Journal of Cellular Biochemistry

Cover image for Vol. 115 Issue 11

Edited By: C. Fred Fox, Gary S. Stein, and Max M. Burger

Impact Factor: 3.368

ISI Journal Citation Reports © Ranking: 2013: 90/185 (Cell Biology); 107/291 (Biochemistry & Molecular Biology)

Online ISSN: 1097-4644


Author Guidelines


Introducing Accepted Articles publication for Journal of Cellular Biochemistry
Papers accepted for publication in JCB will now publish online as Accepted Articles within 5-7 days after acceptance and indexed by PubMed within 48 hours of release into the public domain. The paper will be published in its final format in print and this version will also replace the Accepted Article (unedited) version online. Please note that Accepted Article publication makes it incumbent upon the authors to submit their revisions with little or no alterations necessary.

NIH Public Access Mandate
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Author Guidelines


Executive Editors
Online Submission Instructions
Article Categories
Supplementary Online Material
Copyright/Licensing

Journal of Cellular Biochemistry

The Journal of Cellular Biochemistry publishes descriptions of original research in which complex cellular, pathogenic, clinical, or animal model systems are studied by biochemical, molecular, genetic or quantitative ultrastructural approaches. Submission of papers reporting genomic and proteomic approaches to identify and characterize parameters of biological control in a cellular context are encouraged. The areas covered include, but are not restricted to, conditions, agents, regulatory processes, or differentiation states that influence structure, cell cycle & growth control, structure-function relationships, or assembly mechanisms in cells, viruses, or supramolecular constructs, and signaling mechanisms mediating transcription. This scope extends to cell structure and function; organelle assembly; regulation of cell organization, reproduction or differentiation; the architectural organization and compartmentalization of nucleic acids and regulatory proteins within the nucleus and cytoplasm; the dynamics of intranuclear trafficking, placement and assembly of regulatory machinery for gene expression; and to the development, organization or remodeling of tissues. Manuscripts are to be submitted to an Executive Editor or Field Editor .

Executive Editors:

C. Fred Fox
Department of Microbiology and Molecular Genetics
University of California
609 CE Young Dr East, 1602 MSB
Los Angeles, CA 90095-1489
Telephone: (310) 825-9329
Fax: (310) 206-1703
E-mail: fredfox@microbio.ucla.edu

Gary S. Stein
Department of Biochemistry
The University of Vermont
Burlington, VT 05405
Telephone: (802) 656-6613
E-mail: gary.stein@uvm.edu
Managing Editor: Nicholas Yves Thompson
E-mail: Nicholas.Thompson@med.uvm.edu

Max M. Burger
Novartis Science Board
Novartis International AG
WKL 125.13.02
CH-4002 Basel, Switzerland
Telephone: (41) 61 696-7690
TeleFax: (41) 61 696-7693
E-mail: max.burger@novartis.com
Editorial Assistant: Connie Albrecht
E-mail: cornelia.albrecht@novartis.com

ONLINE MANUSCRIPT SUBMISSION

crosscheck

The journal to which you are submitting your manuscript employs a plagiarism detection system. By submitting your manuscript to this journal you accept that your manuscript may be screened for plagiarism against previously published works.



COPE

The Journal of Cellular Biochemistry is a member of, and subscribes to the principles of, the Committee on Publication Ethics (COPE) (www.publicationethics.org).

New Journal Submission Limitations

Journal of Cellular Biochemistry has recently adopted manuscript limitations for figures and references that are applicable to all newly submitted manuscripts. Strict adherence to these limitations during manuscript creation will allow for an expeditious peer-review process. The Journal thanks you in advance for your cooperation.

References: Should be limited to 50. (A maximum of 25 table and figure footnotes is allowed, if necessary.)

Figures: No more than 8 figures may be presented, approximately equivalent to 3 pages-worth total. Figures should be sized to one column width (20 picas), or two column width (40 picas), as appropriate. Image height may not exceed 40 picas. Multi-panel images should be composed as a single image with width and height limitations applying to the final, combined image. Image resolution must be at least 300 dpi for raster images (e.g., photographs, gels, stains) and 600 dpi for line-art images (e.g., charts and graphs). Image-related text and labeling must be clearly legible, a font size of 10 points or greater should be present in the final image


Journal of Cellular Biochemistry has a completely digital submission, review, and production process. We therefore ask for production-quality files at submission of your article. Following the guidelines below will expedite the processing, review, and publication of your article should it be accepted. Manuscripts submitted in incorrect formats will be returned for resubmission.

