Journal of Neuroscience Research

Cover image for Vol. 94 Issue 7

Edited By: Eric M Prager

Impact Factor: 2.594

ISI Journal Citation Reports © Ranking: 2014: 148/252 (Neurosciences)

Online ISSN: 1097-4547

Author Guidelines

General Information

The Journal of Neuroscience Research (JNR) publishes novel research results that will advance our understanding of the development, functions and diseases of the nervous system, using molecular, cellular, systems, and translational approaches. JNR features full-length papers, reviews, commentaries, and letter’s to the editor. All new manuscripts should be submitted online via our website, at


For additional tools visit Author Resources - an enhanced suite of online tools for Wiley Online Library journal authors, featuring Article Tracking, E-mail Publication Alerts and Customized Research Tools.


JNR encourages the use of ORCID, a non-profit, community-based effort to uniquely identify authors and link articles and other research activities to specific individuals. Authors have the opportunity to add their ORCID identified to their user profiles on or upon submission of an article. Once you provide your ORCID identifier, it will be tied to your profile and automatically available for future submissions. Additional information can be found at ORCID.


NIH Public Access Mandate

The Journal of Neuroscience Research is fully compliant with the NIH Public Access Mandate. For those interested in the Wiley-Blackwell policy on the NIH Public Access Mandate, please visit our policy statement.


Request Permissions

John Wiley and Sons has partnered with Copyright Clearance Center's Rights Link service to offer a variety of options for reusing John Wiley and Sons content. To request permissions for reuse of article content, please use the Request Permission option in the Article Tools box on each article abstract page.


Journal of Neuroscience Research Policies

Manuscripts must be written in American English. We strongly recommend that authors who are not native English speaks ask a colleague or for-hire editor whose native language is English to help them edit their work. The Journal staff will not be able to provide this service, and if papers are not written in easily understandable, idiomatic English, they will be returned to the authors without review. Wiley provides a special language editing service to ensure that your manuscript is ready for submission.


Measurements should be made using the metric system, and abbreviations for measurements should adhere to the meter-kilogram-second-Ampere (MKSA) international system of physical units. Abbreviations may be used extensively in the figures, and should be accompanied by a table of abbreviations used in figures. Abbreviations should be used sparingly in the text, as extensive use of abbreviations makes the work difficult to follow for non-specialists. In general, no more than about six common abbreviations should be used in the text of any one paper. Each abbreviation should be spelled out the first time it is used in the Abstract, in the Text, and in the Figure Legends or table of abbreviations used in the figures (up to three times if it is used in all three segments of the manuscript).


Publication Ethics

The authors, reviewers, and editors of the Journal of Neuroscience Research are expected to follow the standards determined by the Committee on Publication Ethics. In particular, authors should not submit manuscripts that contain previously published results, plagiarized material, fictitious results, or intentional reference omissions.


Authors should disclose related manuscripts that are under consideration or in press elsewhere, describing their relationship to the submitted manuscript and providing copies preferably at submission, and in any case upon request.


Authors should not submit manuscripts reporting essentially the same research to multiple journals. In addition, authors should not intentionally fragment research into multiple manuscripts if a single report would be more appropriate.


Breaches of these guidelines may result in the loss of publication privileges in the journal.


Scientific Misconduct Issues: Any alleged violation of any of the rules of scientific publishing ethics as defined by the Committee on Publication Ethics will be investigated confidentially in accord with standard Wiley–Blackwell procedures as outlined in our best practices guide. If the violations are found to be sufficiently serious, the Editor-in-Chief will request that the authors provide a written explanation. If the authors do not provide an explanation or the explanation is unsatisfactory, such that the journal's Editorial Team finds that the evidence clearly shows that a violation of our publishing ethics policy has occurred, the manuscript will be rejected or retracted, depending on current status. In such cases the Editor-in-Chief reserves the right to both notify the authors' institution of the violation of the journal's scientific ethics policy and impose punitive actions, e.g., a ban on publishing in the journal. The above course of action will also take effect if it is established that authors have violated any of the basic rules of ethical scientific conduct.


The Journal of Neuroscience Research employs a plagiarism detection system. By submitting your manuscript to this journal you accept that your manuscript may be screened for plagiarism against previously published work.


The Journal of Neuroscience Research endorses the view that the use of animals in research is an issue of legitimate concern, one that must follow carefully considered ethical standards. Specifically, it is required that animals used in research described in papers submitted to JNR have been acquired and cared for in accordance with the guidelines published in the NIH Guide for the Care and Use of Laboratory Animals and the Policies on the Use of Animals and Humans in Research published by the Society for Neuroscience. In addition, it is critical that all manuscripts employing animals identify whether the work that is being reported was approved by the institutional animal care and use committee at the site of the work. Any work that is done without such approval, or which is judged by the referees or the editors to involve cruelty or abuse of animals will not be published.


