Muscle & Nerve

Cover image for Vol. 54 Issue 2

Edited By: Lawrence H. Phillips II, MD

Impact Factor: 2.713

ISI Journal Citation Reports © Ranking: 2015: 73/192 (Clinical Neurology); 128/256 (Neurosciences)

Online ISSN: 1097-4598

Author Guidelines

NIH Public Access Mandate
For those interested in the Wiley-Blackwell policy on the NIH Public Access Mandate, please visit our policy statement

For additional tools visit Author Resources - an enhanced suite of online tools for Wiley InterScience journal authors, featuring Article Tracking, E-mail Publication Alerts and Customized Research Tools.

Author Guidelines

Manuscript Types: The Journal is composed of ten sections.

Manuscript Type



Key Words

Word Count


Research Articles

(150 words) Structured headings: Introduction, Methods, Results, Discussion

less than 10 is preferred

5 key words below the abstract page pertaining to all major points of the contribution

6000 words

Present original clinical and laboratory research and related topics.

Short Reports

(150 words) Structured headings: Introduction, Methods, Results, Discussion

Only 1 figure or table

5 key words below the abstract page pertaining to all major points of the contribution

1000 words

Provide preliminary communications of new data or research methods.

Invited Review Articles

(150 words) Does not need to be structured unless requested by Editor

less than 10 is preferred

5 key words below the abstract page pertaining to all major points of the contribution

Generally less than 6000 words. Exceptions after approval by the Editor

Describe current topics of importance and are usually solicited by the Editor.



Generally no figures or tables

5 key words below the abstract page pertaining to all major points of the contribution

no more than 2000 words, with up to 12 references

Either free-standing brief commentary or discussion of an article published in the same issue of the Journal. Solicited by the Editor.

Case of the Month

(150 words) Structured headings: Introduction, Methods, Results, Discussion

1 table and up to 4 figures.

5 key words below the abstract page pertaining to all major points of the contribution

2,000 to 3,000 words

Presentation of rare or illustrative studies of noteworthy neuromuscular disorders

Noteworthy Cases

Letter to the Editor and Replies


1 figure or table

5 key words below the abstract page pertaining to all major points of the contribution

500 words

Noteworthy Cases: Submitted in the form of a Letter to the Editor

Letters: Comment on papers published in this journal or other relevant matters. Subtitles should not be used, and any acknowledgments should be included in the body of the letter.

Book Reviews

(150 words) Does not need to be structured

Solicited by the Editor. Publishers should send one of each book to the editorial office in Charlottesville, VA. Selection of books and reviewers is at the sole discretion of the Editor.

Issues and Opinions

(150 words) Does not need to be structured unless requested by Editor

1 table and up to 4 figures.

5 key words below the abstract page pertaining to all major points of the contribution

2,000 to 3,000 words

Deal with current topics related to etiology, pathogenesis, electrodiagnosis or therapy of neuromuscular disorders. The articles need not be data based. We welcome expression of novel hypotheses and reviews of controversial subjects. When appropriate, opposing views will be presented in the same section usually prepared by one of our editors or an expert identified by the Editorial Office.

Manuscript Submission

Manuscripts must be submitted electronically. For complete instructions on how to do so, go to and follow the instructions for creating an account and submitting a manuscript. When submitting your article to Manuscript Central, upload your text, figure legends, and tables as one file in the manuscript. This file and the figures will be combined into a single PDF document for the peer review process.

If you are updating a file, please delete the original version and upload the revised file. To designate the order in which your files appear, use the dropdowns in the "order" column below. View your uploaded files by clicking on HTML or PDF. When you are finished, click "Next."

General correspondence concerning a MUSCLE & NERVE submission may be directed to the editorial office:


If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.

NIH Public Access Mandate

For those interested in the Wiley-Blackwell policy on the NIH Public Access Mandate, please visit our policy statement


OnlineOpen is available to authors of articles who wish to make their article freely available to all on Wiley Online Library. When appropriate, Wiley submits OnlineOpen articles to PubMed Central. In addition, authors of OnlineOpen articles are permitted to post the final, published PDF of their article on a website, institutional repository or other free public server, immediately on publication. With OnlineOpen the author, the author's funding agency, or the author's institution pays a fee to ensure that the article is made open access.