TEXT
Submit your text in DOC, DOCX, or RTF format.

Do not embed figures or tables in this document; these should be submitted as separate files.

TABLES
Tables should be created with a word processor and saved in either DOC, DOCX, or RTF format. Do not embed tables in your text.

FIGURES
No more than 8 figures may be presented, approximately equivalent to 3 pages-worth total. Figures should be sized to one column width (20 picas), or two column width (40 picas), as appropriate. Image height may not exceed 40 picas. Multi-panel images should be composed as a single image with width and height limitations applying to the final, combined image. Image resolution must be at least 300 dpi for raster images (e.g., photographs, gels, stains) and 600 dpi for line-art images (e.g., charts and graphs). Image-related text and labeling must be clearly legible, a font size of 10 points or greater should be present in the final image.

To ensure the highest print quality, your figures must be submitted in TIF or EPS format according to the following minimum resolutions:

1200 dpi (dots per inch) for black and white line art (simple bar graphs, charts, etc.)
300 dpi for halftones (black and white photographs)
600 dpi for combination halftones (photographs that also contain line art such as labeling or thin lines)

Vector-based figures (e.g. figures created in Adobe Illustrator) should be submitted in EPS format.

COLOR FIGURES

In addition to the above resolution guidelines, color figures must be submitted in a CMYK colorspace. Do not submit color figures as RGB.

UNACCEPTABLE FIGURE FORMATS

Do not submit figures in any of the following formats: JPG,GIF,PSD,CRD, PCT, PPT, PDF, XLS, DOC, DOCX, BMP, 123 (or other Lotus formats).


TO SUBMIT YOUR MANUSCRIPT ONLINE:

- Please submit your manuscript online at http://mc.manuscriptcentral.com/jcb-wiley .

- Click on "Check for Existing Account" . If you do not already have an account, click on "Create an Account" . Be sure to enter Keywords .

- Follow instructions carefully. Please review that your submission has uploaded correctly before clicking on the "Submit" button .

- On completion of a successful submission, a confirmation screen with manuscript will appear and you will receive an e-mail confirming that the manuscript has been received by the Journal. If this does not happen, please check your submission and/or contact tech support at edsupport@wiley.com .

Wiley-Japan can provide authors in Japan with a list of recommended services to check and improve the English of their papers before submission. Please visit http://www.wiley.co.jp/journals/editcontribute.html for more information.

ARTICLE CATEGORIES:

Articles are full-length papers presenting complete descriptions of original research, which have not been published and are not being considered for publication elsewhere.

Fast Track articles are papers that present original timely research of exceptional significance and should make an important contribution to the field. Fast Track manuscripts must be concise: limited to 12 double spaced typed manuscript pages, a maximum of 35 references, and 4 items for the presentation of data (e.g., figures, tables, micrographs). Authors who wish to have their manuscript considered for publication in Fast Track should include a brief indication of reasons why the manuscript is suitable for "fast tracking" in their cover letter. The names, addresses (including e-mail), telephone, and fax numbers of five potential reviewers must also be provided. Fast Track manuscripts should be submitted to one of the Executive Editors.

Prospects are topical overviews on emerging areas of research. They summarize key problems, concepts, experimental approaches, and research opportunities that characterize a subject area. Prospects should not include previously unpublished research results. The Editors generally invite them; authors who wish to submit a Prospect should first consult with the Editors.

Viewpoints include news items, meeting summaries and announcements, book reviews and letters to the Editor. Submitted Viewpoints are rapidly reviewed and appear in the next printed issue of the Journal.

Benchmarks section of Journal of Cellular Biochemistry presents novel techniques and strategies. Each article concisely evaluates opportunities, strengths and limitations of experimental approaches that can expand insight into biology and pathology. Specific protocols are encouraged for inclusion as supplementary material. “Benchmark” articles will be available on PubMed.

