: 1 (310) 206-5060

Dr. Wendy B. Macklin
Department of Cell & Developmental Biology
University of Colorado Denver Health Sciences Center
Aurora, Colorado 80045
Fax: 303-724-3420

Dr. Mary C. McKenna
Department of Pediatrics
University of Maryland School of Medicine
Room 10-031
655 W. Baltimore St.
Baltimore, Maryland 21201
Fax: 1 (410) 706-0020

Dr. Hideyuki Okano
Department of Physiology
Keio University School of Medicine
35 Shinanomachi, Shinjuku-ku
Tokyo 160-8582
Fax: 81 3-5363-3746

Dr. Jose Regino Perez-Polo
Department of Human Biological Chemistry and Genetics
University of Texas Medical Branch
301 University Boulevard
Galveston, TX 77555-0652
Fax: 1 (409) 772-8028

Dr. Yi Sun
Semel Institute for Neuroscience & Human Behavior, UCLA
UCLA School of Medicine
635 Charles E. Young Drive South
Los Angeles, CA 90095

Dr. James A Waschek
Department of Psychiatry
University of California, Los Angeles
Los Angeles, California

Yukio Yoneda
Laboratory of Molecular Pharmacology
Kanazawa University Graduate School
Kahuma-machi, Kanazawa
Ishikawa 920-1192, Japan


Focused, critical Mini-Reviews of a wide range of forefront areas of neuroscience will be considered for publication in the Journal of Neuroscience Research. The total length,including any figures, should not normally exceed 12 manuscript pages, using the standard format for regular articles.References should be carefully and critically chosen and kept to a logical minimum. Mini-reviews, whether author-initiated or solicited by the Journal, generally will be peer reviewed. Every attempt will be made to bring acceptable reviews to a rapid publication. Correspondence regarding submission of Mini-Reviews should be addressed to:

Dr. Rashmi Bansal
Department of Neuroscience
University of Connecticut Medical School, MC-3401
Farmington CT 06030-3401
Fax: 1 (860) 679-8140

Treatment of Experimental Animals

The Journal of Neuroscience Research endorses the view that the use of animals in research is an issue of legitimate concern, one that must follow carefully considered ethical standards. Specifically, it is required that animals used in research described in papers submitted to the Journal have been acquired and cared for in accordance with the guidelines published in the NIH Guide for the Care and Use of Laboratory Animals (National Institutes of Health Publication No. 85-23,revised 1985,available from: Office of Science and Health Reports,National Center for Research Resources, Westwood Building, Room 850, Bethesda, MD 20892; fax 301- 594-9111), and the principles presented in the "Guidelines for the Use of Animals in Neuroscience Research" by the Society for Neuroscience (available from the Society for Neuroscience, 11 Dupont Circle, N.W.,Washington, DC, 20036; tel 202-462-6688, fax 202-462- 2937; published in Membership Directory of the Society, pp. xxvii-xxviii,1992).

In addition, letters of submission accompanying manuscripts must contain a statement indicating that all animal protocols used have been approved by the authors' institutional animal experimentation committee, if applicable.

Manuscripts that do not comply with acceptable standards for the humane treatment of vertebrate animals will not be considered for publication.

Presentation of Text

Text should be presented in the following order: Abstract,Keywords, Introduction, Materials and Methods, Results, Discussion, Acknowledgments, References.

Organization of the Manuscript

Manuscripts must be submitted in English, and be type written, paginated, and double-spaced throughout. Material should be divided into logically organized sections with all headings and sub-headings clearly delineated. Full-length manuscripts in excess of 30 manuscript pages (including tables and figures) are discouraged. Papers not following the indicated format may be returned.

Text should be presented in the following order:

1) Title Page
2) Abstract
3) Key words
4) Introduction
5) Materials and Methods
6) Results
7) Discussion
8) Acknowledgments
9) References
10) Tables
11) Figure legends

Title Page

The title page should include the following:

1) Complete title
2) Names of all authors with affiliations*
3) Short running title (not to exceed 40 characters and spaces)
4) Corresponding author’s contact information including name, complete address, phone number, fax number and E-mail address.
5) Grant information

*Authorship should be discussed before an article is written. Contributors meeting the following criteria for authorship, as recommended by recommended by ICMJE, must be listed as authors of the manuscript:
1. Substantial contributions to the conception or design of the work; or the acquisition, analysis, or interpretation of data for the work; AND
2. Drafting the work or revising it critically for important intellectual content; AND
3. Final approval of the version to be published; AND
4. Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Contributors who meet fewer than all 4 of the above criteria for authorship should not be listed as authors, but acknowledged as per the guidelines ICMJE guidelines for non-author contributors as described here.


An abstract must be included with each paper, and should not exceed 250 words.


Follow the abstract with 3-5 key words. For indexing; terms not contained in the title are preferred.


The introduction should not exceed 600 words.


The discussion section should be as concise as possible,preferably less than 1600 words. Extensive coverage of the literature is discouraged.


Keep tables as few and as simple as possible. Each table should be typed a separate Word file and included at the end of the text. The title of the table should appear above and the detailed explanation of its contents (if necessary) below the body of the table. Use horizontal lines only above and below column headings and at the bottom of a table: do not use vertical rules or horizontal rules within the table body. Number tables consecutively with Roman numerals. Make sure all tables are cited in the text,and that all abbreviations used are clearly spelled out. Foot notes should be designated by superscript, lowercase letters (a,b, etc.).


