Journal of Cellular Physiology

Cover image for Vol. 229 Issue 7

Edited By: Gary S. Stein, Harvey M. Florman and Constance E. Brinckerhoff

Impact Factor: 4.218

ISI Journal Citation Reports © Ranking: 2012: 13/80 (Physiology); 63/185 (Cell Biology)

Online ISSN: 1097-4652

Virtual Issues

Stem Cell Biology

Published: February 2014

Advances in stem cell biology are providing a platform for mechanistic insight into biological control in areas that have been historically confined to insightful, but descriptive observations. Equally important, lessons learned from understanding the rules that govern pluripotency and lineage commitment are paving the way for breakthroughs in regenerative medicine and cell-based therapies. We have assembled a series of research articles and reviews on stem cell biology that were recently published in the Journal of Cellular Physiology. These articles encapsulate fundamental dimensions of control in stem cells that are beginning to be understood from the perspectives of genetic and epigenetic control as well as within the context of regulatable plasticity.

Culture under low physiological oxygen conditions improves the stemness and quality of induced pluripotent stem cells
Guo, C.-W., Kawakatsu, M., Idemitsu, M., Urata, Y., Goto, S., Ono, Y., Hamano, K. and Li, T.-S.

Carcinoma-associated fibroblasts: Non-neoplastic tumour-promoting mesenchymal cells
Polanska, U. M. and Orimo, A.

Genetic and molecular characterization of the human Osteosarcoma 3AB-OS cancer stem cell line: A possible model for studying osteosarcoma origin and stemness
Di Fiore, R., Fanale, D., Drago-Ferrante, R., Chiaradonna, F., Giuliano, M., De Blasio, A., Amodeo, V., Corsini, L. R., Bazan, V., Tesoriere, G., Vento, R. and Russo, A.

Regeneration of articular cartilage by adipose tissue derived mesenchymal stem cells: Perspectives from stem cell biology and molecular medicine
Wu, L., Cai, X., Zhang, S., Karperien, M. and Lin, Y.

An activator of the cAMP/PKA/CREB pathway promotes osteogenesis from human mesenchymal stem cells
Kim, J.-M., Choi, J. S., Kim, Y.-H., Jin, S. H., Lim, S., Jang, H.-J., Kim, K.-T., Ryu, S. H. and Suh, P.-G.

Nanog regulates molecules involved in stemness and cell cycle-signaling pathway for maintenance of pluripotency of P19 embryonal carcinoma stem cells
Choi, S.-C., Choi, J.-H., Park, C.-Y., Ahn, C.-M., Hong, S.-J. and Lim, D.-S.

The abbreviated pluripotent cell cycle
Kapinas, K., Grandy, R., Ghule, P., Medina, R., Becker, K., Pardee, A., Zaidi, S. K., Lian, J., Stein, J., van Wijnen, A. and Stein, G.

Editor's Choice

Published: May 2013

Journal of Cellular Physiology is pleased to announce their Virtual Issue on recent hot topics.

Evidence for pivotal roles of genetic and epigenetic control of gene expression is rapidly accruing. The importance of genetic and epigenetic mechanisms is expanding understanding of biological processes. Applications for therapeutically targeting cancer cells are emerging. These strategies are featured in six recent papers that were recently published in Journal of Cellular Physiology. Aberrant regulation in transformed and tumor cells is presented and the power of experimental strategies including systems of biology and genomic approaches are presented to illustrate the necessity for defining regulatory networks that integrate parameters of control which are operative in biology and compromised in pathology.

Systems biology provides new insights into the molecular mechanisms that control the fate of embryonic stem cells hematopoietic stem cell fate
Sunil K. Mallanna and Angie Rizzino

Phosphorylation of histone H1 by P-TEFb is a necessary step in skeletal muscle differentiation
Siobhan K. O'Brien, Kendall L. Knight and Tariq M. Rana

Integrating post-transcriptional regulation into the embryonic stem cell gene regulatory network
Paul A. Cassar and William L. Stanford

Metaboloepigenetics: Interrelationships between energy metabolism and epigenetic control of gene expression
Dallas R. Donohoe and Scott J.Bultman

The abbreviated pluripotent cell cycle
Kristina Kapinas, Rodrigo Grandy, Prachi Ghule, Ricardo Medina, Klaus Becker, Arthur Pardee, Sayyed K. Zaidi, Jane Lian, Janet Stein, Andre van Wijnen and Gary Stein

FOXP3 expression in tumor cells and implications for cancer progression
Tiziana Triulzi, Elda Tagliabue, Andrea Balsari and Patrizia Casalini