All manuscripts submitted to the Journal of Neuroscience Research must be submitted solely to this journal, may not have been published in any part or form in another publication of any type, professional or lay, and become the property of the publisher. No published material may be reproduced or published elsewhere without the written permission of the publisher and the author. The journal will not be responsible for the loss of manuscripts at any time. All statements in, or omissions from, published manuscripts are the responsibility of the authors who will assist the editors by reviewing proofs before publication.


The Journal of Neuroscience Research welcomes the following article type submissions:


Original Research: The Journal of Neuroscience Research welcomes original research articles from any neuroscience field. While there are no strict limits on this type of article, manuscripts should generally be between 4000 words and no longer than 6000 words. Authors should present the material clearly and completely, in the most concise and direct form possible. The introduction should be brief (typically less than 600 words) and the discussion should be restricted to issues directly relevant to the results (typically less than 1600 words). The authors should provide sufficiently detailed information in the Materials and Methods section for the observations to be critically evaluated and, if necessary, repeated. Original research articles will be peer reviewed and every attempt will be made to bring the acceptable research article to a rapid publication.


Review and Mini-Review: The Journal of Neuroscience Research welcomes scholarly reviews from experts from within any neuroscience field. Focused, critical Reviews of a wide range of forefront areas of neuroscience will be considered for publication. The preferred format for Reviews is that of a focused, topical paper that helps specialists remain up to date with the information published in their subject while being informative for the non-specialist. As such, reviews should focus on recent developments in a given field, describe current trends and as applicable methodologies, and provide a critical opinion intended for broad readership. Authors of reviews should avoid concentrating solely or preferentially on their own work. The total length, including any figures, should not normally exceed 12 manuscript pages, using the standard format for regular articles. However, exceptions will be made on a case-by-case basis. References should be carefully and critically chosen and kept to a logical minimum. Reviews, whether author-initiated or solicited by the Journal, will be peer reviewed. Every attempt will be made to bring acceptable reviews to a rapid publication. Please email the editor prior to submitting an unsolicited Review.


Commentaries/Letter's to the Editor: The Journal of Neuroscience Research welcomes commentaries and letter's to the editor that call attention to papers of particular note or provide critical comments on previous work. These manuscripts should be kept to a maximum of 1000 words and may include no more than 1 Figure/Table. Commentaries and letter's to the editor are peer-reviewed.


Associate Editors

When submitting a manuscript to the Journal of Neuroscience Research, authors must direct their manuscript to the appropriate section (Cellular and Molecular Neuroscience; Developmental Neuroscience and Developmental Disorders; Systems, Circuits, and Microcircuits; Behavior, Cognition, and Synaptic Plasticity; Metabolism, Mitochondria, and Energy Homeostasis; Neuroinflammation; Translational Neuroscience). Please also specify which of our Associate Editors you would like to evaluate your work, based on their areas of expertise.

Cellular and Molecular Neuroscience 

Scott Brady
University of Illinois at Chicago

Interests: Axonal transport, cytoskeleton, signaling pathways, myelin, Huntington’s disease, Parkinson’s disease, Alzheimer’s disease, amyotrophic lateral sclerosis

Volkan Coskun
University of California,
Los Angeles School of Medicine

Interests: Stem cells, adult neurogenesis, hippocampus, subventricular zone (SVZ), neurogenesis, differentiation, proliferation, epigenetics, DNA methylation, single cell transcriptome, neural repair

Anne Baron van Evercooren

Interests: Myelination, remyelination, cell therapy, stem cells, Schwann cells, oligodendrocytes

Yukio Yoneda
Kanazawa University Graduate School

Interests: Neuropharmacology, molecular biology, nerve chemistry, nerve pharmacology, biological system pharmaceutical science, amino acid signaling, gene expression

Developmental Neuroscience and Developmental Disorders

Rashmi Bansal
University of Connecticut Medical School

Interests: Oligodendrocytes, growth factors, neurodegenerative diseases (e.g., multiple sclerosis), transgenic models, membrane biogenesis

Li-Jin Chew
Children’s National Washington DC

Interests: Multiple sclerosis, myelination, oligodendrocyte, white matter injury, regeneration

Cristina Ghiani
University of California, Los Angeles

Interests: Neurodevelopment, neurodevelopmental disorders (e.g., schizophrenia, environmental and genetic factors), oligodendrocyte development, glia biology