The objective is to provide access to novel experimental strategies. “Benchmark” articles should be developed to enhance awareness of capabilities to resolve complexities of cell structure and function. Submission of articles that focus on development of technologies and instrumentation to enable exploration of regulatory mechanisms previously unapproachable are encouraged. Coverage of topics can include (but not limited) to:

-Cell-based and animal models for in vitro and in vivo validation of molecular components to regulatory networks that mediate cell cycle control, proliferation, phenotype, cell fate and responsiveness to physiological cues.

-Breakthroughs in imaging and experimental approaches to discriminate subtleties in common or total control contributing to resolve and complexities in biological processes that include development, lineage commitment, tissue remodeling, apoptosis, pluripotency transformation and tumorigenesis.

-Capabilities to acquire, configure and integrate data from a rapidly evolving high throughput genomic and proteomic screens.

-Bioinformatic strategies that support dimensions for biological control that link to the prevention, early detection and treatment of human disease.

Abstract: In 150 words describe capability of the method to provide novel insights into biological/biomedical control. Indicate applications for resolving fundamental regulatory mechanisms and/or clinically relevant questions. Present validations for the approach and summarize strengths as well as potential limitations.

Presentation: Begin each “Benchmark” with an introduction that provides the background for the method. Focus on the unique capabilities of the approach to address compelling biological/biomedical questions. Highlight opportunities to increase resolution and/or scope of structural as well as regulatory parameters that can be evaluated.

The method should then be presented with schematic illustrations and described with emphasis on instrumentation, resolution, experimental applications and complexities with alternative strategies. Validation should be presented and examples of data that can be anticipated are encouraged. Considerations of options to accommodate specialized requirements is informative.

“Benchmarks” should not exceed 2500–3500 words. To maximize the utility of “Benchmarks” it is important for descriptions of technology to be accessible to a broad audience.

Experimental protocols and specifications for instrumentation and reagents are valuable; but, in general, will be presented as supplemental material that is available online. “Benchmarks” articles will be invited by the Journal of Cellular Biochemistry editors to cover emerging methods and strategies. However, authors are encouraged to submit unsolicited manuscripts or letters of inquiry to the editorial office.

SECTIONS: Original Research Articles should be organized in the sequence: Abstract, Introduction (without heading), Materials & Methods, Results, Discussion, Acknowledgments, References, Tables, Legends, and Figures. Use subheadings and paragraph titles whenever possible. Define unusual abbreviations at first mention. Units of measure must be written in metric units.

TITLE PAGE must contain:
- Complete article title
- Names & affiliations (institutions) of all authors, with the corresponding author indicated by an asterisk.
- Institution(s) at which the work was performed with city & state. Affiliations must be listed at the departmental level. Each distinct affiliation should be listed as a separate entity, with a superscript number that links it to the individual author(s).
- Complete name, address, telephone number, fax number & e-mail address of corresponding author.
- A running head of not more than 45 characters, including spaces.
- Bullet point keywords (in bold).
- Total number of text figures & tables.
- All grant information should be provided in the following format: Contract grant sponsor:___; Contract grant number:___.

ABSTRACT: This should summarize the major findings and conclusions in the paper in not more than 250 words compressed into a single paragraph. The abstract should be intelligible without reference to the rest of the paper.

MATERIALS AND METHODS:
For all studies involving the use of animals, the following conditions should be met:
a. All research animals must have been obtained and used in compliance with federal, state, and local laws and institutional regulations.
b. The Journal recommends that animals be maintained in accordance with the guidelines of the NIH (Guide for the Care and Use of Laboratory Animals, 1996), the European Communities Council, or equivalent regulatory guidelines in other countries. Any veterinary accreditation should be noted in the manuscript.
c. The author must have received permission from their institutional Animal Care and Use Committee, and the manuscript must indicate that such approval was received."

LITERATURE CITED:
Should be limited to 50. (A maximum of 25 table and figure footnotes is allowed, if necessary.)