OnlineOpen is fully compliant with open access mandates – meeting the requirements of funding organizations where these apply, including but not limited to:

 Charity Open Access Fund (COAF): Arthritis Research UK, Breast Cancer Campaign, the British Heart Foundation, Cancer Research UK, Leukaemia & Lymphoma
 The Wellcome Trust
 Telethon Italy
 National Institutes of Health (NIH)
 The Howard Hughes Medical Institute (HHMI)

For more information regarding OnlineOpen and Copyright, please visit:

For additional Wiley Open Access information, please visit:


Sources. Webster's Third New International or New Collegiate dictionaries (G. & C. Merriam Co., Springfield, MA) should be used for spelling and hyphenation of nonmedical terms, and Dorland's Illustrated Medical Dictionary (WB Saunders, Philadelphia) for medical terms. Good sources for general style (grammar, punctuation, capitalization, etc.) are: A Manual of Style (The University of Chicago Press, Chicago) and The Elements of Style , by Strunk and White (Macmillan Publishing Co., New York). For units of measure, symbols and nomenclature for biochemistry and biology, use the CBE Style Manual (American Institute of Biological Sciences, Arlington, VA) and for medicine, use the AMA Stylebook and Editorial Manual (American Medical Association, Chicago).Standard United States spellings will be used in all publications.

Numbers. Use numerals for all units of measure and time, and for all enumerations (e.g., 3 mm, 55%, 2 hours, 9 months, 20 years, 1 of 19 patients). SI unit conversions should appear in parentheses following all units of measure. Spell out numbers beginning a sentence.

Abbreviations. Abbreviations should be kept to a minimum, because their use often confuses readers who are not familiar with the subject matter. Only standard abbreviations, as listed in theCBE Style Manual and the AMA Stylebook and Editorial Manual (see above), may be used without definition. Terms appearing frequently within a paper may be abbreviated, but should be spelled out at first citation, with the abbreviation in parentheses. The term "MRI" for magnetic resonance image is an exception and need not be spelled out at first citation.


• Word format preferred
• Electronic versions in ASCII or PDF are not acceptable
• Double Space entire manuscript, including reference section
• Organize manuscript in the following order, with each component beginning on a separate page and with a running title and page number in the upper right hand corner of each page

o Title page (page 1)

 Article Title (80 spaces Maximum)
 Authors’ full name (first name, middle initial, surname) and graduate degree (no more than 2)
 Author Affiliations (name of department if any, institution, city and state or country where work was done) **Authors with multiple affiliations should provide only their primary affiliation.
 Acknowledgments if applicable (grant support and individuals who were of direct help in preparation of the study
 Name/address and email address of the author to whom reprint requests are to be sent
 Running title (30 spaces Maximum)
 If part or all of the material is contained within a presentation made at a national meeting, the organization, city, and date of the presentation should be included as a footnote, but details of any abstracts should not be cited here.

o Abstract (page 2)

 Include title of article
 No more than 150 words
 Depending on type of article, the abstract should include sections labeled: Introduction, Methods, Results, Discussion. For basic research publications a statement of clinical relevance is encouraged. Authors who wish to have additional information about the structured abstract format are referred to the National Library of Medicine website: ( and to an article that reviews the subject: (Harbourt AM, Knecht LS, Humphreys BL. Structured abstracts in MEDLINE, 1989-1991. Bull Med Libr Assoc. 1995;83:190-195).
 Key Words: The authors should provide 5 key words below the abstract page pertaining to all major points of their contribution. This will help index the article for reference citations. Authors are suggested to refer the below link for adding key words: Search Engine Optimization: For Authors

o Text (starts on page 3)