Wendy Macklin
University of Colorado,
Denver Health Sciences Center

Interests: Oligodendrocyte differentiation, myelination, integrins, zebrafish, Akt, mTOR

Kazuhiro Ikanaka
National Institute of Physiological Sciences

Interests: Myelination, demyelination, glial development

Systems, Circuits, and Microcircuits

Carlos Cepeda
University of California, Los Angeles

Interests: Electrophysiology, basal ganglia, neurodegenerative disorders, synaptic transmission, epilepsy, cortical development, Huntington's disease, dopamine-glutamate interactions

Bertrand Lambolez
Universite PM Curie

Interests: Receptors, channels, synaptic transmission, neuromodulation, neuropeptides, cerebral cortex, cellular and circuit neurophysiology, electrophysiology, imaging

Joshua Plotkin
Stony Brook University

Interests: Huntington’s disease, obsessive compulsive disorder, basal ganglia, striatum, neurophysiology

Jeremy Ullmann
Boston Children’s Hospital and Harvard Medical School

Interests: Zebrafish, epilepsy, behavior, magnetic resonance imaging, brain atlas, morphometry

Behavior, Cognition, and Synaptic Plasticity

Hadley Bergstrom
Vassar College

Interests: Amygdala, striatum, synaptic plasticity, learning and memory, classical conditioning, instrumental conditioning

Larry Cahill
University of California, Irvine

Interests : Stress, memory, anxiety, emotion, hormones, sex differences

Eric Prager (Editor-in-Chief)

Interests: Status epilepticus, epilepsy, GABAA receptors, stress, fear, traumatic brain injury, amygdala, long-term potentiation, electrophysiology, synaptic transmission

Metabolism, Mitochondria, and Energy Homeostasis

Joyce Benjamins
Wayne State

Interests: Oligodendroglia, neuroimmunology, neurodegeneration, glycolipids, signaling pathways

Mary McKenna
University of Maryland School of Medicine

Interests: Hypoxic-ischemic injury (H/I), neuronatal H/I injury, neurodevelopment, magnetic resonance spectroscopy, diffusion weighted imaging, diffusion tensor imaging, magnetic resonance spectroscopy

Aurora Pujol Onofre

Interests: Neurodegeneration, oxidative stress, mitochondria dysfunction, leukodystrophies, rare diseases, mouse models, peroxisomes, comparative genomics, integrative-omics

Arne Schousboe
University of Copenhagen

Interests: Antiepileptic drugs, cell culture, GABA-mediated neurotransmission


Pierre Gressens

Interests: Excitotoxicity, neurodegeneration, cytokines, maternal stress, neuroprotection

J Regino Perez Polo
University of Texas Medical Branch

Interests: Responses to CNS trauma, cell death mechanisms, aging and Alzheimer’s, organelle routing, systems biology, transcription factor regulation

Kyoungho Suk
Kyungpook National University

Interests: Glia, Neuroinflammation, Neurodegeneration

James Waschek
University of California, Los Angeles

Interests: CNS development, degeneration, injury, repair, brain tumor pathogenesis, neuroinflammation, vasoactive intestinal peptide (VIP), pituitary adenylate cyclase activating peptide, maternal inflammation-induced perinatal white matter disease, immunofluorescence, confocal microscopy, microarray technology, bioinformatics

Translational Neuroscience 

Jerome Badaut
University of Bordeaux

Interests: Neurovascular unit, blood brain barrier, astrocytes, traumatic brain injury, stroke

Ernesto Bongarzone
University of Illinois at Chicago

Interests: Myelination, oligodendrogenesis, neurogenesis, axonopathies, membrane microdomains, Krabbe disease

Jean de Vellis (Editor Emeritus)
University of California,
Los Angeles School of Medicine

Interests: Gene expression, neuronal and glial cell interaction, growth factors, neurotrophins (e.g., NGF, BDNF, NT3), glucocorticoid hormones, neurotransmitters, cytokines, myelin regeneration, oligodendrocytes, astrocytes, microglia

Douglas Feinstein
University of Chicago

Interests: Multiple sclerosis, neuroinflammation, astrocytes, myelin

John Kessler
Northwestern University Medical School

Interests: Stem cell biology, gliogenesis, neurogenesis, spinal cord injury, neurological disorders

Hideyuki Okano
Keio University School of Medicine

Interests: Neural stem cells, adult neurogenesis, DNA microarray, ChIP-sequencing, transgenic models