Reference should be made only to articles that are published or in press. Unpublished results and personal communications should be cited parenthetically in the text. Authors are responsible for the accuracy of the references. References in the text to the literature should be made by author's name followed by year of publication:
. . . studies by Briggs (1993) reveal . . .
. . . studies by Briggs and Porter (1994) reveal . . .
. . . an earlier report (Briggs, 1994) . . .
. . . earlier reports (Briggs, 1993; Briggs and Porter, 1993, 1994) . . .

If there are more than two authors, use the first author and et al. The final list must be alphabetized and include only references cited in the text. Each entry must include the names of all authors, complete title of the work cited, and inclusive page numbers. Abbreviations of journal titles should follow those used in Index Medicus.

Examples:
Journal Article:
Wright CD, Mülsh A, Busse R, Newman P. 1998. Generation of nitric oxide by human neutrophils. Biochem Biophys Res Commun 29:813-820.

Book Cited:
Whistler P, Wilks S. 1989. Methods in carbohydrate chemistry. New York:Academic Press. p.244

Book Chapter Cited:
Smith A. 1990. Transport of antigens: mechanisms and biological and regulatory consequences. In: Ariano MA, editor. Biosynthesis of heme and chlorophylls. New York:Wiley-Liss. p 230-278.

LEGENDS: Each illustration must have a legend and be numbered consecutively with arabic numerals. Abbreviations pertaining to the labeling of figures should be listed once, alphabetically, and placed before the first figure containing these abbreviations.

TABLES: Each table must be submitted as a separate file.

ILLUSTRATIONS: Use illustrations sparingly; they should not duplicate information already made clear in the text. All color figures will be reproduced in full color in the online edition of the journal at no cost to authors. Authors are requested to pay the cost of reproducing color figures in print ($500 per page of color). Authors are encouraged to submit color illustrations that highlight the text and convey essential scientific information. For best reproduction, bright, clear colors should be used. Dark colors against a dark background do not reproduce well; please place your color images on a white background wherever possible. Please contact JCB Production at JCBprod@wiley.com for further information. All graphics and lettering must be legible after reduction in size. Illustrations must be numbered in order of appearance with roman numerals and keyed into the text.


COPYRIGHT/LICENSING
If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.
For authors signing the copyright transfer agreement:
If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:
CTA Terms and Conditions http://authorservices.wiley.com/bauthor/faqs_copyright.asp
For authors choosing OnlineOpen:
If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):
Creative Commons Attribution License OAA
Creative Commons Attribution Non-Commercial License OAA
Creative Commons Attribution Non-Commercial -NoDerivs License OAA
To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services http://authorservices.wiley.com/bauthor/faqs_copyright.asp and visit http://www.wileyopenaccess.com/details/content/12f25db4c87/Copyright--License.html
If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit: http://www.wiley.com/go/funderstatement.


Conflict of Interest Disclosure
Wiley-Blackwell requires that all authors disclose any potential sources of conflict of interest. Any interest or relationship, financial or otherwise, that might be perceived as influencing an author’s objectivity is considered a potential source of conflict of interest. These must be disclosed when directly relevant or indirectly related to the work that the authors describe in their manuscript. Potential sources of conflict of interest include but are not limited to patent or stock ownership, membership of a company board of directors, membership of an advisory board or committee for a company, and consultancy for or receipt of speaker’s fees from a company. The existence of a conflict of interest does not preclude publication in this journal.

If the authors have no conflict of interest to declare, they must also state this at submission.It is the responsibility of the corresponding author to review this policy with all authors and to collectively list in the cover letter to the Editor-in-Chief, in the manuscript (under the Acknowledgments section), and in the online submission system ALL pertinent commercial and other relationships.

Supplementary Online Material: Authors may submit supplementary material for their articles to be posted in the electronic version of the journal. There are no restrictions on file types, however please keep in mind that the more universal the file type the more accessible it will be to the community. All supplementary material must be submitted online as "Supplementary Material" for peer review.

Reprints: Reprints may be purchased at https://caesar.sheridan.com/reprints/redir.php?pub=10089&acro=jcb.

Note to NIH Grantees. Pursuant to NIH mandate, Wiley-Blackwell will post the accepted version of contributions authored by NIH grant-holders to PubMed Central upon acceptance. This accepted version will be made publicly available 12 months after publication. For further information, see www.wiley.com/go/nihmandate .


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