 Organized in the following format; Introduction, Materials and Methods, Results, and Discussion. Other descriptive headings and subheadings may be used if appropriate. Every effort should be made to avoid jargon, to spell out all nonstandard abbreviations the first time they are mentioned, and to present the contents of the study as clearly and as concisely as possible.
 The methods, apparatus (including manufacturer's name and address), and procedures should be identified in sufficient detail to allow other investigators to reproduce the results. References should be given for all discussions of previous studies and for all nonstandard methods used. For experiments in which humans were studied, indicate whether the procedures followed were in accord with the standards of the Committee on Human Experimentation of the institution in which the experiments were done or in accord with the Helsinki Declaration of 1975. For experiments on animals, indicate whether the institution's or the National Research Council's guide for the care and use of laboratory animals was followed. For drugs and chemicals, the generic name should be used at first mention and, preferably, thereafter. Trade name may appear in parentheses and should be capitalized. Patients' names, initials, or hospital numbers should not be used.
 Be sure that all references and all tables and figures are cited within the text. The tables and figures should be numbered according to the order in which they appear. Data appearing in tables or figures should be summarized, not duplicated, in the text. All data cited in the text should be checked carefully against the corresponding data in the tables to ensure that they correspond, and all names cited in the text should be checked carefully against the references to ensure that the spelling is correct. Any ambiguous symbols (e.g., the letter "O" versus the numeral "0," the letter "I" versus the numeral "1") should be identified. Tables should be of a size that can be printed in a vertical format on the page, thus the width should be no more than 6 inches.

o Abbreviations. All abbreviations used in the text should be listed and defined in alphabetical order on a separate page. This list should appear just before the references

o References.

 Double-spaced
 Listed and numbered in the order of citation and number them accordingly.
 Identify references in the text, tables, and legs by Arabic numerals typed as superscripts.
 Include ALL author names (surnames followed by initials, use "et al" after the sixth author in the case of multi-authored works),
 Include the title of the article with the same spellings and accent marks as in the original
 Include the journal title abbreviated as it appears in the Index Medicus or spelled out if it is not listed there
 Include the date of publication
 Include the volume number
 Include inclusive page numbers.
 For books be sure to include the chapter title, chapter authors, editors of the book, title of the book (including volume or edition number), publisher's name and location, date of publication, and appropriate page numbers.
• "Unpublished observations," "personal communications," and information that has been obtained from manuscripts "submitted for publication" but not yet accepted should not appear in the references but should be cited in parentheses in the text. Unpublished observations should include the authors, the year, and should be accompanied by letters of permission from all individuals cited; quotations from manuscripts that have been submitted for publication should include the authors, the title of the manuscript, and the date. Manuscripts that have been accepted for publication but have not yet been published may appear in the references. Include the authors, manuscript title, and name of journal, followed by "to be published" in parentheses.

Examples of the correct format are as follows:

Article Type


Journal Article

Franssen H, Straver DC. Pathophysiology of immune-mediated demyelinating neuropathies-Part II: neurology. Muscle Nerve 2014;17:4–20.

Journal Article (use et al after 6th author)

Dispenzieri A, Kyle RA, Lacy MQ, Rajkumar SV, Therneau TM, Larson DR, et al. POEMS syndrome: definitions and long-term outcome. Blood 2003;101:2496–2506.


Pedersen J, Wallace M. 1999. Wiley Journals DTD: Guidelines for reference tagging. Available at Accessed 2002 Feb 4.


Oussalah M. Some notes on fusion of uncertain information. International Journal of Intelligent Systems 1984;19(6). Published online: April 23, 2004. DOI: 10.1002/int.20001.


Smith, J.A. 2001. How to Write Journal Guidelines. Springer: New York

Book Chapter

Katz JN. Developments in surgery for rheumatic and musculoskeletal disorders. In: Pisetsky DS, editor. The ACR at 75: a diamond jubilee. Hoboken (NJ): Wiley-Blackwell; 2009. p. 87-91.

o Tables

 Double-spaced
 Separate pages
 Word file, NOT photograph or image files
 Vertically oriented and no more than 6 inches wide
 If table must exceed 1 typewritten page, duplicate headings on the second sheet
 Numbered in the order in which they are cited in the text
 Include a title
 Every column (including the left-hand (stub) column should have a heading
 Define all abbreviations and indicate the units of measurements for all values
 Use commas for all numbers exceeding 999, and use zeros before decimals for numbers less than 1
 Orgainized so that like data are read vertically, not horizontally.
 Do not use internal horizontal or vertical lines to separate sections
 Explain all empty spaces or dashes
 Indicate footnotes to the table using the following symbols
• * (asterisk), † (dagger), ‡ (double dagger), § (section mark), (parallels), (paragraph mark), # (number sign).
• Letters of the alphabet, lower case and italic, should be used instead if there are more than 7 footnotes.
• Symbols (or letters) should appear after commas and periods, before colons and semicolons, and should be superscript.
 If data from any other source, published or unpublished, are used, obtain permission for their use and cite the source in the legend.