General Instructions

Manuscripts must be submitted in American English, and be type written, paginated, and double-spaced throughout. Material should be divided into logically organized sections with all headings and sub-headings clearly delineated. Papers not following the indicated format may be returned. All manuscripts must include the following elements. They should be submitted with standard file name extensions in the following order:


Text of paper. The text of the paper should be prepared in 12 point Times Roman or Arial font, with a line of 6 or 6.5 inches (155–170 mm) width. Spelling for non-technical terms should be as recommended in the current Webster’s International Dictionary. For anatomical terms, the anglicized form of the word should be used (not Latin) whenever possible. Please avoid slang, colloquialisms, and laboratory jargon, especially in the title of the paper. The manuscript should contain a Title Page (including acknowledgments for support), Abstract, Significance Statement, Introduction, Materials and Methods, Results, Discussion, Conflict of Interest Statement, Author’s roles, Other Acknowledgments, Literature Cited, Footnotes, and Figure Legends, in that order. The file should be named with the last name of the first author-text. Text files should be in Word (.doc or .docx) format.

Title Page:

The title page should contain the title of the paper. Abbreviations should not be used. Please include names of species used when possible. Additionally, the title page should contain the following:

1.     Names of all authors and affiliations. Please use full names without degrees or titles. Each author name should carry a superscript number, assigned in ascending numerical order, to indicate institutional affiliation. Authors should include all individuals who contributed to the conception and design or to the analysis and interpretation of the work. Purely technical contributions or providing materials or equipment generally does not merit authorship. All authors must agree to be listed, and to the order of listing. Authorship should be discussed before an article is written. Contributors meeting the following criteria for authorship, as recommended by the ICMJE, must be listed as authors of the manuscript. Contributors who meet fewer than all four of the above criteria for authorship should not be listed as authors, but acknowledged as per ICMJE guidelines for non-author contributors, described here:

a.      Substantial contributions to the conception or design of the work; or the acquisition, analysis, or interpretation of data for the work; AND

b.     Drafting the work or revising it critically for important intellectual content; AND

c.      Final approval of the version to be published; AND

d.     Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

2.     Institutional Affiliation. These should be in the same order as the numbers in the authors’ superscripts, and should include Department, Institution, City, State or Province if applicable, Mail Code, and Country.

3.     Abbreviated title, or running head, not to exceed 50 characters.

4.     Name of Associate Editor to whom the manuscript is being submitted.

5.     Key words, including 3–6 words or phrases that are included in the text but not in the title of the paper that identify its content. Resource Identifiers (RRIDs) must also be listed as keywords as mentioned above in the section entitled "Resource Identification Initiative".

6.     Corresponding author, address, phone, fax, and email addresses.

7.     Support or grant information should be provided in a footnote on the title page and should include the grant sponsor and number.


The abstract should be concise, consisting of 250 words or less. It should frame the biological problem that the paper addresses, indicate the method of approach and species of animals used, and provide a brief summary of the results and conclusions. It should be intelligible without reference to the rest of the paper. Abbreviations should be used sparingly in the abstract and should be spelled out the first time they are used. References to the literature should be avoided in the Abstract, but if used, must include the full reference. 


Significance Statement:

All original research articles, reviews, and commentaries must include a statement of significance. This feature is a part of the article format and will appear online and in the print issue of the journal. Authors must submit, in the main text of the document, a 100-word-maximum statement about the significance of their research paper written at a level that is understandable to the general public and to scientists outside their field of specialty. This statement will be distinct in purpose from the abstract, with the primary goal of broadly explaining the relevance and importance of this work and how this work contributes to different diseases.


The introduction should frame the scientific issues that motivate the study. It is not enough simply to identify a known pathway or its neurotransmitter in a different species. For papers to reach a publishable level of priority, the authors must make the case for how their ideas illuminate some principles of neuroscience. Use of animals from different species should be justified in terms of understanding how differences in their adaptations help to elucidate the structure and function of the nervous system, not as an excuse for repeating work that has already been done in other species. The introduction should not exceed 600 words.

Materials and Methods:

The animals, supplies, and equipment used should be described in detail. For animals it is important to define species, strain, sex, age, supplier, and numbers of animals used (as well as distribution of animals across groups). If genetically modified mice are used, it is critical to specify the genetic background, including the generation since the founder and the number of backcrosses (if applicable) to an inbred strain.

It is critical that all manuscripts employing animals identify whether the work that is being reported was approved by the institutional animal care and use committee at the site of the work. Any work that is done without such approval, or which is judged by the referees or the editors to involve cruelty or abuse of animals will not be published.

