Study of both fingerprint and high wavenumber Raman spectroscopy of pathological nasopharyngeal tissues
Wei Huang, Shanshan Wu, Maowen Chen, Liqing Sun, Yongzeng Li, Meizhen Huang, Shaohua Huang, Zhihong Xu, Rong Chen and Haishan Zeng
Article first published online: 14 APR 2015 | DOI: 10.1002/jrs.4684
Both fingerprint (FP, 800–1800 cm−1) and high wavenumber (HW, 2700–3100 cm−1) Raman spectroscopy were utilized to evaluate the discrimination feasibility of nasopharyngeal non-cancerous and nasopharyngeal cancer (NPC) tissue. The results demonstrate that both FP and HW Raman spectroscopy have the potential for diagnosis and detection in early nasopharyngeal carcinoma, and HW Raman spectroscopy may improve the discrimination of NPC tissue compared with FP region alone, providing a promising diagnostic tool for discriminating nasopharyngeal non-cancerous from NPC tissue.