o Figure/Images

 TIFF or EPS file format (Tagged Image File, Encapsulated PostScript)
 Each file must include all subparts (A, B, C, etc.) to the figure. Subparts should not be uploaded individually
 Resolution
• Halftones are to be scanned at 300 dots per inch (dpi)
• Line Art is to be scanned at 1200 dpi
 Figures prepared in Word, Excel, Microsoft Publisher, Lotus 123, PowerPoint and Corel Draw are not acceptable as digital files
 If your files have been prepared in one of these formats and cannot be converted you will be required to mail high quality hard copy figures.
 All images must be saved and submitted in final size. The final figure sizes are: 1 column = 3-in. (8.25-cm) wide, 1.5 column = 5-in. (13-cm) wide, 2 columns = 6-in. (17.15-cm) wide. Figures should not exceed 8-in. (21.6-cm) in height. All cropping and manipulation must be completed before the images are submitted to the publisher.
 Avoid use of fine lines (point and below) for graphs and charts
 Use only Adobe Type 1 fonts in creating images, and limit the number for fonts used
 Do not reletter images in Photoshop. If relettering must be done, import the image into either Freehand or QuarkXPress and reletter, then make an EPS file.
 Make sure all scanned images are "clean." Look for and clean up dust specks, scratches, tape marks, and anything that is not part of the actual image. Files generated in Freehand should be saved in EPS format.
 Photomicrographs must include a calibration bar of appropriate length (e.g., 1µm, 0.1 mm, etc.) Symbols used in micrographs should contrast with the background.
 For photographs of persons, written permission from the subject must be supplied. Unless specified otherwise, the subject's eyes will be masked to prevent identification.
 Digital Figures. To ensure that your digital graphics are suitable for print purposes, please go to RapidInspector™ at . This free, stand-alone software application will help you to inspect and verify illustrations right on your computer.

o Figure Legends

 Less than 200 words
 Double spaced
 Numbered with Arabic numerals corresponding to the illustrations.
 When symbols, arrows, numbers, or letters are used to identify parts of the illustration, each should be explained clearly in the legend
 For photomicrographs, the internal scale markers should be defined and the methods of staining should be given. If the figure has been previously published a credit line should be included


Figures must be consistent in all published versions; Muscle and Nerve does not offer online-only color publication. Authors are required to pay the cost of reproducing color figures. Muscle and Nerve charges per figure, $600 for the first figure. Second, third and fourth figures are billed at $400 each.


The journal Muscle & Nerve is committed to objectivity in the collection of, analysis, and interpretation of scientific data, and to maintaining the highest ethical standards in the conduct of all research.

On the submission site, the submitting author will disclose, on behalf of ALL authors if they, or any immediate family member within the last 5 years have had any affiliations that they consider to be relevant and important with any organization that to any author's knowledge has a direct interest, particularly a financial interest, in the subject matter or materials discussed. Such affiliations include, but are not limited to, employment by an industrial concern, ownership of stock, membership on a standing committee or the board of directors, consultantships, or being publicly associated with a company or its products. Other areas of real or perceived conflict of interest include the receipt of honoraria, consulting fees, grants, or funds from such corporations or individuals representing such corporations. Such disclosure is required for every sort of article submitted to the journal, including original research, reviews, editorials, letters to the editor and any others, and will be required at the time of submission.

The simplest remedy for conflict of interest is disclosure. In the journal, disclosure will be achieved by the inclusion of a short footnote with each published article. This will not influence the editorial decision to accept or reject the manuscript. When an article is accepted for publication, the Editor will usually discuss with the authors the manner in which such information is to be represented.

Data Access. For reports of original data, at least 1 author (e.g., the corresponding or principal investigator) is expected to have full access to all the data in the study and to take responsibility for its accuracy. Readers are referred to the editorial by Rosenberg et al. (Muscle Nerve 2002;25:133–134). Such access must be confirmed on the Author Disclosure section of the submission site.