The sources of all materials and equipment must be identified. For chemical probes it is important to include the exact sequence of the nucleic acids or peptides against which the probe was raised. Otherwise, the work is inherently not repeatable. For antibodies, please prepare a table listing in the first column the name of the antibody; in the second column the exact structure of the immunogen against which the animal was immunized (note that a vague reference to a part of the molecule is not acceptable); in the third column the manufacturer, catalog or lot number, the RRID (see Resource Identification Initiative section below), species it was raised in, and whether it is a monoclonal or polyclonal antibody; in the fourth column the concentration at which the antibody was used. In the text of the Methods section, include a section titled Antibody Characterization, in which there is a brief paragraph for each antibody used, explaining how it was characterized, and providing appropriate controls. Characterization includes information that assures the reader that the antibody specifically recognizes its supposed target. This can include Western blots (for which it is necessary to indicate the species and tissue examined, and the pattern of bands stained and their molecular weight), radioimmunoassay or ELISA, or other types of experiments. Controls may include reabsorption with the original antigen; attempts to stain tissue from knockout animals; comparisons with the in situ hybridization pattern, etc. For antibodies used as tissue markers (rather than to establish a novel and unique localization of the antigen), it is sufficient to indicate that the antibody stains the appropriate pattern of cellular morphology and distribution as demonstrated in previous publications, which should be cited. Note that we need the manuscript to actually give the evidence for characterization and specificity. Simple references to other papers where characterization has been done are not acceptable.

Although the use of an antibody database is new to the Journal of Neuroscience Research, it has been successfully used in papers in the Journal of Comparative Neurology since 2006. A database has been set up to look for antibodies that have met the stringent standards of JCN, and to find papers that contain information on the characterization of those antibodies.  For more information on the antibody database and RRID’s please click here.

For digital photography, it is necessary to identify what forms of digital manipulation were employed in preparing the images (e.g., adjusting brightness, contrast, sharpness, evenness of illumination, etc.). The purpose of figures is to present to the audience an overview of the observations, not to provide a faithful recreation of artifacts. Thus, images can be adjusted and even retouched, but if they are manipulated in any way, it is important to identify those changes in the Methods section (or in the figure legend if it applies to a single image).


The results of the study should be laid out in a series of declarative paragraphs. Often the reporting of the results can be clearer if broken down into subsections. All figures and tables must be cited in the text, and must be numbered in the order of their text citation. The Results section should not include long passages about the rationale for each experiment (which belong in the Introduction) or the methods used (which belong in the Materials and Methods), nor should it include justification or discussion of the results (which belong in the Discussion section). In general, if a passage in the Results involves the use of numerous citations, the authors ought to consider whether that material better belongs in the Introduction or the Discussion.

Articles containing statistical analyses should clearly state the name of the statistical test, the n value for each statistical analysis, the comparisons of interest, and justification for the use of the test. It should be clear what statistical test was used to generate every P value. Moreover, the authors must include the values from the appropriate statistical test (e.g., F(x,x) = xx; n = x; P = x). If the tests violate any assumptions, the authors must provide this information. The n must be reported at the start of the study and for each analysis thereafter. In addition, the test must be clearly identified as one- or two-tailed and the actual P values must be given for the primary analysis. Any unusual or complex statistical methods must be clearly defined and explained for the wide readership. Any data exclusions, discrepancies in the value of n between analyses, method of treatment assignment, and data transformations must be clearly described and justified.



The Discussion should begin with a statement of the important findings of the paper. Subsequent sections can address technical issues, analysis of the results, and the implications of the work. Again, it is often helpful to break down the Discussion into subsections that focus on particular topics. The Discussion should not contain a summary or resume, as this is the function of the Abstract. However, it is proper to include a section that draws together the results and expands upon conclusions that may be drawn from the work. The discussion section should be concise, preferably less than 1600 words. Extensive coverage of the literature is discouraged.

Other acknowledgments:

These may include thanks to technicians or colleagues who have helped with the work or provided materials. All who are acknowledged must be informed of that fact by the authors, and agree to be listed.


Conflict of Interest Statement:

All authors must disclose any known or potential conflict of interest including any financial, personal or other relationships with other people or organizations within three years of beginning the submitted work that could inappropriately influence, or be perceived to influence, their work. If there is no identified conflict, state so. This declaration must be made within a Conflict of Interest Statement section of the main article and will be published in the journal.


Role of Authors:

All authors listed on the paper must have contributed significantly to the elaboration of the paper and/or to the research that led to preparation of the manuscript. The role of each author must be described in a paragraph after the Acknowledgements and the Conflict of Interest disclosure. It can adopt the following format:

“All authors had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Names or Initials. Acquisition of data: Names or Initials. Analysis and interpretation of data: Names or Initials. Drafting of the manuscript: Names or Initials. Critical revision of the manuscript for important intellectual content: Names or Initials. Statistical analysis: Names or Initials. Obtained funding: Names or Initials. Administrative, technical, and material support: Names or Initials. Study supervision: Names or Initials.”


