Journal of Cellular Biochemistry

Cover image for Vol. 118 Issue 9

Edited By: C. Fred Fox, Gary S. Stein, and Max M. Burger

Impact Factor: 3.085

ISI Journal Citation Reports © Ranking: 2016: 101/189 (Cell Biology); 129/286 (Biochemistry & Molecular Biology)

Online ISSN: 1097-4644

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JCB Spotlight Article

Platelet-Derived Growth Factor Regulates YAP Transcriptional Activity via Src Family Kinase Dependent Tyrosine Phosphorylation

Rory L. Smoot, Nathan W. Werneburg, Takaaki Sugihara, Matthew C. Hernandez, Lin Yang, Christine Mehner, Rondell P. Graham, Steven F. Bronk, Mark J. Truty, and Gregory J. Gores

Platelet derived growth factor inhibition decreases YAP nuclear localization and transcriptional activity. Tyrosine phosphorylation of YAP by Src family kinases determines subcellular localization in our models of cholangiocarcinoma. Inhibition of platelet derived growth factor signaling decreases cholangiocarcinoma cell viability.

Transition to Online-Only

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Wiley is delighted to announce that the Journal of Cellular Biochemistry will be available online-only as of January 2016.

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