All illustrations should be designed for reproduction at full-text width (6 3/4 inches) or single-column width (35/16inches) with a maximum length of 9 inches. Magnification should be indicated by a micron bar or in the legend. If illustrations are multi-paneled, number and letter them left to right, top to bottom.

All figure legends should be typed (double spaced) on a separate page at the end of the text file. All abbreviations and symbols appearing on any figure must be explained in the legend. A credit line must be included for any material reproduced from a prior publication, and written permission from the previous publisher must be obtained and included with the manuscript.

Color Illustrations

Authors are encouraged to submit color illustrations that highlight the text and convey essential scientific information. Color plates will generally be published if authors defray the cost($500 each color page). In cases of exceptional need, a maximum of one color plate will be considered by the Editor-in-Chief for reproduction free of charge, subject to the recommendation of the reviewers and Associate Editors.

Cover Illustrations

Authors may submit color figures for consideration as cover illustration for the issues of the volume in which the manuscript is used.


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In the text, cite references by name and date. For more than two authors, use the first surname and et al. In the final list, they should be in alphabetical order, including the complete title of the article cited, and names of all authors. Journal abbreviations should follow Index Medicus style. In the following examples notice the punctuation; do not use all capitals, do not underline.

Journal Articles:
Sinoway MP, Kitagawa K, Timsit S, Hashim GA, Colman DR. 1994. Proteolipid protein interactions in transfectants: implications for myelin assembly. J Neurosci Res 37:551-562.

Ausbel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K. 1987. Current protocols in molecular biology. New York: John Wiley & Sons. 1223 p.

Book Chapters:
Hayes TE, McKay RDG. 1993. Differentiation of cell types in the central nervous system. In: Levine AJ, Schmidek HH, editors. Molecular genetics of nervous system tumors. New York: Wiley-Liss, Inc. p 37-48.


Magnitudes of variables being reported should be expressed in numerals. Most abbreviations are used without punctuation. Examples: 1 mg, 25 mg, 50 msec. Abbreviations for commonly used substances should be those recommended by the Council of Biology Editors Style Manual: A Guide for Authors, Editors, and Publishers in the Biological Sciences, Fifth Edition (available from: The Council of Biology Editors, 11 South LaSalle Street,Chicago, IL60603-1210).

Use generic names in referring to drugs: trade names may be given in parentheses the first time a drug is mentioned, but the generic name should be used thereafter.


Proofs are e-mailed to the corresponding author,editor-in-chief,and production editor. Authors are requested to return the proofs within 48 hours of receipt, by express mail, and when requested, by fax. All manuscripts MUST include authors: Phone· Fax ·E-mail.

Reprints may be purchased at
Guidelines for Electronic Submission


Software and format . Microsoft Word 6.0 is preferred,although manuscripts prepared with any other microcomputer word-processor are acceptable. Refrain from complex formatting; the Publisher will style your manuscript according tothe Journal design specifications. Do not use desktop publishing software such as Aldus PageMaker or Quark XPress. If you prepared your manuscript with one of these programs, export the text to a word processing format.

File names . Submit the text and tables of each manuscript as separate files. Name each file with your last name(up to eight letters). Text files should be given the three-letter extension that identifies the file format. Macintosh users should maintain the MS-DOS "eight dot three" file-naming convention.


Software and format . All print reproduction requires files for full color images to be in a CMYK color space. Do not submit files as RGB. Submit illustrations as separate files from text and table files. All illustration files should be in TIFF and EPS (with preview) formats. Do not submit figures in the following formats: JPEG, GIF, Word, Excel, Lotus,Powerpoint, or PDFs.

Resolution . Journal quality reproduction will require grey scale and color files at resolutions yielding approximately 300ppi. Bitmapped line art should be submitted at resolutions yielding 600-1200 ppi. These resolutions refer to the out put size of the file; if you anticipate that your images will been larged or reduced, resolutions should be adjusted accordingly.

File names . Illustration files should be given the 2-or3-letter extension that identifies the file format used (i.e.,.tif, .eps).

Referrals to the Journal "Brain and Behavior"

This journal works together with Wiley’s Open Access Journal, Brain and Behavior, to enable rapid publication of good quality research that is unable to be accepted for publication by our journal. Authors will be offered the option of having the paper, along with any related peer reviews, automatically transferred for consideration by the Editor of Brain and Behavior. Authors will not need to reformat or rewrite their manuscript at this stage, and publication decisions will be made a short time after the transfer takes place. The Editor of Brain and Behavior will accept submissions that report well-conducted research which reaches the standard acceptable for publication. Accepted papers can be published rapidly: typically within 15 days of acceptance. Brain and Behavior is a Wiley Open Access journal and article publication fees apply. For more information please go to

Peer Review Scorecard Pilot

The Journal of Neuroscience Research is participating in Wiley's pilot of transferable peer review in which reviewers complete a standard scorecard in addition to their usual review. Authors of original research articles rejected with completed scorecards will be invited to transfer the manuscript, reviews, and scorecard to any of the other journals participating in the pilot. Authors will have the opportunity to revise their manuscript according to the review comments prior to transfer if they wish to do so. A list of the participating journals and more information about the pilot can be found here. We believe that this system of preserving original peer review for the next journal's use will decrease repetitious review, save authors reviewers and editors valuable time and significantly increase the speed to publication for many papers.

??? Production Questions ???

Production Editor
Fax: 717-738-9478 or 717-738-9479