Literature Cited:

All references cited in the text (and only those cited in the text) should be included. In the text, references should be cited by authors’ names and year of publication. One or two authors should be cited by name; for three or more, the first author is cited followed by et al.:

    …studies by Doe (2003) reveal…

    …studies by Doe and Jones (2003) reveal…

    …studies by Doe et al. (2003) reveal…


References that are not cited by name should be included at the end of a phrase or sentence in parentheses, in chronological order, separated by semicolons, except for two or more papers by the same authors, which should be separated by commas. References to more than one paper in the same year should be designated by letters:
…(Doe, 1999; Doe and Jones, 2002; Jones et al., 2003a, 2003b).


The citations in the Literature Cited should be in alphabetical order by authors, then chronological order by year. For papers with identical authors and years, the citations should be alphabetical by journal, and then chronological by appearance in the journal. Authors are referred to recent papers published in the Journal for specifics of citation style for different types of communications. The Journal of Neuroscience Research citation formats are contained within Endnote and Reference Manager, and can be downloaded from EndNoteor RefWorks.


Abbreviations of journal names should conform to Index Medicus. Only papers that are in press (accepted for publication in final form) or in print may be cited. Work that is “in preparation” or “submitted” should be cited in the text as personal communications. The person who is cited must give permission for this usage. It is the responsibility of the authors to obtain this permission before the paper is submitted.


Resources Cited:

Please cite all resources used within the text as described below in the section entitled "Resource Identification Initiative”.


Table Files:

Authors are encouraged to prepare tables using the table tool in Word. Each table should be contained in a separate file, and the files should be named by table number (i.e., Table 1, Table 2…). Tables that require extensive formatting may be submitted as image files, using .tif format, but should be named by table number.


Figure files:

Each file should contain a single figure and be named figure number (i.e., Figure 1, Figure 2, etc.), and should be in TIFF (.tif) or EPS (.eps) format only, at a resolution of 300 dpi.  Please do NOT use JPEG (.jpg), GIF (.gif), PowerPoint (.ppt), Portable Document (.pdf), or Word (.doc) files, or proprietary file types that are not interchangeable among programs (e.g., Illustrator, Canvas, or Photoshop).


Graphical Abstract:

This feature is a part of the online article format and will appear in the online Table of Contents of each issue of the journal. The graphical abstract provides readers with a visual representation of the conclusions and an efficient way to appreciate the key finding and main message of the work. Please upload a short statement of 50 words or less (1-2 sentences), together with an illustration (TIFF or EPS) describing the context and significance of the findings for the broader JNR readership to attract the attention of non-specialists. The text file should be of .doc format and be designated as the Graphical Abstract Text filetype in ScholarOne Manuscripts. The intent of this text is to summarize the key results and major conceptual advance of the article, providing readers with an efficient understanding of the main take-home message of the paper, without including extensive experimental details. The image should be a single image not containing multiple panels. It is meant to represent one key aspect of the results. The selected image should also be a figure or part of a figure that is included in the paper, but can also be an explanatory diagram of the paper's major findings. This is not a vehicle to publish supplementary information not directly reported in the paper. To prepare the image, select an image or graphic that is easy to read and as much as possible devoid of cluttering items, conveying clear, non-speculative, visual information about the biological context of the findings. Labels, while useful, must be kept to a minimum. The image should be provided in one of the following height and width configurations: 400 x 300 pixels, 300 x 400 pixels, or 400 x 400 pixels, and at a maximal resolution of 72 dpi. Please use Arial or Helvetica font with a size of 10–12 points; preferred file types are EPS and TIFF. When uploading, please designate the image as Graphical Abstract Image in ScholarOne Manuscripts.


“Resource Identification Initiative”

The Journal of Neuroscience Research is now participating in the Resource Identification Initiative, which aims to promote research resource identification, discovery, and reuse. This initiative, led by the Neuroscience Information Framework and the Oregon Health & Science University Library, provides unique identifiers for antibodies, model organisms, and tools such as software and databases. These IDs, called Research Resource Identifiers (RRIDs), are machine-readable and can therefore be used to search for all papers in which a particular resource was used and to increase access to critical data to help researchers identify suitable reagents and tools.


As part of this pilot project, we ask authors to use RRIDs to cite the resources used in your research where applicable in the text, exactly as you would a regular citation or Genbank Accession number. For antibodies, we ask that you please include in your citation the vendor, catalogue number, and RRID both in the text upon first mention in the methods section, and in your antibody table (see Materials and Methods section). For software tools and databases, please provide the name of the resource followed by the resource website if available, and the RRID. For model organisms, the RRID alone is sufficient.


We also ask that you please include the RRIDs in the list of keywords associated with your manuscript.


To Obtain Research Resource Identifiers (RRIDs):

1.     Use the Resource Identification Portal, created by the Resource Identification Initiative Working Group.

2.     Search for your research resource (please the section titled “Search Features and Tips” for more information).

3.     Click on the “Cite This” button to obtain the citation and insert the citation into your manuscript text.


If you have a resource that is not found within the Portal, we encourage you to register the resource with the appropriate resource authority. Information on how to do this is provided in the “Resource Citation Guidelines” section of the Portal.


If you experience any difficulties obtaining identifiers, please contact for assistance.


Example Citations:

1.     Antibodies: "Wnt3 was localized using a rabbit polyclonal antibody C64F2 against Wnt3 (Cell Signaling Technology, Cat# 2721S, RRID: AB_2215411)"

2.     Model Organisms: "Experiments were conducted in c. elegans strain SP304 (RRID: CGC_SP304)"

3.     Tools, Software, and Databases: "Image analysis was conducted with CellProfiler Image Analysis Software, V2.0 (, RRID: nif-0000-00280)"


Cover Illustrations

Authors may submit high-resolution color figures for consideration as cover illustration for the issues of the volume in which the manuscript is used. This would have to be produced free of labels such as scale bars, etc., and formatted to 612 x 810 points (2550 x 3375 pixels) at a resolution of 300 DPI. We will also require a brief caption for the image (100 words or less) to be supplied as a word document. If you choose to supply these items, the image will be featured on the cover of the journal issue in which your manuscript will be assigned and published.


Figures and Tables

Figure Legends and Table of Abbreviations Used in the Figures:
The figure legends should be self-explanatory, without referring to the text. They should identify the material that is being illustrated, what is shown, and its significance. Abbreviations used in the figure legends should be used sparingly, and should be spelled out the first time they are used. Abbreviations used in the figures should be included either in the figure legend for that figure (e.g., INC, inferior colliculus; OC, optic chiasm; ZI, zona incerta…) or should be included in a table of abbreviations used in the figures:


Note that when only a few abbreviations are used in the figures, it is usually better to include them in the relevant figure legends, but when extensive use is made of abbreviations, as in labeling of sections through multiple levels of the brain, a table is usually preferred.


Figures should be numbered in the order that they are cited in the text, and presented in that order after the text of the paper. The first time any panel from a figure is cited, that entire figure is considered to have been cited (i.e., the panels should be laid out in an order that is reasonable for that plate, and do not have to be cited in order in the text). Each figure should be submitted in a separate electronic file. All of these files should be formatted at 300 dpi. Please do not submit figures at greater than 300 dpi, as neither our printed page nor .pdfs can display the added resolution, but the files may be too large to load properly into the .pdf used for review. Figures should be designed for reproduction at full-text width (6 ¾ inches) or single-column width (3 5/16 inch) with a maximum length of 9 inches. Magnification should be indicated by a micron bar or in the legend. If illustrations are multi-paneled, number and letter them left to right, top to bottom. Figures should be presented in portrait orientation (not in landscape), as most images will be viewed on a computer screen.


Figures should be presented in a plain and unadorned style, on a white background. Panels should not be set off by boxes or other edging, and lettering and images should not have gratuitous effects such as highlighting, three dimensional edging, shading, etc. Lettering for panel designators should be 3–6 mm in height, and lettering within a figure 2–4 mm in height. Larger lettering is unnecessary and appears cluttered; smaller lettering may not be legible on a computer screen. Either a Times Roman or Arial font is acceptable, but the same font and type size should be used throughout the figures for a single paper.


Line drawings should use a professional quality graphics program capable of providing smooth, clean lines that are not jagged. Where possible, figures should consist of black lines and lettering against a white background. Color may be used to differentiate specific features of a drawing, but should be scientifically necessary (i.e., needed to differentiate the different parts of the image, such as different lines in a graph or different labels mapped against a brain section).


Photomicrographs should be framed and cropped to show the material to its best advantage. The brightness, contrast, sharpness, and evenness of illumination may be adjusted, although this must be indicated in the Materials and Methods or in the figure legends. The resolution of all photomicrographs must be at least 300 dpi, and they should be provided in TIF or EPS format. All print reproduction requires files for full color images to be in a CMYK color space. Do not submit files as RGB. Submit figures as separate files from text and table files. Do not submit figures in the following formats: JPEG, GIF, Word, Excel, PowerPoint, or PDFs.


Authors are encouraged to submit color illustrations that highlight the text and convey essential scientific information. Color plates will generally be published if authors defray the cost ($500 per figure). In cases of exceptional need, a maximum of one color plate will be considered by the Editor-in-Chief for reproduction free of charge, subject to the recommendation of the reviewers and Associate Editors.


Graphs should be produced at a resolution of 600–1200 dpi and use a legible font (such as Arial or Helvetica for the labels. Remove all background shading, horizontal and vertical lines or frames around the plots. Simply importing graphics from Excel is not acceptable as the quality of raw Excel graphs is insufficient. The use of 3-dimensional graphs is discouraged as they can be confusing and often fail to convey the proper information to the reader; these should be used only if absolutely justified.


Tables should be numbered in order of appearance in the text, and presented in numerical order. Each table should be identified by number and should have a title. Each table should be uploaded as a separate Word file. The title of the table should appear above and the detailed explanation of its contents (if necessary) below the body of the table. Use horizontal lines only above and below column headings and at the bottom of a table: do not use vertical rules or horizontal rules within the table body. Number tables consecutively with Roman numerals. Make sure all tables are cited in the text, and that all abbreviations used are clearly spelled out. Footnotes should be designated by superscript, lowercase letters (a, b, etc.)


Supplementary materials:

The Journal of Neuroscience Research does not accept electronic supplements. If they are deemed important for the points made by the paper, these figures or tables must be integrated within the main text. Exceptions are made for extensive lists of genes or sequences, extensive tabular datasets or raw quantitative materials that authors wish to make available to the scientific community, or very large photographic documentation of results that is necessary for the study and cannot be summarized in the photographic plates included in the article, and movie files. Movies files should be submitted in .AVI, .MPG, .MOV, .WMV, or .RM. Note that electronic supplements must not exceed 500 MB. If you submit supplementary files, please also supply a separate Word (.doc) file containing the figure legends for the supplemental material.


Referrals to the Open Access Journal, Brain and Behavior

The Journal of Neuroscience Research will provide authors of good quality research that is outside the Journal's scope or that cannot be published in the Journal due to limited space with a referral and option to transfer their manuscript to Wiley’s Open Access Journal, Brain and Behavior. Authors will be offered the option of having the paper, along with any related peer reviews, automatically transferred for consideration by the Editor of Brain and Behavior. The transfer will occur on-line and guarantee the anonymity of the peer-review process. Authors will not need to reformat or rewrite their manuscript at this stage, and publication decisions will be made a short time after the transfer takes place. The Editor of Brain and Behavior will accept submissions that report well-conducted research, which reaches the standard acceptable for publication. Accepted papers can be published rapidly, typically within 20 days of acceptance. Brain and Behavior is a Wiley Open Access journal and article publication fees apply.  For more information please go to


Peer Review Scorecard Pilot

The Journal of Neuroscience Research is participating in Wiley's pilot of transferable peer review in which reviewers complete a standard scorecard in addition to their usual review. Authors of original research articles rejected with completed scorecards will be invited to transfer the manuscript, reviews, and scorecard to any of the other journals participating in the pilot. Authors will have the opportunity to revise their manuscript according to the review comments prior to transfer if they wish to do so. A list of the participating journals and more information about the pilot can be found here. We believe that this system of preserving original peer review for the next journal's use will decrease repetitious review, save authors, reviewers and editors valuable time and significantly increase the speed to publication for many papers.

Neuroscience Peer Review Consortium

The Journal of Neuroscience Research is a member of the Neuroscience Peer Review Consortium. The Consortium is an alliance of neuroscience journals that have agreed to accept manuscript reviews from each other. If you submit a revision of your manuscript to another Consortium journal, we can forward the reviews of your manuscript to that journal, should you decide this might be helpful. You can find a list of Consortium journals and details about forwarding reviews at  .


Manuscript Production  


Proofs are emailed to the corresponding author, editor-in-chief, and production editor. Authors are requested to return the proofs within 48 hours of receipt.


Reprints may be purchased at If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.


For authors signing the copyright transfer agreement

If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:


CTA Terms and Conditions


For authors choosing OnlineOpen

If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):

1.     Creative Commons Attribution License OAA

2.     Creative Commons Attribution Non-Commercial License OAA

3.     Creative Commons Attribution Non-Commercial -NoDerivs License OAA


To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services and visit


If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit: